Table_2_Cerebral Small Vessel Disease Load Predicts Functional Outcome and Stroke Recurrence After Intracerebral Hemorrhage: A Median Follow-Up of 5 Years.DOCX by Mangmang Xu (10165901)

“…Death occurred in 36.1% (13/36) of patients with CMBs ≥ 10 compared with 18.8% (22/117) in those with CMB < 10 (adjusted HR 2.669, 95% CI 1.248–5.707, p = 0.011). In addition, the cumulative CSVD score ≥ 2 was associated with a decreased survival rate (adjusted HR 3.140, 95% CI 1.066–9.250, p = 0.038).…”

Presentation_1_A Novel Multifunctional 5,6-Dimethoxy-Indanone-Chalcone-Carbamate Hybrids Alleviates Cognitive Decline in Alzheimer’s Disease by Dual Inhibition of Acetylcholinester... by Chan Liu (5545364)

“…</p>Results<p>We found that AP5 can simultaneously bind to the peripheral and catalytic sites of AChE by molecular docking. …”

Table_1_Cerebral Small Vessel Disease Load Predicts Functional Outcome and Stroke Recurrence After Intracerebral Hemorrhage: A Median Follow-Up of 5 Years.DOCX by Mangmang Xu (10165901)

“…Death occurred in 36.1% (13/36) of patients with CMBs ≥ 10 compared with 18.8% (22/117) in those with CMB < 10 (adjusted HR 2.669, 95% CI 1.248–5.707, p = 0.011). In addition, the cumulative CSVD score ≥ 2 was associated with a decreased survival rate (adjusted HR 3.140, 95% CI 1.066–9.250, p = 0.038).…”

Presentation_1_A Novel Multifunctional 5,6-Dimethoxy-Indanone-Chalcone-Carbamate Hybrids Alleviates Cognitive Decline in Alzheimer’s Disease by Dual Inhibition of Acetylcholinester... by Chan Liu (5545364)

“…</p>Results<p>We found that AP5 can simultaneously bind to the peripheral and catalytic sites of AChE by molecular docking. …”

Table 5_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.xls by Yuanxi Mo (22090130)

Table_3_Cerebral Small Vessel Disease Load Predicts Functional Outcome and Stroke Recurrence After Intracerebral Hemorrhage: A Median Follow-Up of 5 Years.docx by Mangmang Xu (10165901)

“…Death occurred in 36.1% (13/36) of patients with CMBs ≥ 10 compared with 18.8% (22/117) in those with CMB < 10 (adjusted HR 2.669, 95% CI 1.248–5.707, p = 0.011). In addition, the cumulative CSVD score ≥ 2 was associated with a decreased survival rate (adjusted HR 3.140, 95% CI 1.066–9.250, p = 0.038).…”

Table_4_Cerebral Small Vessel Disease Load Predicts Functional Outcome and Stroke Recurrence After Intracerebral Hemorrhage: A Median Follow-Up of 5 Years.DOCX by Mangmang Xu (10165901)

“…Death occurred in 36.1% (13/36) of patients with CMBs ≥ 10 compared with 18.8% (22/117) in those with CMB < 10 (adjusted HR 2.669, 95% CI 1.248–5.707, p = 0.011). In addition, the cumulative CSVD score ≥ 2 was associated with a decreased survival rate (adjusted HR 3.140, 95% CI 1.066–9.250, p = 0.038).…”

The <i>in silico</i> effect prothrombin complex concentrates with or without co-supplementation of antithrombin in cirrhosis. by Romy M. W. Kremers (819412)

DataSheet1_Effects of Maren Pills on the Intestinal Microflora and Short-Chain Fatty Acid Profile in Drug-Induced Slow Transit Constipation Model Rats.docx by Yu Zhan (462171)

“…The 16S rDNA sequencing results showed that MRW improved the colonic microflora structure in colonic contents of STC rats, mainly by increasing Lactobacillus and decreasing Prevotella. Finally, we found that MRW regulated the SCFA metabolism in the colonic contents of the STC rats, mainly by increasing the contents of acetic acid, propionic acid, and butyric acid; the relative abundance of Lactobacillus was positively correlated with either contents of acetic acid, propionic acid, and butyric acid, and the relative abundance of Clostridium was negatively correlated.…”

