Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

“…In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”

Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

“…In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”

Multiomics of Colorectal Cancer Organoids Reveals Putative Mediators of Cancer Progression Resulting from SMAD4 Inactivation by Jelmer J. Dijkstra (14198102)

Multiomics of Colorectal Cancer Organoids Reveals Putative Mediators of Cancer Progression Resulting from SMAD4 Inactivation by Jelmer J. Dijkstra (14198102)

Multiomics of Colorectal Cancer Organoids Reveals Putative Mediators of Cancer Progression Resulting from SMAD4 Inactivation by Jelmer J. Dijkstra (14198102)

Discovery of NP3-742: A Structurally Diverse NLRP3 Inhibitor Identified through an Unusual Phenol Replacement by Juraj Velcicky (2201350)

Discovery of NP3-742: A Structurally Diverse NLRP3 Inhibitor Identified through an Unusual Phenol Replacement by Juraj Velcicky (2201350)

Discovery of NP3-742: A Structurally Diverse NLRP3 Inhibitor Identified through an Unusual Phenol Replacement by Juraj Velcicky (2201350)

Table_1_Immune responses in COVID-19 and tuberculosis coinfection: A scoping review.docx by Kevin Flores-Lovon (13432422)

“…Regarding patients with COVID-19 and active tuberculosis (aTB), they exhibited decreased total lymphocyte counts, CD4 T cells specific against SARS-CoV-2 and responsiveness to SARS-CoV-2 antigens compared to patients with only COVID-19.…”

Oct4 attenuates proliferation and migration while augments self-renewal in HPV16 CaSki cells. by Theofano Panayiotou (8721564)

DataSheet_1_BNT162b2 booster after heterologous prime-boost vaccination induces potent neutralizing antibodies and T cell reactivity against SARS-CoV-2 Omicron BA.1 in young adults... by Alina Seidel (13146438)

“…<p>In light of the decreasing immune protection against symptomatic SARS-CoV-2 infection after initial vaccinations and the now dominant immune-evasive Omicron variants, ‘booster’ vaccinations are regularly performed to restore immune responses. …”

Table_5_Preoperative Fasting C-Peptide Acts as a Promising Predictor of Improved Glucose Tolerance in Patients With Acromegaly After Transsphenoidal Surgery: A Retrospective Study... by Zihao Wang (845023)

“…</p><p>Methods: We retrospectively reviewed 64 patients who received transsphenoidal surgery for acromegaly. …”

Sample size by state in India in 2016 and 2021. by Anoop Jain (12095423)

Metabolic labelling of <i>P</i>. <i>falciparum</i> glycolipids with GDP-[^<i>3</i>H]-mannose. by Michaela S. Bulloch (19557058)

E03604: Sermon by Valerianus, bishop of Cimiez (southern Gaul), in praise of martyrdom and of the intercessory power of the saints, written in Latin at Cimiez in the mid 5th centur... by dlambert (10112257)

“…Who could doubt about the reward we have mentioned when he observes, lo, that the devotions of all men converge in loving the saints? …”

The Contrasting Role of p16^Ink4A Patterns of Expression in Neuroendocrine and Non-Neuroendocrine Lung Tumors: A Comprehensive Analysis with Clinicopathologic and Molecul... by Nicola Fusco (838180)

The TGF-β1/Smads signaling pathway and α-SMA expression levels in mice. by Lu Lin (201289)

AMPK Mediates Glucocorticoids Stress-Induced Downregulation of the Glucocorticoid Receptor in Cultured Rat Prefrontal Cortical Astrocytes by Shi-Ying Yuan (2937669)

“…In cultured rat cortical astrocytes, glucocorticoid treatment decreased the level, which was accompanied by the decreased expression of liver kinase B1 (LKB1) and reduced phosphorylation of AMPK. …”

Effect of phyllanthus niruri on metabolic parameters of patients with kidney stone: a perspective for disease prevention by Nidia D. Pucci (5631659)

“…There were no significant changes in all periods for anthropometric and several serum measurements, including total blood count, creatinine, uric acid, sodium, potassium, calcium, urine volume and pH; a significant increase in urinary potassium from 50.5±20.4 to 56.2±21.8 mg/24-hour (p=0.017); magnesium/creatinine ratio 58±22.5 to 69.1±28.6mg/gCr24-hour (p=0.013) and potassium/creatinine ratio 39.3±15.1 to 51.3±34.7mg/gCr24-hour (p=0.008) from baseline to wash out. …”

Sox2 direct interaction with mouse <i>Huwe1</i> and human <i>Huwe1</i> genes. by Yen-Fu Cheng (5819855)