Image_5_In Vitro Exposure of Primary Human T Cells and Monocytes to Polyclonal Stimuli Reveals a Basal Susceptibility to Display an Impaired Cellular Immune Response and Develop Se... by Rebeca Viurcos-Sanabria (12994449)

“…Then, we started a six-month follow-up and registered 12 participants who got SARS-CoV-2 infection, from whom we retrospectively analyzed the basal immune response pattern of T cells and monocytes. …”

Effect of indole in combination with cecal SCFAs on <i>hilA</i> expression. by Nandita Kohli (2049115)

“…Data shown are the mean fold decrease (n = 3) in expression of <i>hilA</i> with treatment relative to the control: <i>hilA</i> expression in presence of 200 mM NaCl. * denotes statistical significance relative to cecal SCFAs alone at <i>p</i> < 0.05 using the Student’s <i>t</i>-test. …”

N’-Ferrocenylmethyl-N’-phenylbenzohydrazide as a potential DNA binding compound: a combined experimental and computational study by Mouada Hanane (17308566)

“…Furthermore, molecular dynamics of the docked complex of FhD with DNA were carried out for 100 ns followed by MM-GBSA to have a deep understanding of the complex’s dynamic behavior in physiological systems, and to determine the Gibbs free energy which was −14.31 Kcal/mol over a 100 ns window. …”

Minidysferlin do not improve muscle histology. A by William Lostal (162211)

“…It should be noted that this fold correspond to a mean expression and that each individual fiber can express more or less than this means. …”

Supplemental figures for manuscript entitled: Tumor Suppressors RBL1 and PTEN are Epigenetically Silenced in IPF Mesenchymal Progenitor Cells by a CD44/Brg1/PRMT5 Regulatory Comple... by Craig Henke (9406202)

“…We demonstrate that expression of the tumor suppressor genes <i>rbl1</i> and <i>pten</i> is decreased in IPF MPCs. …”

Data_Sheet_1_SHIP-1 Regulates Phagocytosis and M2 Polarization Through the PI3K/Akt–STAT5–Trib1 Circuit in Pseudomonas aeruginosa Infection.pdf by Shugang Qin (8591460)

“…We found that infected-SHIP-1^−/− mice exhibited decreased survival rates, increased inflammatory responses, and susceptibility owing to elevated expression of PI3K than wild-type (WT) mice. …”

Image_5_Induction of Protective Immunity by a Single Low Dose of a Master Cell Bank cGMP-rBCG-P Vaccine Against the Human Metapneumovirus in Mice.tiff by Jorge A. Soto (6059606)

Table_1_The role of miR-10a-5p in LPS-induced inhibition of progesterone synthesis in goose granulosa cells by down-regulating CYP11A1.XLSX by Xinyi Guo (3755509)

“…We also determined that the downregulation of miR-10a-5p led to CYP11A1 expression. …”

Image_1_Characterization of Tg(Etv4-GFP) and Etv5RFP Reporter Lines in the Context of Fibroblast Growth Factor 10 Signaling During Mouse Embryonic Lung Development.JPEG by Matthew R. Jones (115795)

“…We found that both Tg(Etv4-GFP) and Etv5^{CreERT2−RFP} were primarily expressed in the epithelium of the lung during embryonic development. …”

Video_1_Characterization of Tg(Etv4-GFP) and Etv5RFP Reporter Lines in the Context of Fibroblast Growth Factor 10 Signaling During Mouse Embryonic Lung Development.MOV by Matthew R. Jones (115795)

“…We found that both Tg(Etv4-GFP) and Etv5^{CreERT2−RFP} were primarily expressed in the epithelium of the lung during embryonic development. …”

Video_2_Characterization of Tg(Etv4-GFP) and Etv5RFP Reporter Lines in the Context of Fibroblast Growth Factor 10 Signaling During Mouse Embryonic Lung Development.MOV by Matthew R. Jones (115795)

“…We found that both Tg(Etv4-GFP) and Etv5^{CreERT2−RFP} were primarily expressed in the epithelium of the lung during embryonic development. …”

CgHog1 negatively regulates CgSub2-CgHtz1 interaction. by Mahima Sagar Sahu (18555062)

