Epac activation increased RLC phosphorylation via PLC/PKC. by Yoshiki Ohnuki (576298)

(A) FC and VIP bubble chart of Model.vs.WKY comparison group; (B) Hierarchical clustering results of differential metabolites in Model.vs.WKY comparison group (only the top 50 VIP... by Xiao Zhang (152326)

Cooperativity increases with the expression level of CheW. by Stephan Eismann (835052)

<i>In vivo</i> anti-tumor efficacy of compound 4g (<i>N</i> = 6). by Min Xiao (320004)

Influence of nuclear proteins on the kinetics of unfolding of the h <i>c-myc</i> GQ structure, assayed by measuring the decrease in FRET activities in the presence of the complemen... by Anna Fekete (144891)

“…</p><p>F-<i>myc</i> GQ-R double labeled FRET oligonucleotide (25 pmol) was incubated either alone or with the tested proteins for one minute in a volume of 50 µl, than its FRET spectra was taken (0 min value). …”

Data Sheet 1_Brain microvascular endothelial cells differentiated from a Friedreich’s Ataxia patient iPSC are deficient in tight junction protein expression and paracellularly perm... by Frances M. Smith (17770776)

“…In the absence of dysregulated F-actin organization, FA iBMVEC exhibited a loss of 50% ZO-1, 63% Occludin, and 19% Claudin-5 protein expression, along with a disruption in the bi-cellular organization of the latter two proteins. …”

Apoptosis in thymus from cocaine-administered rats. by Kana Unuma (283272)

A PRISMA flowchart illustrated the selection of studies included in our systematic review. by Chenyi Ye (2697208)

Representative experimental samples. by Weisheng Zhao (3746023)

“…Based on the mechanical test results, reducing humidity can decrease the loss of uniaxial compressive strength (UCS) caused by moisture absorption from approximately 50% to 15.48%. …”

Mechanical testing apparatus and samples. by Weisheng Zhao (3746023)

“…Based on the mechanical test results, reducing humidity can decrease the loss of uniaxial compressive strength (UCS) caused by moisture absorption from approximately 50% to 15.48%. …”

Relationship between UCS, E, and water content. by Weisheng Zhao (3746023)

“…Based on the mechanical test results, reducing humidity can decrease the loss of uniaxial compressive strength (UCS) caused by moisture absorption from approximately 50% to 15.48%. …”

Hygroscopic experimental device. by Weisheng Zhao (3746023)

“…Based on the mechanical test results, reducing humidity can decrease the loss of uniaxial compressive strength (UCS) caused by moisture absorption from approximately 50% to 15.48%. …”

Nucleoid morphology disruption causes aberrant plasmid focus positioning. by Robert Ietswaart (676757)

“…<p>(<b>A</b>) Fluorescence localization of ParB-GFP (green) and Hoechst DNA stain (blue) in <i>mukE</i>, <i>mukF</i>, <i>matP</i> mutants and wild-type cells treated with 50 µg/ml nalidixic acid (Nal). …”

Data_Sheet_1_Complex CDKL5 translational regulation and its potential role in CDKL5 deficiency disorder.PDF by Valeria Ruggiero (631884)

“…By evaluating both cap-dependent and cap-independent translation initiation, we suggest the presence of an IRES supporting the translation of CDKL5 mRNA and propose a pathogenic effect of the C>T -189 SNP in decreasing the translation of the downstream protein.…”

Data_Sheet_2_Complex CDKL5 translational regulation and its potential role in CDKL5 deficiency disorder.pdf by Valeria Ruggiero (631884)

“…By evaluating both cap-dependent and cap-independent translation initiation, we suggest the presence of an IRES supporting the translation of CDKL5 mRNA and propose a pathogenic effect of the C>T -189 SNP in decreasing the translation of the downstream protein.…”

Flipping the Switch: Reverse-Demand Voltage-Sensitive Fluorophores by Jack T. McCann (13047830)

“…Our group has been developing voltage-sensitive fluorophores (VF dyes) that respond to changes in biological membrane potential (<i>V</i>_m). We hypothesize that the mechanism of voltage sensitivity arises from acceptor PeT (a-PeT) from an electron-rich aniline-containing molecular wire into the excited-state fluorophore, resulting in decreased fluorescence at negative <i>V</i>_m. …”

Robustness of results. by Raimundo Atal (18272064)

Genes in extracellular clusters E1-5. by Gareth A. Cromie (17118013)

“…We demonstrate that in the F13 genetic background deletions of transcription factors can either increase <i>(dig1</i>D, <i>sfl1</i>D) or decrease <i>(tec1</i>D) the degree of colony structure. …”

Supplementary Material for: Case fatality rates of subarachnoid hemorrhage are decreasing with substantial between-country variation: a systematic review of population-based studie... by Mahlamäki K. (13774423)

“…Since these same risk factors are linked to SAH mortality, the case fatality rate (CFR) of SAH has potentially also decreased during recent decades. Thus, we conducted a systematic review to address SAH CFR changes over the last 40 years. …”

table3_Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect After a Drug Repurposing Screen.pdf by Jordi Rodon (201558)

“…Here, we have screened existing drugs approved for human use in a variety of diseases, to compare how they counteract SARS-CoV-2-induced cytopathic effect and viral replication in vitro. …”