Data_Sheet_3_Thyroxine Induces Acute Relaxation of Rat Skeletal Muscle Arteries via Integrin αvβ3, ERK1/2 and Integrin-Linked Kinase.ZIP by Ekaterina K. Selivanova (11430214)

“…The effect of T4 on α₁-adrenergic contraction is stronger compared to T3 and involves the suppression of extracellular matrix signaling via integrin αvβ3, ERK1/2 and ILK with subsequent decrease of MLC2 (Ser19) phosphorylation.…”

DataSheet1_Remdesivir Strongly Binds to RNA-Dependent RNA Polymerase, Membrane Protein, and Main Protease of SARS-CoV-2: Indication From Molecular Modeling and Simulations.pdf by Faez Iqbal Khan (2884415)

“…In this study, we proposed that remdesivir strongly binds to membrane protein (Mprotein), RNA-dependent RNA polymerase (RDRP), and main protease (Mprotease) of SARS-CoV-2. …”

Table_1_MicroRNA-138-5p Suppresses Non-small Cell Lung Cancer Cells by Targeting PD-L1/PD-1 to Regulate Tumor Microenvironment.pdf by Nannan Song (5491205)

“…The regulatory mechanism of miR-138 in NSCLC remains not very clear. Herein, we demonstrated that miR-138-5p treatment decreased the growth of tumor cells and increased the number of tumor-infiltrated DCs. miR-138-5p not only down-regulated the expression of cyclin D3 (CCND3), CCD20, Ki67, and MCM in A549/3LL cells, but also regulated the maturation of DCs in A549-bearing nude mice and the 3LL-bearing C57BL/6 mouse model, and DCs’ capability to enhance T cells to kill tumor cells. …”

The dual CCR2/CCR5 chemokine receptor antagonist Cenicriviroc reduces macrophage infiltration and disease severity in Duchenne muscular dystrophy (Dmd^mdx-4Cv) mice by Feng Liang (447805)

“…Macrophage infiltration of dystrophic muscles has been strongly linked to muscle damage and fibrosis in DMD. We hypothesized that cenicriviroc (CVC), a dual chemokine receptor (CCR2/CCR5) antagonist currently under clinical evaluation for other diseases, could prevent macrophage accumulation and blunt disease progression in the diaphragms of mdx mice (genetic homologue of DMD). …”

Data_Sheet_1_Thyroxine Induces Acute Relaxation of Rat Skeletal Muscle Arteries via Integrin αvβ3, ERK1/2 and Integrin-Linked Kinase.PDF by Ekaterina K. Selivanova (11430214)

“…The effect of T4 on α₁-adrenergic contraction is stronger compared to T3 and involves the suppression of extracellular matrix signaling via integrin αvβ3, ERK1/2 and ILK with subsequent decrease of MLC2 (Ser19) phosphorylation.…”

Coenzyme Q Biosynthesis: Evidence for a Substrate Access Channel in the FAD-Dependent Monooxygenase Coq6 by Alexandre Ismail (847754)

“…In the yeast <i>Saccharomyces cerevisiae</i>, this putative flavin-dependent monooxygenase is proposed to hydroxylate the benzene ring of coenzyme Q (ubiquinone) precursor at position C5. We show here through biochemical studies that Coq6 is a flavoprotein using FAD as a cofactor. …”

Proteomic Profiling of the Acid Stress Response in <i>Lactobacillus plantarum</i> 423 by Tiaan Heunis (1754902)

“…<i>Lactobacillus plantarum</i> 423 tolerates acidic pH and is the ideal candidate in which to study molecular mechanisms that acid-tolerant lactic acid bacteria employ to survive such conditions. In this study we recorded changes in the protein profile of <i>L. plantarum</i> 423 when exposed to pH 2.5 by using a gel-free nanoLC–MS/MS proteomics approach. …”

Proteomic Profiling of the Acid Stress Response in <i>Lactobacillus plantarum</i> 423 by Tiaan Heunis (1754902)

