Wnt8a mutations affect cell-non-autonomous activation of β-catenin and secretion. by Marta Luz (508403)

“…Secretion of mutant Wnt8a-GFP proteins is decreased compared to WT Wnt8a-GFP (G). β-catenin in shown in grey (A–F), GFP (green) and β-catenin (red) staining is shown merged (A′–F′). …”

Supplementary Material for: Correlation between the Incidence and Attributable Mortality Fraction of Acute Kidney Injury: A Systematic Review by Komaru Y. (6287003)

“…Both more recent publications and higher GDP countries had a lower crude AKI patients’ mortality, although AKI-attributable fraction did not decrease. …”

Antiarrhythmic Hit to Lead Refinement in a Dish Using Patient-Derived iPSC Cardiomyocytes by John R. Cashman (354526)

“…This resulted in compounds with decreased AP prolongation effects, increased metabolic stability, increased I_NaL selectivity, and decreased avidity for the potassium channel. …”

SPARC Regulates Transforming Growth Factor Beta Induced (TGFBI) Extracellular Matrix Deposition and Paclitaxel Response in Ovarian Cancer Cells by David A. Tumbarello (680437)

“…We determined that suppression of SPARC expression by shRNA decreased the deposition of TGFBI in mesothelial-derived ECM, without affecting its overall protein expression or secretion. …”

Transcriptional control in embryonic Drosophila midline guidance assessed through a whole genome approach-0 by Tiago R Magalhães (76330)

Cragg-Donald F statistics for instrument sets. by Daniel Hui (4418287)

“…In univariable analysis, we confirmed that a one standard deviation decrease in height (~6.5 cm) was associated with a 12.0% increase in the risk of CAD, consistent with previous reports. …”

Certain bacterial families have a greater tendency to transgress mucosal barriers and colonize submucosal tissues. by Rodrick J. Chiodini (776723)

“…<i>Legend</i>: Bacteria present in less than 50% of patients are excluded. All increases/decreases were statistically significant (p = <0.05) except as noted with an asterisk (*) in which p = >0.05 but <0.065 suggesting a trend toward statistical significance.…”

Rescue the Failed Half-ZFN by a Sensitive Mammalian Cell-Based Luciferase Reporter System by Weifeng Zhang (134361)

“…Lastly, site-specific genome editing by hPGRN ZFNs generated by this system was confirmed by sequencing, and the PGRN knock-out cell line showed significantly decreased cell growth compared with the control. Our system will provide a valuable tool for further optimizing the nucleases with regard to specificity and cytotoxicity.…”

Use of Thiopurines and Risk of Colorectal Neoplasia in Patients with Inflammatory Bowel Diseases: A Meta-Analysis by Jianfeng Gong (177593)

“…The use of thiopurines was associated with a statistically significant decreased incidence of colorectal neoplasm (summary RR=0.71, 95% CI=0.54–0.94, p=0.017), even after adjustment for duration and extent of the disease, but there was high heterogeneity among studies (<i>I</i>²=68.0%, p<0.001). …”

Prof A.Maleki_Figure 2_ESM from Green and efficient three-component synthesis of 4H-pyran catalysed by CuFe₂O₄@starch as a magnetically recyclable bionanocata... by Maryam Kamalzare (9016031)

A reduction in brain mass and cortical volume seen in the adult <i>Cln6^nclf</i> mouse. by Jeremy P. Morgan (479017)

S1 Data - by Yong Liu (6908)

“…This effect was partially reversed by inhibiting hsa-let-7e-5p. Furthermore, we found that overexpression of UBQLN4 counteracted the effects of hsa-let-7e-5p, suggesting UBQLN4 as a downstream mediator of hsa-let-7e-5p. …”

The influence of abrupt increases in seawater <i>p</i>CO₂ on plankton productivity in the subtropical North Pacific Ocean by Donn A. Viviani (5142383)

“…<div><p>We conducted a series of experiments to examine short-term (2–5 days) effects of abrupt increases in the partial pressure of carbon dioxide (<i>p</i>CO₂) in seawater on rates of primary and bacterial production at Station ALOHA (22°45’ N, 158° W) in the North Pacific Subtropical Gyre (NPSG). …”

Edge-Reconstructed, Few-Layered Graphene Nanoribbons: Stability and Electronic Properties by Juliana A. Gonçalves (3813442)

“…We find that the nanoribbon stability increases linearly with increasing width and decreases linearly with increasing number of layers (from three to six layers). …”

Electric field-navigated transcranial magnetic stimulation for chronic tinnitus: a randomized, placebo-controlled study by Hanna Sahlsten (3930824)

“…<i>Study sample:</i> Thirty-nine patients (mean age 50.3 years). <i>Results</i>: The mean tinnitus intensity (<i>F</i>₃ = 15.7, <i>p</i> < 0.0001), annoyance (<i>F</i>₃ = 8.8, <i>p</i> = 0.0002), distress (<i>F</i>₃ = 9.1, <i>p</i> = 0.0002) and THI scores (<i>F</i>₄ = 13.8, <i>p</i> < 0.0001) decreased in both groups over time with non-significant differences between the groups. …”

Data_Sheet_1_Experimental Induction of Micro- and Macrosomatognosia: A Virtual Hand Illusion Study.PDF by David Anders (10717857)

“…Virtual hand embodiment was explicitly and implicitly assessed by means of self-report and EDA analysis. Questionnaire results revealed a stable SoA across all hand size conditions, while SoO parametrically decreased according to the hand scaling factor in either direction. …”

Side-Chain and Ring-Size Effects on Permeability in Artificial Water Channels by Tyler J. Duncan (20494676)

“…We observe that water permeability decreases as a function of increasing ring-size due to increases in hydrophilic contacts between the permeating water-wire and the oxygen groups on the channel wall. …”

Effects of Probucol on Restenosis after Percutaneous Coronary Intervention: A Systematic Review and Meta-Analysis by Jichen Liu (727829)

“…Major outcome, binary angiographic restenosis defined as >50% stenosis upon follow-up angiography, was significantly decreased with probucol treatment (RR = 0.59 [0.43, 0.80] among vessels, P = 0.0007; and RR = 0.52 [0.40, 0.68] among patients, P<0.00001). …”

The Cysteine-Rich Protein Thimet Oligopeptidase as a Model of the Structural Requirements for S-glutathiolation and Oxidative Oligomerization by Alberto Malvezzi (155925)

“…Previous work on this enzyme revealed that the oxidative oligomerization of EP24.15 is triggered by S-glutathiolation at physiological GSSG levels (10–50 µM) via a mechanism based on thiol-disulfide exchange. …”

A Biomimetic Interface with High Adhesion, Tailorable Modulus for On-Skin Sensors, and Low-Power Actuators by Song Chen (69646)

“…By adopting this interface, we successfully fabricate a soft (skin-like modulus 0.1–10.0 MPa), ultrathin (∼50 μm), self-adhesive, and skin-compliant sensor. …”