Data_Sheet_1_Efavirenz restored NMDA receptor dysfunction and inhibited epileptic seizures in GluN2A/Grin2a mutant mice.PDF by Teng Zhao (1486717)

“…Mice with GluN2A/GRIN2A-V685G mutation exhibited shorter latency to seizure, increased frequency of seizure-like events, decreased peak current and current area of NMDAR excitatory postsynaptic current, and decreased event frequency of micro-inhibitory postsynaptic current, compared to WT mice. …”

Transmission of tuberculosis in rural Henan, China: a prospective population-based genomic spatial epidemiological study by Zhuo Quan (17658835)

“…The clustering risk decreased rapidly with increasing distances between patient residences, but 77.6% of clustered patient pairs lived ≥5.0 km apart. …”

The impact of chronic kidney disease on developed countries from a health economics perspective: A systematic scoping review by Sarah Elshahat (8587107)

“…Mean EuroQol-5D index scores ranged from 0.80 to 0.86 for CKD stages 1–3, and decreased to 0.73–0.79 for CKD stages 4–5. …”

PRISMA flow diagram. by Nicole E. Smolinski (18840931)

“…</p><p>Results</p><p>24 studies were included. Antibiotics decreased the risk of acute mastoiditis [incidence 0.02%, RR 0.48, 95% CI 0.40–0.59; NNT 5,368]. …”

Characteristics of included studies. by Nicole E. Smolinski (18840931)

“…</p><p>Results</p><p>24 studies were included. Antibiotics decreased the risk of acute mastoiditis [incidence 0.02%, RR 0.48, 95% CI 0.40–0.59; NNT 5,368]. …”

Funnel plot for studies evaluating mastoiditis. by Nicole E. Smolinski (18840931)

“…</p><p>Results</p><p>24 studies were included. Antibiotics decreased the risk of acute mastoiditis [incidence 0.02%, RR 0.48, 95% CI 0.40–0.59; NNT 5,368]. …”

Kaplan-meier survival analysis of 360 EOC patients. by Mirielle C. Ma (18990490)

Predictions for the annual age-standardized disability-adjusted life years (ASDR) attributable to hepatitis B virus (HBV) infection in China until 2035 on the basis of the Bayesian... by Xinyue Qi (9637055)

Effect of ibuprofen (IBU) on NF by Katarina Grossmannova (7543517)

“…<p><b>κ</b><b>B protein level and its transcriptional activity.</b> (A) Detection of NFκB precursor p105, NFκB subunits p50 and p60 and other NFκB-related proteins in HCT116, RKO, FaDu and UM-22A cells incubated in hypoxia under IBU treatment (0.5 mM and 1 mM) by Western blot demonstrated decreased NFκB levels and impaired transcriptional activity of NFκB. …”

A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia by Nagore I. Marín-Ramos (1600555)

“…In this work we report a potent ICMT inhibitor, compound <b>3</b> [UCM-1336, IC₅₀ = 2 μM], which is selective against the other enzymes involved in the post-translational modifications of Ras. …”

A novel one-pot green synthesis of selenium nanoparticles and evaluation of its toxicity in zebrafish embryos by Kalimuthu Kalishwaralal (1398034)

“…<p>Over the last 50 years, compelling evidence has accumulated on the beneficial role of selenium in human health. …”

A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia by Nagore I. Marín-Ramos (1600555)

“…In this work we report a potent ICMT inhibitor, compound <b>3</b> [UCM-1336, IC₅₀ = 2 μM], which is selective against the other enzymes involved in the post-translational modifications of Ras. …”

A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia by Nagore I. Marín-Ramos (1600555)

“…In this work we report a potent ICMT inhibitor, compound <b>3</b> [UCM-1336, IC₅₀ = 2 μM], which is selective against the other enzymes involved in the post-translational modifications of Ras. …”

4T1-luc2-1A4 tumor metastases in syngeneic Balb/c mice. by Jae-Beom Kim (25395)

“…<p>(A) Metastases of 4T1-luc2-1A4 tumors in Balb/c mice. 5.0×10⁴ cells were orthotopically implanted into mammary fat pads of the mice (n = 16)<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0009364#pone.0009364-Jenkins1" target="_blank">[1]</a>. …”

Comparison of the CFU burdens in the lung and spleen after a lethal pulmonary infection after 60 hours. by William J. Wilson (271312)

“…CZ was the only treatment able to significantly reduce CFU burden in the lung and spleen (A-B). However, there is a noticeable decrease in spleen bacterial burden in both groups treated with TA. …”

Fig 5 - by Deborah Ribeiro Frazão (9188152)

Electrical Modulation of Random Lasing Emission from ZnO Nanopowder and Liquid Crystal Hybrid Polymer Film by Naoto Hara (18089959)

“…By analyzing pumping power dependence of the photoemission intensity with a rate equation model of a two-level gain system in a cavity, we found that the enhancement of lasing emission is caused by the decrease in random cavity loss due to the electrical application. …”

Resolving a Natural Product Cold Case: Elucidation of Fusapyrone Structure and Absolute Configuration and Demonstration of Their Fungal Biofilm Disrupting Properties by Yun-Seo Kil (831249)

“…Among the main challenges posed by fusapyrones is the incorporation of several single and groups of stereocenters separated by atoms with freely rotating bonds, which have proven unyielding to spectroscopic analyses. In this study, we obtained a series of new (<b>2</b>–<b>5</b> and <b>7</b>–<b>9</b>) and previously reported fusapyrones (<b>1</b> and <b>6</b>), which were subjected to a combination of spectroscopic, chemical, and computational techniques enabling us to offer proposals for their full structures, as well as provide a pathway to reinterpreting the absolute configurations of other published fusapyrone metabolites. …”

Resolving a Natural Product Cold Case: Elucidation of Fusapyrone Structure and Absolute Configuration and Demonstration of Their Fungal Biofilm Disrupting Properties by Yun-Seo Kil (831249)

“…Among the main challenges posed by fusapyrones is the incorporation of several single and groups of stereocenters separated by atoms with freely rotating bonds, which have proven unyielding to spectroscopic analyses. In this study, we obtained a series of new (<b>2</b>–<b>5</b> and <b>7</b>–<b>9</b>) and previously reported fusapyrones (<b>1</b> and <b>6</b>), which were subjected to a combination of spectroscopic, chemical, and computational techniques enabling us to offer proposals for their full structures, as well as provide a pathway to reinterpreting the absolute configurations of other published fusapyrone metabolites. …”

NUC-7738 induces apoptosis in AML cell lines. by Akbar Muhammed Shahid (14266332)