Integrated NMR interface and mutagenesis data illustrated onto the HPV16 E6 3D structure. by Katia Zanier (17371)

“…Side-chains that when mutated decrease E6/pep11** binding in mammalian two-hybrid assays by 1.5-fold or more (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0112514#pone-0112514-g005" target="_blank">Figure 5C</a>) are displayed.…”

Influence of Weeds on Yacon Initial Growth and Development by M.O. CABRAL (8492853)

Spatial changing of charged amino acids on HA epitopes in variants/vaccine strains. by Zhong-Zhou Huang (4248793)

“…<p>a. Charged amino acids of five epitopes on HA included, Epitope A labeled in blue (124, 133, 135, 142 and 145), B in red (155, 156, 158, 160, 189, 190, 193 and 197), C in green (50, 53, 275, 276, 278, 279, 307 and 310), D in yellow (172, 173, 201, 207, 208, 222, 225 and 246) and E in cyan (57, 62, 63, 75, 82, 83, 92 and 261)(a.i and a-ii). b. …”

Inhibition of human nSMase2 by cambinol and closely related analogs. by Mariana Figuera-Losada (744786)

“…<i>K</i>_m and <i>V</i>_max values decrease with increasing concentrations of inhibitor. …”

Image_3_Association of Dynamic Changes in Peripheral Blood Indexes With Response to PD-1 Inhibitor-Based Combination Therapy and Survival Among Patients With Advanced Non-Small Cel... by Yuzhong Chen (1556500)

“…The decrease or NLR at week 6 (OR = 3.081, 95%CI: 1.464-6.483) or 12 (OR = 3.304, 95%CI: 1.560-7.001) post-treatment, or CEA at week 12 post-treatment (OR = 2.469, 95%CI: 1.134-5.375), was associated with a higher objective response rate. …”

Image_2_Association of Dynamic Changes in Peripheral Blood Indexes With Response to PD-1 Inhibitor-Based Combination Therapy and Survival Among Patients With Advanced Non-Small Cel... by Yuzhong Chen (1556500)

“…The decrease or NLR at week 6 (OR = 3.081, 95%CI: 1.464-6.483) or 12 (OR = 3.304, 95%CI: 1.560-7.001) post-treatment, or CEA at week 12 post-treatment (OR = 2.469, 95%CI: 1.134-5.375), was associated with a higher objective response rate. …”

Table_1_Association of Dynamic Changes in Peripheral Blood Indexes With Response to PD-1 Inhibitor-Based Combination Therapy and Survival Among Patients With Advanced Non-Small Cel... by Yuzhong Chen (1556500)

“…The decrease or NLR at week 6 (OR = 3.081, 95%CI: 1.464-6.483) or 12 (OR = 3.304, 95%CI: 1.560-7.001) post-treatment, or CEA at week 12 post-treatment (OR = 2.469, 95%CI: 1.134-5.375), was associated with a higher objective response rate. …”

Table_1_Association of Dynamic Changes in Peripheral Blood Indexes With Response to PD-1 Inhibitor-Based Combination Therapy and Survival Among Patients With Advanced Non-Small Cel... by Yuzhong Chen (1556500)

“…The decrease or NLR at week 6 (OR = 3.081, 95%CI: 1.464-6.483) or 12 (OR = 3.304, 95%CI: 1.560-7.001) post-treatment, or CEA at week 12 post-treatment (OR = 2.469, 95%CI: 1.134-5.375), was associated with a higher objective response rate. …”

Image_1_Association of Dynamic Changes in Peripheral Blood Indexes With Response to PD-1 Inhibitor-Based Combination Therapy and Survival Among Patients With Advanced Non-Small Cel... by Yuzhong Chen (1556500)

“…The decrease or NLR at week 6 (OR = 3.081, 95%CI: 1.464-6.483) or 12 (OR = 3.304, 95%CI: 1.560-7.001) post-treatment, or CEA at week 12 post-treatment (OR = 2.469, 95%CI: 1.134-5.375), was associated with a higher objective response rate. …”

Table1_Exercise-Induced Atrial Remodeling in Female Amateur Marathon Runners Assessed by Three-Dimensional and Speckle Tracking Echocardiography.DOCX by Zofia Lasocka (12993621)

“…After the race, an increase in right ventricular (RV) dimensions (RV end-diastolic volume index, 48.8 ± 11.0 vs. 60.0 ± 11.1 ml/m²; p = 0.001) and a decrease in RV function (RV ejection fraction, 54.9 ± 6.3 vs. 49.1 ± 6.3%; p = 0.006) were observed. …”

