Image 1_Myristic acid beneficially modulates intervertebral disc degeneration by preventing endplate osteochondral remodeling and vertebral osteoporosis in naturally aged mice.pdf by Yan Gong (103494)

“…Additionally, MA notably inhibited osteoclast activity, as evidenced by a decrease in the number of osteoclasts and a significant suppression of F-actin formation. …”

Structure-Directed Discovery of Potent Soluble Epoxide Hydrolase Inhibitors for the Treatment of Inflammatory Diseases by Yuanguang Chen (6835895)

“…Moreover the expression levels of sEH, COX-2, NOS-2, vascular cell adhesion molecule (VCAM), IL-6, MCP-5, and tumor necrosis factor α (TNF-α) were measured by Western blot or enzyme-linked immunosorbent assay (ELISA), with varying degrees of decrease. …”

Soluble plantain NSP increases the transmucosal short circuit current of <i>ex vivo</i> human ileal follicle-associated epithelium. by Bryony N. Parsons (469436)

“…<p>Plantain NSP (5 mg/mL) significantly increased (<b>A</b>) transmucosal short circuit current (<i>I_sc</i>), with a concomitant decrease in (<b>B</b>) epithelial potential difference (PD, apical-side negative), during pre-treatment of, and blockade of translocation of S. …”

Structure-Directed Discovery of Potent Soluble Epoxide Hydrolase Inhibitors for the Treatment of Inflammatory Diseases by Yuanguang Chen (6835895)

“…Moreover the expression levels of sEH, COX-2, NOS-2, vascular cell adhesion molecule (VCAM), IL-6, MCP-5, and tumor necrosis factor α (TNF-α) were measured by Western blot or enzyme-linked immunosorbent assay (ELISA), with varying degrees of decrease. …”

Structure-Directed Discovery of Potent Soluble Epoxide Hydrolase Inhibitors for the Treatment of Inflammatory Diseases by Yuanguang Chen (6835895)

“…Moreover the expression levels of sEH, COX-2, NOS-2, vascular cell adhesion molecule (VCAM), IL-6, MCP-5, and tumor necrosis factor α (TNF-α) were measured by Western blot or enzyme-linked immunosorbent assay (ELISA), with varying degrees of decrease. …”

Effect of the inhibition strength <i>β</i> on the cell cycle regulation in response to glucose fluctuation. by Yangjin Kim (191134)

“…When <i>β</i> is decreased (<i>β</i> = <i>β</i>_* → 0.07 in (A)) or increased (<i>β</i> = <i>β</i>_* → 2.0 in (C)) from the base value (<i>β</i>_* = 1.0), the system leads to G0-dominant and full cell cycle system, respectively. …”

Spiral wave dynamics in optogenetically-modified 2D human atrial tissue with uniform global sub-threshold illumination. by Rupamanjari Majumder (128411)

“…In (A) and (D), the light was applied for 5 s.</p>…”

Table_2_Sildenafil Alleviates Murine Experimental Autoimmune Encephalomyelitis by Triggering Autophagy in the Spinal Cord.doc by Eduardo Duarte-Silva (10795263)

“…Furthermore, decreased levels of LC3, beclin-1 and ATG5, suggests impaired autophagy, and decreased levels of AMPK in the spinal cord were also detected in EAE mice. …”

Table_1_Sildenafil Alleviates Murine Experimental Autoimmune Encephalomyelitis by Triggering Autophagy in the Spinal Cord.doc by Eduardo Duarte-Silva (10795263)

“…Furthermore, decreased levels of LC3, beclin-1 and ATG5, suggests impaired autophagy, and decreased levels of AMPK in the spinal cord were also detected in EAE mice. …”

The link between inter-individual behavioural differences and the use of environmental enrichment by zoo-housed, yellow-breasted capuchin (<i>Sapajus xanthosternos</i>) by Sergio Nogueira-Filho (10808859)

Oxidative Stress in Mammalian Cells Impinges on the Cysteines Redox State of Human XRCC3 Protein and on Its Cellular Localization by Pierre-Marie Girard (245425)

