Flexible Reaction Pocket on Bulky Diphosphine–Ir Complex Controls Regioselectivity in <i>para</i>-Selective C–H Borylation of Arenes by Brandon E. Haines (1312221)

“…It is shown that an increase in the steric bulk of the ligand by introducing bulkier 3,5-substituents to the phenyl rings of the diarylphosphino groups of <b>L1</b> <i>decreases</i> the <i>para</i>-selectivity. …”

m⁶A mRNA methylation controls autophagy and adipogenesis by targeting <i>Atg5</i> and <i>Atg7</i> by Xinxia Wang (301455)

“…Furthermore, we generated an adipose-selective <i>fto</i> knockout mouse and find that FTO deficiency decreased white fat mass and impairs ATG5- and ATG7-dependent autophagy <i>in vivo</i>. …”

All-Atom Simulations Reveal the Effect of Membrane Composition on the Signaling of the NKG2A/CD94/HLA‑E Immune Receptor Complex by Martin Ljubič (15680161)

“…These variations are particularly evident in the intracellular domain of NKG2A, manifested as changes in mobility, tyrosine exposure, and interdomain communication. Additionally, we found that a large concentration of negative charge at the surface of the POPA-based membrane greatly increased the number of contacts with lipid molecules and significantly decreased the exposure of intracellular NKG2A ITIM regions to water molecules, thus likely halting the signal transduction process. …”

Effect of ELX-02 on exogenous CTNS protein expressed from p<i>CMV</i>-driven constructs. by Emma J. Brasell (8081969)

Hematopoietic and neuronal SDS phenotypes are p53-dependent. by Marina E. Tourlakis (751986)

How Do Molecular Crowders Influence Ligand Binding Kinetics with G‑Quadruplex DNA? The Role of Bound Water by Parvez Alam (789093)

“…Experiments are conducted with and without 10% and 20% (w/v) ethylene glycol (EG), PEG200 and PEG6000 crowders. …”

How Do Molecular Crowders Influence Ligand Binding Kinetics with G‑Quadruplex DNA? The Role of Bound Water by Parvez Alam (789093)

“…Experiments are conducted with and without 10% and 20% (w/v) ethylene glycol (EG), PEG200 and PEG6000 crowders. …”

Engraftment and occlusion of a bioengineered tooth unit in a tooth loss model. by Masamitsu Oshima (214304)

“…<p>(A) Schematic representation of the protocol used to transplant a bioengineered tooth unit in a murine tooth loss model. …”

Figure 1 raw data by Urban Bezeljak (8372241)

“…(E) Activation delay Ti decreases with higher Rabex5:Rabaptin5 concentration. …”

Data Sheet 1_Human and predator presence shape diel activity of urban red squirrels.pdf by Sinah Drenske (13191534)

“…To do so, species may reduce total activity time by increasing activity peaks at specific moments or shifting activity times. We analyzed camera trap data from a citizen science project over four project phases, including spring and autumn before and during the SARS-CoV-2 lockdown, to understand the effects of human, pet (cat, dog), and predator (marten) presence on the activity patterns of urban red squirrels (Sciurus vulgaris; hereafter ‘squirrel’). …”

Image_5_Group ICA of wide-field calcium imaging data reveals the retrosplenial cortex as a major contributor to cortical activity during anesthesia.jpg by Alessandro Scaglione (10810689)

Table_5_Deficiency of Intellectual Disability-Related Gene Brpf1 Attenuated Hippocampal Excitatory Synaptic Transmission and Impaired Spatial Learning and Memory Ability.XLSX by Weiwei Xian (6171842)

Anisotropic Tuning of Graphite Thermal Conductivity by Lithium Intercalation by Xin Qian (714942)

“…In this work, the thermal conductivity of lithium–graphite intercalation compounds (Li_<i>x</i>C₆) is calculated using molecular dynamics simulations as a function of the amount of lithium intercalated. We found that intercalation of lithium has an anisotropic effect on tuning the thermal conductivity: the thermal conductivity in the basal plane decreases monotonically from 1232 W/m·K of pristine graphite to 444 W/m·K of the fully lithiated LiC₆, while the thermal conductivity along the <i>c</i>-axis decreases first from 6.5 W/m·K for graphite to 1.3 W/m·K for LiC₁₈ and then increases to 5.0 W/m·K for LiC₆ as the lithium composition increases. …”

Sbds mutants display ribosomopathy and SDS phenotypes. by Marina E. Tourlakis (751986)

“…<p><b>A,</b> Embryos with biallelic mutations in <i>Sbds</i> have decreased mass compared with littermate controls, **<i>P</i><4X10^-6. …”

The hypoxia inducible factor/erythropoietin (EPO)/EPO receptor pathway is disturbed in a rat model of chronic kidney disease related anemia by Daniel Landau (440830)

“…BM and proximal tibia EPOR were unchanged in C-A but decreased in CKD. Proximal tibial phospho-STAT5 increased after the EPO bolus in C but not in CKD.…”

Table_5_Bacillus subtilis forms twisted cells with cell wall integrity defects upon removal of the molecular chaperones DnaK and trigger factor.XLSX by Judith Matavacas (14429442)

Deep learning, 3D ultrastructural analysis reveals quantitative differences in platelet and organelle packing in COVID-19/SARSCoV2 patient-derived platelets by Sagar S. Matharu (17347369)

Image_5_Natural Compounds Tapinarof and Galactomyces Ferment Filtrate Downregulate IL-33 Expression via the AHR/IL-37 Axis in Human Keratinocytes.jpeg by Gaku Tsuji (11237318)

High-intensity light induces rod and cone cell death in <i>clrn1</i>^-/- zebrafish. by Hannah J. T. Nonarath (20861735)

“…Quantification of (h) WGA- and (i) PNA-positive outer segments along a 100 µm section of the central retina revealed a significant decrease in rod and cone outer segments in light-damaged <i>clrn1</i>^<i>-/-</i> zebrafish. …”

Table_1_Efficacy and safety of intranasal insulin on postoperative cognitive dysfunction in elderly patients after laparoscopic radical resection of colorectal cancer: a double-bli... by Hailong Zhang (398565)

“…</p>Conclusion<p>Intranasal insulin may decrease the risk of POCD and inhibit the elevated serum IL-6, TNF-α, and S100β levels in elderly patients after laparoscopic radical resection of colorectal cancer, which proves that intranasal insulin may be a promising therapeutic option for POCD.…”