Data_Sheet_1_UGT1A1 Variants c.864+5G>T and c.996+2_996+5del of a Crigler-Najjar Patient Induce Aberrant Splicing in Minigene Assays.PDF by Linda Gailite (8539332)

“…Thus, the three anomalous transcripts are likely to inactivate UGT1A1. Moreover, this patient is also homozygous for the promoter variant A(TA)7TAA that decreases UGT1A1 expression by 70%, so the full-length transcript produced by c.864+5G>T would be even more reduced (<9%), thus supporting the diagnosis of CNS-type II. …”

S1 Data - by Toru Hosokawa (364158)

“…The bicaudate ratio increased in 38/58 (65.5%) patients, Evans index increased in 35/58 (60.3%) patients, and brain volume by volumetry decreased in 46/58 (79.3%) patients from the first to the second measurement, with significant increases in the bicaudate ratio (<i>P</i> < 0.0001) and Evans index (<i>P</i> = 0.0005) and a significant decrease in the brain volume by volumetry (<i>P</i> < 0.0001). …”

Plot of the density profiles in the (a) stable and (b) expansion regions for the potential (5) by J B Sudharsan (557453)

“…</strong> Plot of the density profiles in the (a) stable and (b) expansion regions for the potential (<a href="http://iopscience.iop.org/0953-4075/46/15/155302/article#jpb466473eqn05" target="_blank">5</a>).…”

Schematic diagram of the track and latch comparator (a) conventional track and latch comparator (b) small signal model of the comparator. by Labonnah Farzana Rahman (641767)

PM2.5 associates with blood pressure: a Mendelian randomization analysis by Minghui Bao (767132)

“…We conducted a two-sample Mendelian randomization (MR) analysis and identified 58 genome-wide significant single-nucleotide polymorphisms associated with PM2.5 as instrument variables. …”

Image_5_Identification of Sorafenib as a Treatment for Type 1 Diabetes.tif by Qin Zeng (166641)

Image5_A role for TRPC3 in mammalian testis development.jpg by Zhenhua Ming (5179547)

“…In this study, we describe a novel testicular target gene of SOX9, Trpc3. …”

Image5_A role for TRPC3 in mammalian testis development.TIF by Zhenhua Ming (5179547)

“…In this study, we describe a novel testicular target gene of SOX9, Trpc3. …”

Tunicamycin produces a concentration- and time-dependent decrease in cell viability in SH-SY5Y cells concomitant with caspase-3 activation. by Arindam P. Ghosh (317870)

“…<p>(A) Treatment of SH-SY5Y cells with tunicamycin (0.1–5µM) for 24 h caused a progressive decrease in cell viability as measured by Calcein AM cleavage assay. …”

Mitochondrial dysfunction is driven by decreased mitochondrial dynamics. by Piero Dalle Pezze (622889)

“…<p>(A) Sensitivity analysis averaged along the time course for the mitochondrial species in the model by varying the mitochondrial-related kinetic rate constant parameters. …”

Replacement of <i>RPL22B</i> promoter by the GAL promoter results in a decrease in alternative 5′-splice site usage. by Tadashi Kawashima (550396)

TR4 and TR9 decrease hepatoma cell viability at a lower TC50 than Sorafenib, SAHA or 5-Fluorouracil. by Nicole Lange (335740)

Binding sensogram (a) showing decrease in frequency of crystal immobilised with 1.5 M short aptamer exposed to different concentrations of heparanase. by Suzanne C. Simmons (319222)

“…<p>Higher concentrations of heparanase exhibited a greater decrease in frequency. Binding and regeneration sensogram (b) for addition of 800 nM heparanase to a quartz crystal immobilised with 1.5 M short aptamer. …”

Predicting alternans in the V_m-driven model during a progressive decrease of I_Ks conductance. by Mathieu Lemay (330649)

A new resource allocation model partitions the genome in five expression sectors. by Mónica Chagoyen (4253800)

“…<p><b>A)</b> Top. Resource allocation model (Model 1) based on three sectors in which the expression of their constituent genes increases (positive genes, blue), decreases (negative genes, red), or remains constant (invariant genes, brown) with increasing growth rate. …”

Stata code and data zip file. by Estefanía Custodio (131393)

“…Additionally, food sufficiency has markedly decreased, leading to an additional 5,000 households (3.3% of all households) experiencing inadequate daily calorie intake. …”

Comoros nutrients composition table. by Estefanía Custodio (131393)

“…Additionally, food sufficiency has markedly decreased, leading to an additional 5,000 households (3.3% of all households) experiencing inadequate daily calorie intake. …”

Methodological approach: General scheme. by Estefanía Custodio (131393)

“…Additionally, food sufficiency has markedly decreased, leading to an additional 5,000 households (3.3% of all households) experiencing inadequate daily calorie intake. …”

S1 File - by Yonghui Zhang (279832)

“…Different combinations of four observed phenological stages, including initial flowering, initial pod, initial grain, and initial maturity stages for five soybean cultivars from Exp. 1 and Exp. 3 described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0302098#pone.0302098.t002" target="_blank">Table 2</a> are respectively used to calibrate the CSPs. …”

A Diverse Family of Host-Defense Peptides (Piscidins) Exhibit Specialized Anti-Bacterial and Anti-Protozoal Activities in Fishes by Scott A. Salger (3072093)

“…Use of the innate immune system to decrease disease related mortalities is a novel alternative to conventional drugs. …”