These heatmaps indicate the number of mutations that accumulate after 5 passages in 5 insects, based on the predictions from the simulation model. by Dieke Boezen (12800457)

“…<p>For all simulations, we assumed a mutation rate similar to our estimated value for baculoviruses (<i>μ</i> = 10⁻⁷), and kept other model parameters the same as for model fitting (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009806#pgen.1009806.t004" target="_blank">Table 4</a>) unless otherwise indicated. …”

Skin defects in <i>Hdh</i>^neoQ50/<i>Hdh</i>^ex4/5 hypomorphic embryos. by Vidya Murthy (6495386)

“…<b>A)</b> At E18.5, following toluidine-blue dye exclusion assay, WT animal shows a functional epidermal barrier but <i>Hdh</i>^neoQ50/<i>Hdh</i>^ex4/5 animal has a compromised epidermal barrier on the ventral surface. …”

No effects of fingolimod on spinal cord glutamate transporter protein levels during EAE. by De-Hyung Lee (356687)

“…At the maximum of EAE, there was a decrease for SLC1A2 (A,B) and SLC1A3 protein levels (C,D) as compared to naïve mice which was restored after fingolimod treatment (3 mg/kg once daily). …”

Image5_Analysis of Geometric and Hemodynamic Profiles in Rat Arteriovenous Fistula Following PDE5A Inhibition.tif by Hannah Northrup (5938436)

“…In both groups: 1) CSA increased from the 0–5 to 15–20 zone; 2) velocity, WSS, and vorticity were highest in the 0–5 zone and dropped significantly thereafter; and 3) OSI increased at the 5–10 zone and then decreased gradually. …”

Raw data for No higher infectivity but immune escape of SARS-CoV-2 501Y.V2 variants by Qianqian Li (386223)

“…The susceptibility of 501Y.V2 variants to many neutralizing monoclonal antibodies decreased significantly. …”

Associations of Suboptimal Growth with All-Cause and Cause-Specific Mortality in Children under Five Years: A Pooled Analysis of Ten Prospective Studies by Ibironke Olofin (416327)

“…Mortality HR for severe wasting was 11.63 (9.84, 13.76) compared with 5.48 (4.62, 6.50) for severe stunting. Using older NCHS standards resulted in larger HRs compared with WHO standards. …”

Uncoupling protein-2 is an antioxidant that is up-regulated in the enamel organ of fluoride-treated rats by Maiko Suzuki (8794223)

“…Vitamin E is an antioxidant so we asked if a diet high in vitamin E would attenuate dental fluorosis. …”

Discovery of D25, a Potent and Selective MNK Inhibitor for Sepsis-Associated Acute Spleen Injury by Qiang Li (8118)

“…This study undertakes the modification of a 4-(3-(piperidin-4-yl)-1<i>H</i>-pyrazol-5-yl)pyridine structure, leading to the discovery of 4-(3-(piperidin-4-yl)-1<i>H</i>-pyrazol-5-yl)-1<i>H</i>-pyrrolo[2,3-<i>b</i>]pyridine (D25) as a potent and selective MNK inhibitor. …”

Impact of Dex on migration of triple negative and luminal BC cell lines <i>in vitro</i>. by Martin Crozier (13804275)

Table_5_Arabidopsis Histone Methyltransferase SUVH5 Is a Positive Regulator of Light-Mediated Seed Germination.DOCX by Dachuan Gu (6790856)

“…Loss of function of SUVH5 leads to decreased PHYB-dependent seed germination. …”

Table 5_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.xlsx by Yunyan Lu (10699005)

“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. …”

Image 5_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.pdf by Yunyan Lu (10699005)

“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. …”

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

Image_5_Immunogenicity of SARS-CoV-2 mRNA intramuscular vaccination in patients with muscular disorders.jpeg by Ryousuke Kasai (14577584)

“…The immunogenicity of SARS-CoV-2 vaccines against MDs, in particular, remains unknown. …”

Data_Sheet_1_Impact of Coinfection With SARS-CoV-2 and Influenza on Disease Severity: A Systematic Review and Meta-Analysis.docx by Zhou Guan (3723796)

“…<p>Background: Although coinfection with influenza in COVID-19 patients has drawn considerable attention, it is still not completely understood whether simultaneously infected with these two viruses influences disease severity. We therefore aimed to estimate the impact of coinfected with SARS-CoV-2 and influenza on the disease outcomes compared with the single infection of SARS-CoV-2.…”

CMS121 and C75 reduce the infectivity of HSV-1 viral particles. by Camilla Albano (16446679)

Spatial structure of the measurement area at the railway platform of Zürich Hardbrücke. by Mira Küpper (14797171)

The Natural Anticancer Agent Plumbagin Induces Potent Cytotoxicity in MCF-7 Human Breast Cancer Cells by Inhibiting a PI-5 Kinase for ROS Generation by Ju-Hee Lee (135452)

“…In MCF7 human breast cancer cells, plumbagin significantly decreased the level of a human ortholog, 1, 4-phopshatidylinositol 5-kinase (PI5K)-1B, of yeast its3, and knockdown of PI5K-1B using siPI5K-1B increased the ROS level and decreased cell viability. …”

Image_8_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a receptor 1(C5aR1) was significantly increased in skin lesions of both imiquimod (IMQ) and IL23-induced psoriatic mice and patients with psoriasis. …”