Image_1_Residue Mutations in Murine Herpesvirus 68 Immunomodulatory Protein M3 Reveal Specific Modulation of Chemokine Binding.JPEG by Radka Šebová (6872960)

“…We found that the E70A mutation enhanced binding of M3 to CCL5 two-fold but had little effect on its binding to CXCL8. …”

Low-Order Scaling <i>G</i>₀<i>W</i>₀ by Pair Atomic Density Fitting by Arno Förster (8356044)

“…Despite these shortcomings, for subsets of medium and large molecules from the GW5000 database, the error of our approach using basis sets of TZ and augmented double-ζ (DZ) quality is decreasing with system size. On the augmented DZ level, we reproduce canonical, complete basis set limit extrapolated reference values with an accuracy of 80 meV on average for a set of 20 large organic molecules. …”

Activation of the LHb mediates the chronic stress–induced increase in NREM sleep duration. by Lu Huang (211625)

HSF2 is degraded during KSHV lytic reactivation. by Lorenza Cutrone (21144285)

Quinacrine modifies the <i>F. tularensis</i> MglA and SspA interaction in a bacterial two-hybrid system. by Algevis P. Wrench (276279)

“…<p>Transcription activation by the interaction between MglA and SspA from <i>F. tularensis</i> SCHU S4 decreases in the presence of quinacrine. …”

In Vitro Influence of Mycophenolic Acid on Selected Parameters of Stimulated Peripheral Canine Lymphocytes by Maciej Guzera (2636809)

“…The influence of MPA on apoptosis was dependent on the mechanism of cell activation and MPA concentration. MPA caused a decrease in the expression of lymphocyte surface antigens, CD3, CD8 and CD25. …”

Programmed Release METTL3-14 Inhibitor Microneedle Protects Myocardial Function by Reducing Drp1 m6A Modification-Mediated Mitochondrial Fission by Boyue Huang (17051857)

“…By employing hypoxia-ischemic and TGF-β1-induced fibrosis cell models, we found that METTL3-14 inhibition effectively decreased cardiomyocyte death through the reduction of mitochondrial fragmentation and inhibiting myofibrillar transformation. …”

The effects of activation of LHb–projecting vLGN/IGL neurons on NREM sleep. by Lu Huang (211625)

Autophagic homeostasis is required for the pluripotency of cancer stem cells by Tanveer Sharif (329961)

“…In this report, using both human and murine models of CSCs, we demonstrate that basal levels of autophagy are required to maintain the pluripotency of CSCs, and that this process is differentially regulated by the rate-limiting enzyme in the NAD⁺ synthesis pathway NAMPT (nicotinamide phosphoribosyltransferase) and the transcription factor POU5F1/OCT4 (POU class 5 homeobox 1). …”

Data_Sheet_1_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.DOCX by Ai Qing Yu (9774356)

“…Specifically, among the identified proteins, we found SIRT7 decrotonylated PHF5A, an alternative splicing (AS) factor, at K25. …”

Data_Sheet_2_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.XLS by Ai Qing Yu (9774356)

“…Specifically, among the identified proteins, we found SIRT7 decrotonylated PHF5A, an alternative splicing (AS) factor, at K25. …”

Data_Sheet_3_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.XLSX by Ai Qing Yu (9774356)

“…Specifically, among the identified proteins, we found SIRT7 decrotonylated PHF5A, an alternative splicing (AS) factor, at K25. …”

Birds invest wingbeats to keep a steady head and reap the ultimate benefits of flying together by Lucy A. Taylor (492318)

“…Despite this, no studies have quantified the biomechanical consequences of flying in a cluster flock or pair relative to flying solo. Here, we compared the flight characteristics of homing pigeons (<i>Columba livia</i>) flying solo and in pairs released from a site 7 km from home, using high-precision 5 Hz global positioning system (GPS) and 200 Hz tri-axial accelerometer bio-loggers. …”

Targeted genetic screening in mice through haploid embryonic stem cells identifies critical genes in bone development by Meizhu Bai (6905372)

“…Whereas <i>Rln1</i>^{<i>−/−</i>} mice exhibited small skeletal size only at birth, <i>Irx5</i>^{<i>−/−</i>} mice showed skeletal abnormalities both in postnatal and adult phases due to decreased bone mass and increased bone marrow adipogenesis. …”

The implementation process for the LCG. by Anna Ramö Isgren (16819339)

“…</p><p> Trial registration </p><p>The trial has been registered at <a href="https://www.clinicaltrials.gov" target="_blank">www.clinicaltrials.gov</a>: <a href="https://clinicaltrials.gov/ct2/show/NCT05560802" target="_blank">NCT05560802</a>.…”

Primary and secondary/exploratory outcomes. by Anna Ramö Isgren (16819339)

“…</p><p> Trial registration </p><p>The trial has been registered at <a href="https://www.clinicaltrials.gov" target="_blank">www.clinicaltrials.gov</a>: <a href="https://clinicaltrials.gov/ct2/show/NCT05560802" target="_blank">NCT05560802</a>.…”

GSH evokes increase in the extracellular GABA levels in chick retinal tissue and in mixed neuronal-glial cells in culture. by Hercules R. Freitas (3174633)

“…(E) Percentage of [³H] GABA release induced by 5mM GSH in mixed neuronal-glial cells is blocked by 100nM BBG. [³H] GABA was also released by L-aspartate as a positive control. …”

Binuclear Manganese Compounds of Potential Biological Significance. 1. Syntheses and Structural, Magnetic, and Electrochemical Properties of Dimanganese(II) and -(II,III) Complexes... by Lionel Dubois (1503907)

“…<b>1</b>(CH₃OH) crystallizes in the monoclinic system, space group <i>P</i>2₁/<i>c</i>, with <i>a</i> = 10.9215(6) Å, <i>b</i> = 20.2318(12) Å, <i>c</i> = 19.1354(12) Å, α = 90°, β = 97.5310(10)°, γ = 90°, <i>V</i> = 4191.7 ų, and <i>Z</i> = 4. …”

DRLE alleviated ISO-induced heart injury. by Lung-Shuo Wang (3391244)

Melittin and alamethicin induce calcein leakage. by Rianne Bartelds (1343631)