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teer decrease » greater decrease (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), use decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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11721
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11722
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11723
DataSheet1_Monoclonal Antibodies Targeting IL-5 or IL-5Rα in Eosinophilic Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis.DOCX
Published 2021“…This meta-analysis aimed to determine the efficacy and safety of anti-IL-5 therapy in eosinophilic COPD.</p><p>Methods: We searched the PubMed, Web of Science, Embase, and Cochrane Library databases from inception to August 2020 (updated in June 2021) to identify studies comparing anti-IL-5 therapy (including mepolizumab, benralizumab, and reslizumab) with placebo in eosinophilic COPD patients.…”
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11724
DataSheet1_Preparation of rambutan-like Co0.5Ni0.5Fe2O4 as anode for high–performance lithium–ion batteries.PDF
Published 2022“…<p>NiFe<sub>2</sub>O<sub>4</sub> is a kind of promising lithium ion battery (LIB) electrode material, but its commercial applications have been limited due to the electronic insulation property and large volume expansion during the conversion reaction process, which results in rapid capacity decrease and poor cycling stability. We synthesized rambutan-like Co<sub>0.5</sub>Ni<sub>0.5</sub>Fe<sub>2</sub>O<sub>4</sub> using the self-templating solvothermal method. …”
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11725
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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11726
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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11727
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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11728
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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11729
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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11730
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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11731
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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11732
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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11733
Supplemental figures for manuscript entitled: Tumor Suppressors RBL1 and PTEN are Epigenetically Silenced in IPF Mesenchymal Progenitor Cells by a CD44/Brg1/PRMT5 Regulatory Comple...
Published 2024“…We demonstrate that expression of the tumor suppressor genes <i>rbl1</i> and <i>pten</i> is decreased in IPF MPCs. …”
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11734
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11735
LP I<sub>h</sub> metamodulation is rapid and reversible.
Published 2015“…The percent change in LP I<sub>h</sub> G<sub>max</sub> relative to t = 0 is plotted (mean±SEM, increases are positive, decreases are negative). …”
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11736
Cdk1-dependent phosphorylation of KIF4A at S1186 regulates the chromosomal localization of KIF4A during mitosis.
Published 2018“…Arrowheads indicate chromosome bridge formation. Bar, 5 μm. EGFP-KIF4A WT localized to the chromosome, whereas the localization of EGFP-KIF4A S1186A to the chromosomes was severely decreased after NEB. …”
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11737
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11738
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11739
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11740
Discovery of Novel 3‑Phenylpiperidine Derivatives Targeting the β‑Catenin/B-Cell Lymphoma 9 Interaction as a Single Agent and in Combination with the Anti-PD‑1 Antibody for the Tre...
Published 2023“…Among them, compound <b>41</b> showed the best IC<sub>50</sub> (0.72 μM) in a competitive fluorescence polarization assay and a <i>K</i><sub>D</sub> value of 0.26 μM for the β-catenin protein. …”