Table1_Effects of Maren Pills on the Intestinal Microflora and Short-Chain Fatty Acid Profile in Drug-Induced Slow Transit Constipation Model Rats.docx by Yu Zhan (462171)

“…The 16S rDNA sequencing results showed that MRW improved the colonic microflora structure in colonic contents of STC rats, mainly by increasing Lactobacillus and decreasing Prevotella. Finally, we found that MRW regulated the SCFA metabolism in the colonic contents of the STC rats, mainly by increasing the contents of acetic acid, propionic acid, and butyric acid; the relative abundance of Lactobacillus was positively correlated with either contents of acetic acid, propionic acid, and butyric acid, and the relative abundance of Clostridium was negatively correlated.…”

DataSheet_1_SARS-CoV-2 modulates inflammatory responses of alveolar epithelial type II cells via PI3K/AKT pathway.pdf by Ahmed A. Al-Qahtani (10304843)

“…The results showed that SARS-CoV-2 S protein decreased the expression and secretion of IL8, IL6 and TNFα, 6 hours following stimulation, while it had no effect on IFNα, CXCL5 and PAI-1 expression. …”

Presentation 1_Changes to inflammatory markers during 5 years of viral suppression and during viral blips in people with HIV initiating different integrase inhibitor based regimens... by Nicholas T. Funderburg (9422033)

“…Additionally, it remains unknown whether transient increases in viral load (“blips”) during ART are associated with increases in inflammation.</p>Methods<p>We utilized cryopreserved samples from treatment-naïve PWH enrolled in two Phase 3 clinical trials investigating the efficacy and safety of bictegravir, emtricitabine and tenofovir alafenamide (B/F/TAF) or dolutegravir, abacavir, and lamivudine (DTG/ABC/3TC) or DTG + F/TAF over a 5-year window (GS-US-380-1489/1490). …”

Flowchart for the SI model of <i>T</i>. <i>cruzi</i> transmission in a community of competent and non-competent hosts. by Alheli Flores-Ferrer (2151817)

Table_5_Verification of Resveratrol Inhibits Intestinal Aging by Downregulating ATF4/Chop/Bcl-2/Bax Signaling Pathway: Based on Network Pharmacology and Animal Experiment.xls by Tian-hao Liu (9109460)

Effect of fenretinide and its metabolites on SCD expression and activity. by Eugenia Poliakov (116500)

“…<p>A) SCD1 protein expression is decreased after treatment with fenretinide, and its metabolite 3-keto-HPR. …”

LFP changes in the CA1 area during learning sessions using 1:1 ratio schedule. by M. Teresa Jurado-Parras (2155477)

“…<p>(<i>A-F</i>) Mean peak values (circles) and best fits (lines) of the spectral power corresponding to LPFs recorded during each learning session in WT (open circles and continuous lines) and GABA_B1a^-/- (closed circles and dotted lines) mice for all spectral bands in <i>A</i> (1–100 Hz), and for selected spectral bands in <i>B-F</i> (1–3 Hz in <i>B</i>, 3–8 Hz in <i>C</i>, 8–12 Hz in <i>D</i>, 12–30 Hz in <i>E</i> and 30–100 Hz in <i>F</i>). …”

Silencing KDM2A enhances angiogenic tubulogenesis. by Wasia Rizwani (369727)

“…<p>(A) HUVEC cells were transfected with either control siRNA or KDM2A siRNA (75 pmol). 24 hr later, cells were plated on matrigel in complete media (asynchronous) or with or without 100 ng/ml VEGF. …”

Deletion of <i>Ulk1</i> inhibits neointima formation by enhancing KAT2A/GCN5-mediated acetylation of TUBA/α-tubulin <i>in vivo</i> by Changhan Ouyang (3637546)

“…However, the role of ULK1 in neointima formation remains unclear. We aimed to determine how <i>Ulk1</i> deletion affected neointima formation and to investigate the underlying mechanisms. …”

Image_5_Transcriptome and miRNome Analysis Provide New Insight Into Host Lipid Accumulation, Innate Immunity, and Viral Persistence in Hepatitis C Virus Infection in vitro.TIF by Chong Li (120471)

Table_5_Transcriptome and miRNome Analysis Provide New Insight Into Host Lipid Accumulation, Innate Immunity, and Viral Persistence in Hepatitis C Virus Infection in vitro.XLS by Chong Li (120471)