Systemic effects of angiogenesis inhibition alter pharmacokinetics and intratumoral delivery of <i>nab</i>-paclitaxel by Anne Steins (839229)

“…In this study, patient-derived xenograft mouse models of esophageal adenocarcinoma were used to identify the effects of DC101, a murine vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor, on the pharmacokinetics and the intratumoral uptake of <i>nab</i>-paclitaxel (NPTX). We showed that DC101 had large systemic effects resulting in decreased vasculature of intraperitoneally located organs. …”

Image_10_GPCR19 Regulates P2X7R-Mediated NLRP3 Inflammasomal Activation of Microglia by Amyloid β in a Mouse Model of Alzheimer’s Disease.tif by Jahirul Islam (11280516)

“…Furthermore, TDCA enhanced phagocytosis of Aβ and decreased the number of Aβ plaques in the brains of 5x Familial Alzheimer’s disease (5xFAD) mice. …”

Table_4_Global Transcriptomic Analysis of the Canine corpus luteum (CL) During the First Half of Diestrus and Changes Induced by in vivo Inhibition of Prostaglandin Synthase 2 (PTG... by Miguel Tavares Pereira (7857989)

“…Little effect was observed on days 5 and 10. Day 20 had the highest number of DEGs (n = 1,741), related with increased immune response. …”

DataSheet_1_Neutralization of SARS-CoV-2 Variants by mRNA and Adenoviral Vector Vaccine-Elicited Antibodies.docx by Takuya Tada (12208922)

“…BNT162b2 and mRNA-1273-elicited antibodies showed modest neutralization resistance against Beta, Delta, Delta plus and Lambda variants whereas Ad26.COV2.S-elicited antibodies from a significant fraction of vaccinated individuals had less neutralizing titer (IC₅₀ <50). …”

EspO promotes neutrophile transmigration. by Cedric N. Berger (4544008)

Model test results. by Zijie Li (776536)

Supplementary Material for: Intrauterine growth restriction disrupts the postnatal critical period of synaptic plasticity in the mouse dorsal hippocampus in a model of hypertensive... by St.Pierre M. (11862722)

“…ImageJ/Fiji and IMARIS were used for image processing and SPSS v24 for statistical analysis. Results: Although PV+ interneuron (IN) numbers and IR intensity were unchanged, development of GAD65/67+ synaptic boutons was accelerated at P18 IUGR mice, and inversely correlated with decreased expression of PSA-NCAM in the CA of P18 IUGR mice at P18. …”

Cortical UP DOWN state synchrony drives propofol phase amplitude coupling in slow waves by Austin Soplata (12089999)

“…In contrast, applying indirect propofol effects via decreasing acetylcholine (ACh) cortical tone enabled cortical SWO generation by decreasing pyramidal K(Na)-current conductance. …”

Supplementary file 1_Effects of nitrogen addition on SOC in alpine grasslands of the Qinghai-Tibetan Plateau and adjacent mountain regions: a meta-analysis.docx by Yanhui Ye (22775894)

“…Conversely, soil respiration decreased by 5.1%, whereas the microbial respiration rate increased by 21.9%. …”

The numerical verification of (22), the variance of in Theorem 1. by Rubao Ma (660015)

“…As a reference, the contamination-free version (50) is also posted together (see dashed curves).…”

Table_1_Global, Regional, and National Death, and Disability-Adjusted Life-Years (DALYs) for Cardiovascular Disease in 2017 and Trends and Risk Analysis From 1990 to 2017 Using the... by Zhiyong Li (47765)

“…The ASDR of CVD in high SDI regions decreased more than 50% from 1990 to 2017. Tobacco use, diets low in whole grains, diets high in sodium, and high systolic blood pressure were the important risk factors related to CVD mortality.…”

Table 2_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.docx by Leqing Zhou (20981021)

“…There were no significant differences between the KSS and RNU groups in terms of 5-year OS, 5-year CSS, 5-year RFS, 5-year IVRFS, 5-year MFS, and hazard ratios (HRs) for OS and CSS based on univariate or multivariable Cox regression analysis. …”

Image 3_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.tif by Leqing Zhou (20981021)

“…There were no significant differences between the KSS and RNU groups in terms of 5-year OS, 5-year CSS, 5-year RFS, 5-year IVRFS, 5-year MFS, and hazard ratios (HRs) for OS and CSS based on univariate or multivariable Cox regression analysis. …”

Table 1_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.docx by Leqing Zhou (20981021)

“…There were no significant differences between the KSS and RNU groups in terms of 5-year OS, 5-year CSS, 5-year RFS, 5-year IVRFS, 5-year MFS, and hazard ratios (HRs) for OS and CSS based on univariate or multivariable Cox regression analysis. …”

Image 1_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.tif by Leqing Zhou (20981021)

“…There were no significant differences between the KSS and RNU groups in terms of 5-year OS, 5-year CSS, 5-year RFS, 5-year IVRFS, 5-year MFS, and hazard ratios (HRs) for OS and CSS based on univariate or multivariable Cox regression analysis. …”

Table 1_Aurora: a mobile-based cognitive behavioral therapy intervention for anxiety and depression in Mexico.docx by Alejandro López-Tello (22409383)

“…</p>Results<p>Anxiety scores decreased from 13.2 (SD 5.6) to 10.6 (SD 5.1) (t(37) = 3.81, p = 0.001; d = 0.49), and depression scores from 11.1 (SD 5.2) to 8.4 (SD 4.9) (t(37) = 4.75, p < 0.001; d = 0.54). …”

Exceptionally high prevalence of iron deficiency anaemia in children residing in rural areas in Pakistan by Aleena Baig (18108142)

“…The prevalence of anaemia was 73.5% in males and 75.1% in females. With regard to age, the highest prevalence (86.5%, 64/74) was observed in children aged ≤5 years (mean Hb 9.7 g/dL; standard deviation=1.7; range, 6.3-13.6), followed by 75.8% (266/351) in those aged 6-10 years and 66.1% (111/168) in those aged 11-15 years.…”

Table_1_Optimal combination of arsenic trioxide and copper ions to prevent autoimmunity in a murine HOCl-induced model of systemic sclerosis.pdf by Charlotte Chêne (11221620)

“…Our results provide evidence that co-treatment with ATO 2.5 μg/g + CuCl₂ 0.5 μg/g decreases the number of B cells and the activation of CD4⁺ T lymphocytes. …”

Image 2_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.tif by Leqing Zhou (20981021)

“…There were no significant differences between the KSS and RNU groups in terms of 5-year OS, 5-year CSS, 5-year RFS, 5-year IVRFS, 5-year MFS, and hazard ratios (HRs) for OS and CSS based on univariate or multivariable Cox regression analysis. …”

From short transient to non-amplifying with weakened inhibition. by Georgia Christodoulou (809735)

“…<b>C</b>, Maximum response norm for all orthogonal conditions, in decreasing order. Grey dotted line corresponds to a response norm that is 50% larger than the norm of the initial condition. …”