Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

Subjects:

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

Subjects:

Retinoic acid decreases intracellular K⁺ in pectoral fin buds via transcriptional activation of the calcineurin inhibitor <i>rcan2</i>. by Xiaowen Jiang (8291814)

A. We randomly selected 20 mutually exclusive groups of protein complexes that contained exactly five subunits; we mapped the corresponding gene pairs to SINaTRA scores, and plotte... by Alexandra Jacunski (5665486)

“…A SINaTRA cutoff of 0.95 has approximately half of its pairs associated with the same complex; however, a decrease in the cutoff shifts this balance. …”

Segmentation of cerebral subcortical deep gray matter with FSL-FIRST and FreeSurfer pipelines. by Renxin Chu (5169857)

Two fully automated segmentation pipelines used to determine change in whole brain volume. by Renxin Chu (5169857)

“…PBVC was -0.9% (decreased) over the study period. SPM12 = statistical parametric mapping, v. 12; SIENA = structural image evaluation, using normalization, of atrophy, v. 5.0 (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0206939#sec007" target="_blank">Methods</a> section for details).…”

Whole brain volume change over 5 years using the SIENA pipeline. by Renxin Chu (5169857)

Ionic currents of aglycoform decreased more readily during repetitive depolarization pulses than glycoform. by M. K. Hall (352643)

Cerebral deep gray matter volume change over 5 years with the FSL-FIRST pipeline. by Renxin Chu (5169857)

Trial Sequential Analysis, parallel group trials, decreased appetite, nausea, vomiting, and abdominal pain. by Mathilde Holmskov (4112062)

“…Therefore, based on the assumed intervention effect of RRR of 10%, an alpha of 5%, and a beta of 20% we may still need more evidence on this adverse event.…”

Definitions of the features selected [50]. by Yu Zhang (12946)

Competition localization increases with growth rate or the distances between colonies, and decreases with the resource diffusion constant. by Jeremy M. Chacón (8259792)

Data_Sheet_1_Microclimatic Warming Leads to a Decrease in Species and Growth Form Diversity: Insights From a Tropical Alpine Grassland.PDF by Sisimac A. Duchicela (11503918)

“…We installed five monitoring blocks in 2012 at ca. 4,200 m asl with 20 OTCs and 50 control plots randomly distributed within each block. …”

Untargeted metabolomic analysis of delayed death-parasites indicates isoprenoid defect and decreased haemoglobin turnover. by Kit Kennedy (4915510)

DJ-1 gene deletion decreases mitochondrial respiratory chain function in dopaminergic neuronal cells. by Jun Young Heo (179572)

Gene ontology biological processes overrepresented among genes exhibiting decreased expression in human psoriasis. by William R. Swindell (175427)

“…<p>A total of 3540 transcripts were identified as significantly decreased in psoriatic plaques obtained from human patients relative to normal skin obtained from control subjects (FDR-adjusted P<0.05 and log₂-transformed fold-change less than -0.50). …”

B-RAF inhibitor PLX4720 decreased hERG currents in rhabdomyosarcoma RD cells. by Tatsiana Pakladok (311653)

Responses to asynchronous pulses of the control, LN, NSI and mix model, similar to Fig 8 but for a short synaptic time scale <i>τ</i>_<i>LN</i> = 25<i>ms</i>. by Mario Pannunzi (553941)

Raw data V-trial. by Torsten Schober (20485754)

“…Empirical models for the relationships between the investigated plant traits and PD/DVP were created using linear regression analysis preceded by a lack-of-fit test. An increase in PD led to a linear decrease in inflorescence yield per plant (<i>p</i> = 0.02), whereas a positive linear relationship was found for inflorescence yield (<i>p</i> = 0.0001) and CBD yield (<i>p</i> = 0.0002) per m². …”

Genetic progress for FFB (in percentage of hybrids performance at generation 0) in the La Mé population according to breeding scheme (RRS with 120 candidates, RRGS with 120 candida... by Billy Tchounke (16965084)