Image_2_Association of Dynamic Changes in Peripheral Blood Indexes With Response to PD-1 Inhibitor-Based Combination Therapy and Survival Among Patients With Advanced Non-Small Cel... by Yuzhong Chen (1556500)

“…The decrease or NLR at week 6 (OR = 3.081, 95%CI: 1.464-6.483) or 12 (OR = 3.304, 95%CI: 1.560-7.001) post-treatment, or CEA at week 12 post-treatment (OR = 2.469, 95%CI: 1.134-5.375), was associated with a higher objective response rate. …”

Image_3_Association of Dynamic Changes in Peripheral Blood Indexes With Response to PD-1 Inhibitor-Based Combination Therapy and Survival Among Patients With Advanced Non-Small Cel... by Yuzhong Chen (1556500)

“…The decrease or NLR at week 6 (OR = 3.081, 95%CI: 1.464-6.483) or 12 (OR = 3.304, 95%CI: 1.560-7.001) post-treatment, or CEA at week 12 post-treatment (OR = 2.469, 95%CI: 1.134-5.375), was associated with a higher objective response rate. …”

Image_1_Association of Dynamic Changes in Peripheral Blood Indexes With Response to PD-1 Inhibitor-Based Combination Therapy and Survival Among Patients With Advanced Non-Small Cel... by Yuzhong Chen (1556500)

“…The decrease or NLR at week 6 (OR = 3.081, 95%CI: 1.464-6.483) or 12 (OR = 3.304, 95%CI: 1.560-7.001) post-treatment, or CEA at week 12 post-treatment (OR = 2.469, 95%CI: 1.134-5.375), was associated with a higher objective response rate. …”

Long-Term Assessment of Wild Boar Harvesting and Cattle Removal for Bovine Tuberculosis Control in Free Ranging Populations by Gregorio Mentaberre (293718)

“…We describe the first high-prevalence focus of TB in a non-managed wild boar population in northern Spain and the result of eight years of TB management. …”

Targeted deletion of PPARγin macrophages inhibits lung cancer metastasis in an orthotopic mouse model of non-small cell lung cancer. by Howard Li (194066)

“…Animals were injected with 10⁵ CMT/167-luc cells orthotopically as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0028133#pone-0028133-g001" target="_blank">Fig. 1</a>. …”

Theoretical model of the transcription cycle and experimental setup. by Jonathan Liu (769699)

“…Because elongation continues after initiation has ceased, the 5’ MS2 signal begins decreasing before the 3’ PP7 signal. …”

Liver-specific RORγ deficient mice exhibit improved insulin sensitivity and reduced gluconeogenesis. by Yukimasa Takeda (564952)

“…<p>(<b>A</b>) <i>RORγ</i> expression in liver and kidney collected from <i>RORγ^fx/fxAlb-Cre⁺</i> and -<i>Alb-Cre⁻</i> mice at ZT8 and ZT20 (n = 4–5). …”

SNX-1, IWN3* and RME-8 expression levels control RME-8 microdomain localization and positioning. by Anne Norris (268484)

“…Single channels and the merge are displayed, with an inset of an endosome from the merged channels. (G) Illustration of how to calculate the interior versus peripheral labeling of RME-8 (H) Quantification of the ratio of intensity of interior versus peripheral endosome labeling of RAB-5, RAB-7 (from <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010296#pgen.1010296.g002" target="_blank">Fig 2B and 2C</a>) and the indicated GFP::RME-8 allele from A-F<i>"</i> plotted on a Log2 scale. …”

Genetic Variants of Pregnane X Receptor (PXR) and CYP2B6 Affect the Induction of Bupropion Hydroxylation by Sodium Ferulate by Lichen Gao (423659)

“…<i>NR1I2</i> TGT haplotype (-25385T+g.7635G+g.8055T) carriers exhibited a significantly decreased AUC ratio, compared with TGT noncarriers, in the basal states (7.6±1.0 versus 9.7±1.0), while this result wasn't observed in <i>CYP2B6*6</i> noncarriers. …”

NIK is responsible for noncanonical NF-κB activation in ovarian cancer cell lines. by Masaya Uno (522188)

“…<p>(A) RMG-I and JHOC-5 cells were infected with lentivirus vectors expressing shRNA targeting <i>NIK</i> (shNIK-1) or <i>GFP</i> (shCtl). …”