Protein levels of Bcl-2 family markers in limbal stromal cells (LSCs) and in Aniridia-LSCs (AN-LSCs), after treatment with 0 µM, 50 µM and 75 µM Cobalt chloride (CoCl₂),... by Shanhe Liu (5251313)

Data_Sheet_1_Herpes Simplex Virus 1 UL2 Inhibits the TNF-α–Mediated NF-κB Activity by Interacting With p65/p50.pdf by Mingsheng Cai (286548)

“…<p>Herpes simplex virus 1 (HSV-1) is a large double-stranded DNA virus that encodes at least 80 viral proteins, many of which are involved in the virus–host interaction and are beneficial to the viral survival and reproduction. …”

Image 5_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff by Tien Le (634791)

Csf1r and Mer expression further define KC subsets in mouse liver. by Juan A. Santamaria-Barria (6655667)

Csf1r or Mer inhibition delays liver regeneration via suppression of Kupffer cells by Juan A. Santamaria-Barria (6655667)

“…At 36h after PH, Csf1r inhibition increased serum ALT and histological liver injury, and decreased liver cell proliferation. A small molecule inhibitor of Mer did not alter the percentage of KCs or their proliferation and just modestly delayed LR. …”

Data obtained from monitoring patients. by Ana Gabriela Gomes Ferrari Strang (17068913)

“…Three decreasing values of immunoglobulin G were a security parameter for stopping the child’s medication in the exposed group (50/61). …”

General characteristics and statistical analysis. by Ana Gabriela Gomes Ferrari Strang (17068913)

“…Three decreasing values of immunoglobulin G were a security parameter for stopping the child’s medication in the exposed group (50/61). …”

Csf1r inhibition, Mer inhibition, and clodronate liposomes have distinct biologic effects. by Juan A. Santamaria-Barria (6655667)

Patients outcome. by Loïc Duron (6433634)

“…Final visual acuity improved (median 2.0 vs 2.6 logMAR; p < 0.01), while cumulative intravenous corticosteroid exposure was significantly reduced (1679 ± 760 mg vs 2295 ± 1055 mg; p = 0.02). Reliance on temporal-artery biopsy fell (17% vs 91%; p < 0.01), owing to a four-fold rise in diagnostic MRI use. …”

A proposed model of the equilibrium between vesicular and surface-localized AQP5. by Philip Kitchen (827054)

“…<p>Panel A shows wild-type AQP5 under isotonic conditions. The large arrows represent an increase in AQP5 translocation (and the small arrows are a decrease). …”

Intravital 2-photon microscopy imaging of acute <i>C</i>. <i>albicans</i> infections of the kidney in real time in a living host. by Fitz Gerald S. Silao (9384713)

S2 File - by Alejandro Valencia (16007329)

“…Using the RAMP Hybrid method, we estimate 264,516 [95% confidence interval [CI], 223,506–307,577] premature deaths attributable to PM_2.5 from all sources, a ~1% overall decrease in CMAQ-estimated premature mortality compared to RAMP Hybrid, despite increases and decreases in some locations. …”

Minimal dataset. by Lilishia Gounder (15240167)

“…We obtained 7,639,978 HIV VL records from 736 healthcare facilities across KZN, of which 1,031,171 (13.5%) had detectable VLs (i.e., VLs ≥400 copies/millilitre (mL)). …”

Baseline characteristics with participants divided into groups according to quartiles of BMD at calcaneus and femoral neck. by Hans Lundin (800973)

Photodecomposition and Morphology Evolution of Organometal Halide Perovskite Solar Cells by Fukashi Matsumoto (1420882)

Cardiac Contractility Structure-Activity Relationship and Ligand-Receptor Interactions; the Discovery Of Unique and Novel Molecular Switches in Myosuppressin Signaling by Megan Leander (459603)

“…Further, these motifs were present in red flour beetle, common water flea, honey bee, domestic silkworm, and termite MS-Rs. RhpMS and DrmMS decreased <i>R</i>. <i>prolixus</i> cardiac contractility dose dependently with EC₅₀ values of 140 nM and 50 nM. …”

Identification of a Hydroxypyrimidinone Compound (<b>21</b>) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure by Wei Meng (505670)

“…Due to the increased polarity at C2, the permeability for these compounds decreased. Further adjustment of the polarity by replacing the N1 2,6-dimethoxyphenyl group with a 2,6-diethylphenyl group and reoptimization for the potency of the C5 pyrroloamides resulted in potent compounds with improved permeability. …”

Identification of a Hydroxypyrimidinone Compound (<b>21</b>) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure by Wei Meng (505670)

“…Due to the increased polarity at C2, the permeability for these compounds decreased. Further adjustment of the polarity by replacing the N1 2,6-dimethoxyphenyl group with a 2,6-diethylphenyl group and reoptimization for the potency of the C5 pyrroloamides resulted in potent compounds with improved permeability. …”

Identification of a Hydroxypyrimidinone Compound (<b>21</b>) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure by Wei Meng (505670)

“…Due to the increased polarity at C2, the permeability for these compounds decreased. Further adjustment of the polarity by replacing the N1 2,6-dimethoxyphenyl group with a 2,6-diethylphenyl group and reoptimization for the potency of the C5 pyrroloamides resulted in potent compounds with improved permeability. …”

Supplementary Material for: Inter-α-Trypsin Inhibitor Heavy Chain 5 (ITIH5) Is a Natural Stabilizer of Hyaluronan That Modulates Biological Processes in the Skin by Huth S. (4135366)

“…Performing the in vitro KeratinoSens skin sensitization assay, we detected that ITIH5 decreases the sensitizing potential of moderate and strong contact sensitizers. …”