“…By non-reducing SDS-PAGE we show that many different oxidants induce hXRCC3 oxidation that is monitored in Chinese hamster ovarian (CHO) cells by increased electrophoretic mobility of the protein and in human cells by a slight decrease of its immunodetection. …”

Colombian Ocular Inflammatory Diseases Epidemiology Study (COIDES): Prevalence, Incidence, and Sociodemographic Characterization of Uveitis in Colombia, 2015-2020 by Gabriela Florez-Esparza (17404252)

Tuning Sodium Ion Conductivity in the Layered Honeycomb Oxide Na_3–<i>x</i>Sn_2–<i>x</i>Sb_<i>x</i>NaO₆ by Rebecca W. Smaha (1664833)

“…A decrease in layer stacking disorder is also observed. …”

Treatment of filarial infection is associated with significantly enhanced cytokine responses to TLR2 and TLR9 ligands in latent TB patients. by Subash Babu (129304)

Fig 2 - by Hannah J. Thomas (13730162)

“…Dotted lines represent previously reported clinically meaningful changes. A 5% decrease in weight (equating to 3.5 kg for our study participants) has been considered to be clinically meaningful [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0274082#pone.0274082.ref021" target="_blank">21</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0274082#pone.0274082.ref022" target="_blank">22</a>]. …”

Increased aerobic glycolysis in MADD fibroblasts and <i>xav</i> mutants. by Yuanquan Song (238595)

“…</b> qRT-PCR analyses of gene expression revealed increased expression of glycolytic enzymes <i>eno1</i>, <i>pgam1a</i>, <i>pgk1</i>, <i>pfkma</i>, and <i>fructose-biphosphate aldolase C</i> (<i>aldoc</i>) by 2.8, 2, 1.9, 1.8 and 2.1 fold respectively, as well a ∼20% decrease in <i>dihydrolipoamide S-acetyltransferase</i> (<i>dlat</i>), that belongs to the pyruvate dehydrogenase complex, which links glycolysis to tricarboxylic acid (TCA) cycle, in <i>xav</i> mutants compared to WT embryos at ∼56 hpf (N = 3–7 replicates, 20 embryos each; Student's t test, * p<0.05, ** p<0.01).…”

MAB21L2 wild-type and mutant protein studies. by Brett Deml (696234)

“…Please note the presence of wild-type MAB21L2 in both nuclear (N) and cytoplasmic (C) fractions (left), decreased expression of Arg51Gly and Arg51_Phe52del mutants (center) and the absence of Gln48* mutant protein (right; arrowhead indicates region corresponding to 5.5kDa, the predicted molecular weight for this peptide); predicted molecular weight for MAB21L2 is ~41kDa and for GAPDH is ~36 kDa; positions and corresponding molecular weights of protein ladder are shown for every blot. …”

Data_Sheet_1_Effect of Land Use History on Biodiversity of Pine Plantations.docx by Sandra V. Uribe (8575152)

Data_Sheet_1_DHCR24 Knock-Down Induced Tau Hyperphosphorylation at Thr181, Ser199, Thr231, Ser262, Ser396 Epitopes and Inhibition of Autophagy by Overactivation of GSK3β/mTOR Signa... by Xiaojing Bai (1661731)

“…In addition, to elucidate the association between DHCR24 and tauopathy, we further showed that the level of plasma membrane cholesterol, lipid raft-anchored protein caveolin-1, and concomitantly total I class PI3-K (p110α), phospho-Akt (Thr308 and Ser473) were significantly decreased, resulting in the disruption of lipid raft/caveola and inhibition of PI3-K/Akt signaling in silencing DHCR24 SH-SY5Y cells compared to control groups. …”

Table_1_Mass Drug Administration With Artemisinin-Piperaquine for the Elimination of Residual Foci of Malaria in São Tomé Island.DOCX by Mingqiang Li (512995)

“…The proportion of the P. falciparum malaria cases on the total malaria cases of the country decreased of 90.16% in zone A and 71.34% in zone C.…”