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401
Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2.
Published 2018“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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402
The Structure of the Free Volume in Poly(styrene-co-acrylonitrile) from Positron Lifetime and Pressure Volume Temperature (PVT) Experiments
Published 2004“…The mean hole volume, vh, varies in PS between 105 Å3 (27 °C) and 220 Å3 (190 °C), and shows a systematic decrease with increasing AN content, at Tg from 121 Å3 for PS to 102 (±2) Å3 for SAN50. …”
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403
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404
Investigating the utilization of healthcare services to manage respiratory tract infections (RTIs) among Qatari patients attended selected primary healthcare centers in Qatar
Published 2018“…We have found no difference in the month-to-month rates of RTI-related GP visits (per 1000 total visits) over the study period (non-significant decreasing trend). …”
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405
STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
Published 2024“…This study investigates the impact of five pathogenic CBS missense mutations [c.1006C>T (p.R336C), c.689T>A (p.L230Q), 215A>T (p.K72I), c.707C>A (p.T236N), and c.457G>A (p.G153R)] identified in homocystinuria patients and appeared to be resistant to pyridoxine treatment on the biochemical and biophysical properties of CBS protein. …”
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406
Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
Published 2018“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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407
Flight Scheduling in the Airspace
Published 2016“…In this study, we developed a scatter search (SS) to deal with larger instances. …”
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408
Effect of Magnetic Baffles and Magnetic Nanofluid on Thermo-Hydraulic Characteristics of Dimple Mini Channel for Thermal Energy Applications
Published 2022“…The increment changed to 1.82%, 8.16%, and 22.31% for a pitch = 5 mm and 1.01%, 5.96%, and 21.38% for a pitch = 2.5 mm. …”
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409
Fabrication of Selective Sensors for Hg2+ Traces in Water Using Graphene Decorated with Metal Nanoclusters
Published 2016“…Two batches of sensors were tested in this work: i) sensors based on graphene only, and ii) sensors based on graphene and percolating films of Au nanoclusters, each has a thickness of 5 nm. For nanocluster deposition, each graphene sample was fixed on a cryostat finger. …”
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410
Effects of financial turmoil on financial integration and risk premia in emerging markets
Published 2016“…The aim of this article is to analyze how financial crises affect the dynamics of international financial integration and of the risk premia in emerging markets. Accordingly, we estimate a variant of the International Asset Pricing Model developed by Carrieri et al. (2007), allowing for time-varying stock market integration, in which we include the foreign currency risk. …”
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411
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412
Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia
Published 2016“…While neither glycine nor 5-Ala could ameliorate SLC25A38 congenital sideroblastic anemia in a zebrafish model, we determined that the addition of folate with glycine was able to restore hemoglobin levels. …”
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413
Use and assessment of “e-plastics” as recycled aggregates in cement mortar
Published 2019“…© 2019 Elsevier B.V. In this study we investigated the physical and mechanical properties of cement mortars, partially replaced with plastic (recycled plastic aggregate, RPA) recovered from WEEE (namely, “e-plastics”). …”
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414
Modification of Pd/CeO2 catalyst by Atomic Layer Deposition of ZrO2
Published 2016“…Methane-oxidation rates in 0.5% CH4 and 5% O2 were slightly lower on the ZrO2-covered catalyst when both materials were calcined at 673 K but the activity of the ZrO2-modified catalyst did not decrease with catalyst calcination temperature. …”
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415
Effect of serum lipoproteins on stereoselective halofantrine metabolism by rat hepatocytes
Published 2012“…Experimental hyperlipidemia has shown to decrease cytochrome P450 3A4 and 2C11 expression and to increase liver concentrations and the plasma protein binding of halofantrine (HF) enantiomers. …”
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416
Novel, selective EPO receptor ligands lacking erythropoietic activity reduce infarct size in acute myocardial infarction in rats
Published 2016“…In a pilot study, EPO at 100 U/mL significantly decreased cell death compared to vehicle (33.8 ± 2.3% vs. 40.3 ± 1.5%, p < 0.05) in rat neonatal cardiomyocytes subjected to simulated ischemia/reperfusion. …”
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417
Fluorinated Benzofuran and Dihydrobenzofuran as Anti-Inflammatory and Potential Anticancer Agents
Published 2023“…Targeting inflammation in cancer associated with chronic inflammation is a promising therapy. In the present study, we investigated the anti-inflammatory effects of fluorinated benzofuran and dihydrobenzofuran derivatives in macrophages and in the air pouch model of inflammation, as well as their anticancer effects in the human colorectal adenocarcinoma cell line HCT116. …”
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418
Detoxification assays of tunisian tannery wastewater under nonsterile conditions using the filamentous fungus aspergillus Niger
Published 2019“…Characterization of effluents also revealed high salt levels (EC > 17 mS/cm) and high organic matter content (25 g/L for the UE and 7.2 g/L for the FE) but a low biodegradability since BOD5 did not exceed 2.5 and 1.25 g/L for the UE and the FE, respectively. …”
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419
Study on adaptive thermal comfort in Japanese offices under various operation modes
Published 2017“…The lower and upper limits of the optimum comfort temperature is approximately 23.5C and 26.6C in mixed-mode. In addition, it is seen that the optimum comfort temperature tends to increase and decrease at very low and high outdoor air temperatures respectively. …”
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420
Optimal Energy Dispatch Engine for PV-DG-ESS Hybrid Power Plants Considering Battery Degradation and Carbon Emissions
Published 2023“…The test results revealed a 9.2% and 3.5% decrease in daily costs compared to the heuristic and stochastic methods, respectively, and a 29.4% decrease in carbon emission costs.…”
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