PV1 treatment ameliorates EAU. by Pedro Henrique Papotto (791904)

Data_Sheet_1_Renal X-inactivation in female individuals with X-linked Alport syndrome primarily determined by age.PDF by Roman Günthner (8435811)

“…In other X-linked diseases, skewed X-inactivation leads to preferential silencing of one X-chromosome and thus can determine the phenotype in females. We aimed to show a correlation between X-inactivation in blood and urine-derived renal cells and clinical phenotype of females with a heterozygous disease-causing variant in COL4A5 compared to healthy controls. …”

Flowchart of the steps involved in the high-throughput exoproteome screening assay (HESA). by Marion Schoof (11999106)

Downregulation of TRIM37 expression exacerbates pathological damage in the MS model. by Lai Jiang (2401513)

“…Scale bar = 50 μm. (h) qRT-PCR (n = 6) and <b>(i, j)</b> Western blot (n = 3) both showed a significant decrease in the <i>TRIM37</i> mRNA and protein levels in the LPC-induced MS model compared to the control group. * <i><i>P</i></i> < 0.05, ** <i><i>P</i></i> < 0.01, *** <i><i>P</i></i> < 0.001, **** <i><i>P</i></i> < 0.0001, ns = not significant.…”

Fig 1B raw image. by Rachel K. Meade (22216529)

S1A Fig raw image. by Rachel K. Meade (22216529)

Further optimisation and <i>in vitro</i> characterization of influenza A reporter viruses. by Monique I. Spronken (779529)

“…Silent mutations were introduced into the PA packaging region present in the PA CDS (mPR) and the dPR was decreased from 149 to 50 nucleotides (sPR). (B) Virus titres of the wild-type and eGFP reporter viruses based on data from three individually rescued viruses. …”

Temsirolimus Partially Rescues the Hutchinson-Gilford Progeria Cellular Phenotype by Diana Gabriel (3608093)

“…The <i>LMNA</i> mutation results in the deletion of 50 amino acids from the carboxy-terminal region of prelamin A, producing the truncated, farnesylated protein progerin. …”

Illustrations of the SeqFold2D network and the Stralign dataset. by Xiangyun Qiu (316117)

Quercetin inhibited ERS and mitigated HG+OGD/R treated HT22 injury through activating SIRT1 and suppressing PERK signaling. by Jing Yang (13969)

Overexpression <i>TRIM37</i> inhibits inflammatory infiltration and alleviates demyelination in EAE model mice. by Lai Jiang (2401513)

Transcriptional changes detected in fecal RNA of neonatal dairy calves undergoing a mild diarrhea are associated with inflammatory biomarkers by Fernanda Rosa (4801314)

“…A time effect was observed for the cell membrane sodium-dependent glucose transporter <i>SLC5A1</i>, for the major carbohydrate facilitated transporter <i>SLC2A2</i>, and water transport function <i>AQP3</i>, where <i>SLC5A1</i> and <i>AQP3</i> had a negative quadratic effect over time. …”

A Novel PROTAC G9a/GLP Degrader that Inhibits, Similar to G9a siRNA, the Migration of MCF‑7 Breast-Cancer Cells without Affecting Proliferation by Anirban Mukherjee (103177)

Dopamine D₃/D₂ Receptor Ligands Based on Cariprazine for the Treatment of Psychostimulant Use Disorders That May Be Dual Diagnosed with Affective Disorders by Emma S. Gogarnoiu (13206131)

“…Cariprazine and two lead analogues, <b>13a</b> and <b>13e</b>, decreased cocaine self-administration (FR2; 1–10 mg/kg, i.p.) in rats, suggesting that partial agonists/antagonists with modest D₃R/D₂R selectivity may be effective in treating PSUD and potentially comorbidities with other affective disorders.…”

Column-based Technology for CD9-HPLC Immunoaffinity Isolation of Serum Extracellular Vesicles by Jianhui Zhu (678784)

“…The CD9-HPLC-IAC method achieved EV isolation from 40 μL of serum in 30 min with a yield of 8.0 × 10⁹ EVs, where EVs were further processed with a postcolumn cleaning step using the 50 kDa molecular weight cut-off filter for the buffer exchange, concentration, and reduction of potentially coeluting serum proteins. …”

Engineering Two-Dimensional Mass-Transport Channels of the MoS₂ Nanocatalyst toward Improved Hydrogen Evolution Performance by Ge Wang (56838)

“…Because of the engineering of nanostructured channels, a reduction in overpotential by approximately 100 and 360 mV at −10 and −100 mA cm^–2, respectively, a decrease in the Tafel slope from 66.7 to 39.4 mV dec^–1, and a more stable operation can be achieved. …”

Table_1_COVID-19 Vaccine Acceptance Among Dental Professionals Based on Employment Status During the Pandemic.XLSX by Asaf Zigron (10118963)

“…Dental professionals are uniquely exposed to environments with high levels of occupational hazards, conferring additional risks of viral exposure and transmission. We analyzed 506 anonymous questionnaires completed by dentists and residents regarding acceptance of a future potential SARS-CoV-2 vaccine. …”

Raw data for male activity. by Jessie E. Landis (16378731)

“…To determine which subset of neurons is implicated in this life span extension, we used the GAL4/UAS system to activate RNAi against genes of Complex I and Complex V. …”

Raw data for female fertility. by Jessie E. Landis (16378731)

“…To determine which subset of neurons is implicated in this life span extension, we used the GAL4/UAS system to activate RNAi against genes of Complex I and Complex V. …”

Raw data for male sleep. by Jessie E. Landis (16378731)

“…To determine which subset of neurons is implicated in this life span extension, we used the GAL4/UAS system to activate RNAi against genes of Complex I and Complex V. …”