Quinacrine modifies the <i>F. tularensis</i> MglA and SspA interaction in a bacterial two-hybrid system. by Algevis P. Wrench (276279)

“…<p>Transcription activation by the interaction between MglA and SspA from <i>F. tularensis</i> SCHU S4 decreases in the presence of quinacrine. …”

In Vitro Influence of Mycophenolic Acid on Selected Parameters of Stimulated Peripheral Canine Lymphocytes by Maciej Guzera (2636809)

“…The influence of MPA on apoptosis was dependent on the mechanism of cell activation and MPA concentration. MPA caused a decrease in the expression of lymphocyte surface antigens, CD3, CD8 and CD25. …”

Programmed Release METTL3-14 Inhibitor Microneedle Protects Myocardial Function by Reducing Drp1 m6A Modification-Mediated Mitochondrial Fission by Boyue Huang (17051857)

“…By employing hypoxia-ischemic and TGF-β1-induced fibrosis cell models, we found that METTL3-14 inhibition effectively decreased cardiomyocyte death through the reduction of mitochondrial fragmentation and inhibiting myofibrillar transformation. …”

The effects of activation of LHb–projecting vLGN/IGL neurons on NREM sleep. by Lu Huang (211625)

Autophagic homeostasis is required for the pluripotency of cancer stem cells by Tanveer Sharif (329961)

“…In this report, using both human and murine models of CSCs, we demonstrate that basal levels of autophagy are required to maintain the pluripotency of CSCs, and that this process is differentially regulated by the rate-limiting enzyme in the NAD⁺ synthesis pathway NAMPT (nicotinamide phosphoribosyltransferase) and the transcription factor POU5F1/OCT4 (POU class 5 homeobox 1). …”

Data_Sheet_1_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.DOCX by Ai Qing Yu (9774356)

“…Specifically, among the identified proteins, we found SIRT7 decrotonylated PHF5A, an alternative splicing (AS) factor, at K25. …”

Data_Sheet_2_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.XLS by Ai Qing Yu (9774356)

“…Specifically, among the identified proteins, we found SIRT7 decrotonylated PHF5A, an alternative splicing (AS) factor, at K25. …”

Data_Sheet_3_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.XLSX by Ai Qing Yu (9774356)

“…Specifically, among the identified proteins, we found SIRT7 decrotonylated PHF5A, an alternative splicing (AS) factor, at K25. …”

Birds invest wingbeats to keep a steady head and reap the ultimate benefits of flying together by Lucy A. Taylor (492318)

“…Despite this, no studies have quantified the biomechanical consequences of flying in a cluster flock or pair relative to flying solo. Here, we compared the flight characteristics of homing pigeons (<i>Columba livia</i>) flying solo and in pairs released from a site 7 km from home, using high-precision 5 Hz global positioning system (GPS) and 200 Hz tri-axial accelerometer bio-loggers. …”

Targeted genetic screening in mice through haploid embryonic stem cells identifies critical genes in bone development by Meizhu Bai (6905372)

“…Whereas <i>Rln1</i>^{<i>−/−</i>} mice exhibited small skeletal size only at birth, <i>Irx5</i>^{<i>−/−</i>} mice showed skeletal abnormalities both in postnatal and adult phases due to decreased bone mass and increased bone marrow adipogenesis. …”

The implementation process for the LCG. by Anna Ramö Isgren (16819339)

“…</p><p> Trial registration </p><p>The trial has been registered at <a href="https://www.clinicaltrials.gov" target="_blank">www.clinicaltrials.gov</a>: <a href="https://clinicaltrials.gov/ct2/show/NCT05560802" target="_blank">NCT05560802</a>.…”

Primary and secondary/exploratory outcomes. by Anna Ramö Isgren (16819339)

“…</p><p> Trial registration </p><p>The trial has been registered at <a href="https://www.clinicaltrials.gov" target="_blank">www.clinicaltrials.gov</a>: <a href="https://clinicaltrials.gov/ct2/show/NCT05560802" target="_blank">NCT05560802</a>.…”

Binuclear Manganese Compounds of Potential Biological Significance. 1. Syntheses and Structural, Magnetic, and Electrochemical Properties of Dimanganese(II) and -(II,III) Complexes... by Lionel Dubois (1503907)

“…<b>1</b>(CH₃OH) crystallizes in the monoclinic system, space group <i>P</i>2₁/<i>c</i>, with <i>a</i> = 10.9215(6) Å, <i>b</i> = 20.2318(12) Å, <i>c</i> = 19.1354(12) Å, α = 90°, β = 97.5310(10)°, γ = 90°, <i>V</i> = 4191.7 ų, and <i>Z</i> = 4. …”

Poly(l‑lactic acid) Microdomain as a Nanopolarization Rotator in a Flexible, Elastic, and Transparent Polyurethane by Kai Wang (21246)

“…Small-angle X-ray scattering/wide-angle X-ray scattering results exclude any periodic structural evolution in a length scale of 0.1–100 nm, and we conclude that the chiral PLLA segment induced such a polarization rotation phenomenon. …”

DRLE alleviated ISO-induced heart injury. by Lung-Shuo Wang (3391244)

Melittin and alamethicin induce calcein leakage. by Rianne Bartelds (1343631)

Image_1_Deletion of Kcnj16 in Mice Does Not Alter Auditory Function.TIF by Jun Lv (337346)

“…In this study, we found that Kir5.1 was expressed in the mouse cochlea. …”

Image_2_Deletion of Kcnj16 in Mice Does Not Alter Auditory Function.TIF by Jun Lv (337346)

“…In this study, we found that Kir5.1 was expressed in the mouse cochlea. …”

Image_3_Deletion of Kcnj16 in Mice Does Not Alter Auditory Function.TIF by Jun Lv (337346)

“…In this study, we found that Kir5.1 was expressed in the mouse cochlea. …”

Image_4_Deletion of Kcnj16 in Mice Does Not Alter Auditory Function.TIF by Jun Lv (337346)

“…In this study, we found that Kir5.1 was expressed in the mouse cochlea. …”