“…<i>Lactobacillus plantarum</i> 423 tolerates acidic pH and is the ideal candidate in which to study molecular mechanisms that acid-tolerant lactic acid bacteria employ to survive such conditions. In this study we recorded changes in the protein profile of <i>L. plantarum</i> 423 when exposed to pH 2.5 by using a gel-free nanoLC–MS/MS proteomics approach. …”

Defects of neural tube and motoneuron formation in <i>dlx5a/6a</i> zebrafish morphants. by Nicolas Narboux-Neme (6482588)

“…The <i>dlx5a/6a</i> morphants show a reduced neural tube (A’-D’) associated with a defect of NCC migration (B’, black arrowhead), aberrant accumulation of <i>foxd3</i> and <i>ncad</i> transcripts in somites (B, D) and decrease of <i>msx1b</i> in the neural tube (F, black arrowhead). …”

<i>Galnt1</i> Is Required for Normal Heart Valve Development and Cardiac Function by E Tian (685836)

“…The underlying phenotype is aberrant valve formation caused by increased cell proliferation within the outflow tract cushion of developing hearts, which is first detected at developmental stage E11.5. Developing valves from <i>Galnt1</i> deficient animals displayed reduced levels of the proteases ADAMTS1 and ADAMTS5, decreased cleavage of the proteoglycan versican and increased levels of other extracellular matrix proteins. …”

S1 Dataset - by Yael Appelboom (20570815)

“…Mental effort rose from 17h onwards higher values, whereas a decrease in comfortability was seen from 21h onwards.…”

Characteristics of residents and shifts. by Yael Appelboom (20570815)

“…Mental effort rose from 17h onwards higher values, whereas a decrease in comfortability was seen from 21h onwards.…”

Types of decisions. by Yael Appelboom (20570815)

“…Mental effort rose from 17h onwards higher values, whereas a decrease in comfortability was seen from 21h onwards.…”

Data from: Developing a growing degree day model to guide integrated pest management of <i>Eucosma giganteana, </i>a pest of a novel perennial oilseed crop by HAZEL SCRIBNER (20664341)

“…Video was streamed live to a nearby laptop and captured with DinoCapture 2.0 (v.1.5.48.A, AnMo Electronics, New Taipei City, Taiwan). …”

S1 Data - by Angga Yudaputra (16792924)

“…We projected larger habitat loss in the SSP 5–8.5 compared to the SSP 1–2.6 climate change scenario.. …”

S2 Data - by Angga Yudaputra (16792924)

“…We projected larger habitat loss in the SSP 5–8.5 compared to the SSP 1–2.6 climate change scenario.. …”

Table 2_MiR-99a-5p up-regulates LDLR and functionally enhances LDL-C uptake via suppressing PCSK9 expression in human hepatocytes.docx by Xuemei Chen (14465)

“…Conversely, anti-miR-99a-5p upregulates PCSK9, leading to a reduction in LDLR, attenuation of LDL-C uptake, and a decrease in the intracellular cholesterol levels of human hepatocytes. …”

Table 1_MiR-99a-5p up-regulates LDLR and functionally enhances LDL-C uptake via suppressing PCSK9 expression in human hepatocytes.docx by Xuemei Chen (14465)

“…Conversely, anti-miR-99a-5p upregulates PCSK9, leading to a reduction in LDLR, attenuation of LDL-C uptake, and a decrease in the intracellular cholesterol levels of human hepatocytes. …”

Table 3_MiR-99a-5p up-regulates LDLR and functionally enhances LDL-C uptake via suppressing PCSK9 expression in human hepatocytes.docx by Xuemei Chen (14465)

“…Conversely, anti-miR-99a-5p upregulates PCSK9, leading to a reduction in LDLR, attenuation of LDL-C uptake, and a decrease in the intracellular cholesterol levels of human hepatocytes. …”

COVID-19 contact model. by Matteo Serafino (11599593)