DataSheet_1_Isoliquiritigenin Derivative Regulates miR-374a/BAX Axis to Suppress Triple-Negative Breast Cancer Tumorigenesis and Development.zip by Fu Peng (1426402)

“…Recent studies suggest that isoliquiritigenin (ISL) can significantly suppress the growth, migration, and invasion of breast cancer cells. We previously synthesized ISL derivatives and found that 3′,4′,5′,4″-tetramethoxychalcone (TMC) inhibits TNBC cell proliferation to a greater degree than ISL. …”

Ratiometric Luminescent Sensor of Picric Acid Based on the Dual-Emission Mixed-Lanthanide Coordination Polymer by Liang Li (46069)

“…Powerful explosive sensors play a key role in public security and environmental protection. Herein, we report a series of isostructural lanthanide coordination polymers [Ln₂L_1.5(NMP)₂]<i>_n</i> (<b>LnL</b>: Ln = Eu, Gd, Tb, Dy, Ho, and Er; H₄L = [1,1′:4′,1″-terphenyl]-2′,4,4″,5′-tetracarboxylic acid; NMP = <i>N</i>-methyl-2-pyrrolidone) and mixed-Ln <b>LnL</b> (<b>Eu_<i>x</i>Tb_1–<i>x</i>L</b>, <b>Eu_<i>x</i>Gd_1–<i>x</i>L</b>, <b>Tb_<i>x</i>Gd_1–<i>x</i>L</b>, and <b>Eu_<i>x</i>Tb_{0.02–<i>x</i>}Gd_0.98L</b>). …”

Table_1_Intake of Lactobacillus paragasseri SBT2055 improves subjective symptoms of common cold during winter season in healthy adults: A randomized, double-blind, placebo-controll... by Eiji Kobatake (4020206)

“…</p>Materials and methods<p>In this randomized, double-blind, placebo-controlled, parallel-group comparative study, Japanese individuals aged 20–64 years were recruited. A total of 200 participants were randomly divided into two groups by an independent controller (LG2055 and placebo groups; 100 participants per group). …”

Depletion of RipA results in a reversible arrest in growth of <i>M. smegmatis.</i> by Erik C. Hett (244859)

“…Bacteria were visualized with a 100× objective. (D) Depletion strains of <i>M. smegmatis</i> grown on plates containing a gradient of inducer created by placing 10 µl of 10 ng/ml Tet on a paper disc in the center of the plate, resulting in a concentration of inducer highest at the middle of the plate and lowest at the edges. …”

Invasion into a fixated channel. by Jeremy Rothschild (17537752)

“…<b>(B)</b> The probability of a successful invasion as a function of the insertion location (<i>N</i> = 100). …”

Pictorial view of some highly poisonous plants based on their LD50 values and respondent scores. by Faisal Rasool (12530732)

Evaluation of insulin secretion ability. by Narumi Takahashi (5343218)

Table_1_The Diagnostic Potential of SHOX2 and RASSF1A DNA Methylation in Early Lung Adenocarcinoma.xlsx by Hong Gao (68166)

“…In both cohorts, SHOX2 expression increased and RASSF1A expression decreased in tumor samples. The promoter methylation level of SHOX2 and RASSF1A was significantly higher in tumor samples at stage I-II than that in normal samples. …”

Image_1_The Diagnostic Potential of SHOX2 and RASSF1A DNA Methylation in Early Lung Adenocarcinoma.tif by Hong Gao (68166)

“…In both cohorts, SHOX2 expression increased and RASSF1A expression decreased in tumor samples. The promoter methylation level of SHOX2 and RASSF1A was significantly higher in tumor samples at stage I-II than that in normal samples. …”

Image_2_The Diagnostic Potential of SHOX2 and RASSF1A DNA Methylation in Early Lung Adenocarcinoma.tif by Hong Gao (68166)

“…In both cohorts, SHOX2 expression increased and RASSF1A expression decreased in tumor samples. The promoter methylation level of SHOX2 and RASSF1A was significantly higher in tumor samples at stage I-II than that in normal samples. …”

Maternal liver changes due to STZ administration and pregnancy. by Narumi Takahashi (5343218)

Inhibition of PGAM5 and apoptosis prevented <i>T. spiralis</i> larval invasion of Caco-2 monolayer. by Qi Qi Lu (17721401)

Morphology of pancreatic islets. by Narumi Takahashi (5343218)

IHC protocol used in this study. by Narumi Takahashi (5343218)

“…Furthermore, the duodenum of STZ-pregnant mice exhibited increased gene expression of ligand-degradable IGFR2 and decreased expression of GLUT5 and GLUT12 (fructose and glucose transporters, respectively) compared to STZ-virgin mice. …”

List of primers used in this study. by Narumi Takahashi (5343218)

“…Furthermore, the duodenum of STZ-pregnant mice exhibited increased gene expression of ligand-degradable IGFR2 and decreased expression of GLUT5 and GLUT12 (fructose and glucose transporters, respectively) compared to STZ-virgin mice. …”

Table_1_MRE11A Polymorphisms Are Associated With Subclinical Atherosclerosis and Cardiovascular Risk Factors. A Case-Control Study of the GEA Mexican Project.DOCX by Gilberto Vargas-Alarcón (120733)

“…We analyzed five MRE11A gene polymorphisms in 386 individuals with subclinical atherosclerosis and 1093 healthy controls. …”

Image5_SGLT2 inhibitors suppress epithelial–mesenchymal transition in podocytes under diabetic conditions via downregulating the IGF1R/PI3K pathway.TIF by Ruixue Guo (6377939)

“…Additionally, SGLT2, IGF1R, phosphorylated PI3K, α-SMA, SNAI-1, and ZEB2 protein levels were increased in high glucose-stimulated human podocytes (HPC) and significantly decreased in dapagliflozin-treated (50 nM and 100 nM) or OSI-906-treated (inhibitor of IGF1R, 60 nM) groups. …”

Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes by Shiliang Li (298790)

“…The long-term antidiabetic efficacies of <b>5</b> (10 mg/kg, qw) were better than those of the once-weekly trelagliptin and omarigliptin, especially in decreasing the hemoglobin A1c level.…”

Table 5_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.xlsx by Lan Wang (85307)

“…This was also verified in MPC5 cells. By analyzing CLIP-seq and RNA-seq data, we found that hnRNP-F may inhibit gene expression by binding to lncRNA SNHG1. …”

Image 5_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.tif by Lan Wang (85307)

“…This was also verified in MPC5 cells. By analyzing CLIP-seq and RNA-seq data, we found that hnRNP-F may inhibit gene expression by binding to lncRNA SNHG1. …”