“…<i>Cg</i> adherence analysis to A-498 cells.</b> Data represent mean ± SEM (n = 3). …”

DataSheet_1_Extracellular vesicle-associated microRNA-30b-5p activates macrophages through the SIRT1/ NF-κB pathway in cell senescence.pdf by Yu Xiao (150812)

“…Significantly more EVs were found in the supernatant of SEN than of control (CON) cell cultures, and SEN EVs were enriched in miR-30b-5p, which directly target sirtuin1 (SIRT1). In vitro, we found that SEN EV treatment resulted in increased cellular levels of interleukin-1β (IL-1β) and IL-6 and decreased levels of SIRT1. …”

Data Sheet 1_Isobavachalcone ameliorates Alzheimer disease pathology by autophagy-mediated clearance of amyloid beta and inhibition of NLRP3 inflammasome in primary astrocytes and... by Dilpreet Kour (10872766)

“…Subsequent brain tissue analysis revealed that IBC upregulated autophagic proteins to reduce the brain’s amyloid beta levels, resulting in decreased expression of neuroinflammation markers.</p>Conclusion<p>IBC effectively ameliorates AD pathology through autophagy-mediated clearance of Aβ and suppressing neuroinflammation in 5x-FAD mice.…”

Image5_MAP3K1 Variant Causes Hyperactivation of Wnt4/β-Catenin/FOXL2 Signaling Contributing to 46,XY Disorders/Differences of Sex Development.TIF by Hong Chen (108084)

Role of DNA methylation in expression control of the <i>IKZF3-GSDMA</i> region in human epithelial cells by Sanny Moussette (3797734)

“…To further characterize the effect of DNA methylation, we examined the impact of treatment with DNA methyltransferase inhibitor 5-aza-2’-deoxycytidine (5-aza-dC) that causes DNA demethylation, on expression and promoter methylation of the five 17q12-q21 genes in the human airway epithelium cell line NuLi-1, embryonic kidney epithelium cell line 293T and human adenocarcinoma cell line MCF-7. 5-aza-dC treatment led to upregulation of expression of <i>GSDMA</i> in all three cell lines. …”

DataSheet1_The Establishment of Quantitatively Regulating Expression Cassette with sgRNA Targeting BIRC5 to Elucidate the Synergistic Pathway of Survivin with P-Glycoprotein in Can... by Changping Deng (11894321)

“…<p>Quantitative analysis and regulating gene expression in cancer cells is an innovative method to study key genes in tumors, which conduces to analyze the biological function of the specific gene. In this study, we found the expression levels of Survivin protein (BIRC5) and P-glycoprotein (MDR1) in MCF-7/doxorubicin (DOX) cells (drug-resistant cells) were significantly higher than MCF-7 cells (wild-type cells). …”

Table_5_Rheumatoid Arthritis Patients, Both Newly Diagnosed and Methotrexate Treated, Show More DNA Methylation Differences in CD4+ Memory Than in CD4+ Naïve T Cells.xlsx by Kari Guderud (8448846)

<i>Empty Pericarp21</i> encodes a novel PPR-DYW protein that is required for mitochondrial RNA editing at multiple sites, complexes I and V biogenesis, and seed development in maiz... by Yong Wang (12837)

“…In consequence, the mutant became deficient with respect to the assembly and activity of mitochondrial complexes I and V. As six of the decreased editing sites in <i>emp21</i> overlap with the affected editing sites in <i>emp5-1</i>, and the editing efficiency at <i>rpl16</i>-458 showed a substantial reduction in the <i>emp21-1 emp5-4</i> double mutant compared with the <i>emp21-1</i> and <i>emp5-4</i> single mutants, we explored their interaction. …”

Table_2_Consequences of Social Distancing Measures During the COVID-19 Pandemic First Wave on the Epidemiology of Children Admitted to Pediatric Emergency Departments and Pediatric... by Michael Levy (49754)

“…A significant decline was reported in acute respiratory illness and LRTI in five studies with a median decrease of 63%. We did not find a consistent trend in the incidence of poisoning, but there was an increasing trend in burns, DKA, and a downward trend in trauma and unplanned surgeries.…”