Neuroprotection and immunomodulation by dimethyl fumarate and a heterologous fibrin biopolymer after ventral root avulsion and reimplantation by Paula R. G. Kempe (10411064)

“…Results: Treatment with DMF at a dose of 15 mg/kg was found to be neuroprotective and immunomodulatory because it preserved motoneurons and synapses and decreased astrogliosis and microglial reactions, as well as downregulated the expression of pro-inflammatory gene transcripts. …”

Table_1_Suicide risk among female breast cancer survivors: A population–based study.docx by Jian Shi (141852)

“…A nomogram was constructed to predict the suicide probability for individual survivors with a C-index of 0.62 (95%CI: 0.59-0.66).…”

Image_1_Suicide risk among female breast cancer survivors: A population–based study.tif by Jian Shi (141852)

“…A nomogram was constructed to predict the suicide probability for individual survivors with a C-index of 0.62 (95%CI: 0.59-0.66).…”

Image_2_Suicide risk among female breast cancer survivors: A population–based study.tif by Jian Shi (141852)

“…A nomogram was constructed to predict the suicide probability for individual survivors with a C-index of 0.62 (95%CI: 0.59-0.66).…”

Sensitivity analysis reveals a unique contribution for all damage mechanisms, but simulated tissue is most sensitive to oxygen. by Cordelia Ziraldo (221649)

“…<p>(<b>A</b>) We partitioned parameter values according to which damage mechanism they affected. …”

Investigating the effect of the air inlet temperature on the combustion characteristics of a spark ignition engine fueled by biogas by Ebrahemi, Abdullah Ebrahem

“…The effect of varying the air manifold temperature from 25 to 50°C on the combustion characteristics as well as engine performance under full load condition in a SI engine fueled by gasoline and biogas mixtures has been investigated. …”
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The Number of Patients and Events Required to Limit the Risk of Overestimation of Intervention Effects in Meta-Analysis—A Simulation Study by Kristian Thorlund (149383)

“…For each scenario, we calculated the probability of observing overestimates of RRR>20% and RRR>30% for each cumulative 500 patients and 50 events. …”

Diagnostic Algorithm for Glycogenoses and Myoadenylate Deaminase Deficiency Based on Exercise Testing Parameters: A Prospective Study by Fabrice Rannou (775170)

“…The lactate/rest ratio at the 10th minute of recovery from exercise displayed the best AUC (1.0) for discriminating between Decreased and Absent MAD activities. The resulting decision tree achieved a diagnostic accuracy of 86.3%.…”

Impact of etonogestrel implant use on T-cell and cytokine profiles in the female genital tract and blood by Lisa B. Haddad (8124953)

“…The percentage of CVL CD4+, CCR5+ HIV target cells expressing activation markers after implant placement was either reduced (HLA-DR+, p = 0.01) or unchanged (CD38+, p = 0.45). …”

Table_1_Plantain flour: A potential anti-obesity ingredient for intestinal flora regulation and improved hormone secretion.DOCX by Jinfeng Fu (10039190)

“…The male SD rats were divided into six groups, viz. two control groups [non-obese (NC) or obese (OC)] which were not given the supplementation, one positive control (PC) group which received orlistat supplementation (60 mg/kg body weight/day), and three groups of obese rats which were supplemented with unripe plantain flour (UPF) at a dosage (body weight/day) of 1.25 g/kg (low-dose, LD), 2.50 g/kg (intermediate-dose, MD) or 5.0 g/kg (high-dose, HD).…”

Impact of the Lab-Score on Antibiotic Prescription Rate in Children with Fever without Source: A Randomized Controlled Trial by Laurence Lacroix (673501)

“…<div><p>Background</p><p>The Lab-score, based on the combined determination of procalcitonin, C-reactive protein and urinary dipstick results, has been shown accurate in detecting serious bacterial infections (SBI) in children with fever without source (FWS) on retrospective cohorts. We aimed to prospectively assess the utility of the Lab-score in safely decreasing antibiotic prescriptions in children with FWS and to determine its diagnostic characteristics compared to common SBI biomarkers.…”

<i>Operando</i> Particle-Scale Characterization of Silicon Anode Degradation during Cycling by Ultrahigh-Resolution X‑ray Microscopy and Computed Tomography by Paul Choi (1762975)

“…At low rate cycling, the X-ray signal attenuation over the Si particles decreased with increased lithiation. In contrast, at high rate cycling, we observe increased attenuation at the electrode scale. …”

<i>Operando</i> Particle-Scale Characterization of Silicon Anode Degradation during Cycling by Ultrahigh-Resolution X‑ray Microscopy and Computed Tomography by Paul Choi (1762975)

“…At low rate cycling, the X-ray signal attenuation over the Si particles decreased with increased lithiation. In contrast, at high rate cycling, we observe increased attenuation at the electrode scale. …”

<i>Operando</i> Particle-Scale Characterization of Silicon Anode Degradation during Cycling by Ultrahigh-Resolution X‑ray Microscopy and Computed Tomography by Paul Choi (1762975)

“…At low rate cycling, the X-ray signal attenuation over the Si particles decreased with increased lithiation. In contrast, at high rate cycling, we observe increased attenuation at the electrode scale. …”

<i>In Vivo</i> Substrates of the Lens Molecular Chaperones αA-Crystallin and αB-Crystallin by Usha P. Andley (354477)

“…The amount of degraded glutamate dehydrogenase, α-enolase, and cytochrome c increased more than 50-fold in homozygous αA-R49C mutant lenses. In αB-R120G mouse lenses, our analyses identified decreased abundance of phosphoglycerate mutase, several β- and γ-crystallins, and degradation of αA- and αB-crystallin early in cataract development. …”

Ca²⁺ signalling and mitochondrial physiology defects in cells lacking anxA6. by Marcin Chlystun (288876)

“…(C) ΔΨm in <i>AnxA6</i>^+/+ and <i>AnxA6</i>^−/− ear fibroblasts was measured in cells equilibrated with 50 nM TMRM under resting conditions. …”

Sensitivity of various GFP insertion constructs (<i>columns A through J</i>) to protein misfolding. by Stéphanie Cabantous (92574)

“…<p>(A) Images of <i>E. coli</i> cells on plates expressing four test fusions proteins with decreasing folding robustness at 37°C. …”

Dynamic profiles of the prototypic integrated system under different conditions, and a comparison to the kinetic-based model. by Jong Min Lee (271984)

“…<p>The concentration of carbon and amount of biomass within the cellular system over a simulation time of 10 h is illustrated. The decreasing lines represent the concentration of carbon (as indicated by the left <i>y</i>-axis), which is being consumed, in the system. …”

A mutation in the <i>CACNA1C</i> gene leads to early repolarization syndrome with incomplete penetrance: A Chinese family study by Xin Liu (43569)

“…</p><p>Methods and results</p><p>We described a large Chinese family with nocturnal sudden cardiac death induced by ERS in most of the young male adults. …”

The impact of improved detection and treatment of isoniazid resistant tuberculosis on prevalence of multi-drug resistant tuberculosis: A modelling study by Kamila Romanowski (6260870)

“…</p><p>Conclusion</p><p>Accurate diagnosis and tailored treatment of INHR-TB with LPA led to an almost 50% relative decrease in acquired MDR-TB when compared with an Xpert MTB/RIF strategy. …”