Effect of 4‑HNE Modification on ZU5-ANK Domain and the Formation of Their Complex with β‑Spectrin: A Molecular Dynamics Simulation Study by Antistio Alviz-Amador (8174016)

“…However, effects at the atomic level of this carbonylation on structure and function of modified protein are not yet fully understood. We present a study based on molecular dynamics simulations of nine 4-HNE modified residues of the ZU5-ANK ankyrin domain with β-spectrin and their binding energy profiles. …”

ZFYVE1 negatively regulates MDA5- but not RIG-I-mediated innate antiviral response by Xuan Zhong (514234)

“…Mechanistically, ZFYVE1 interacted with MDA5 but not RIG-I. ZFYVE1 bound to viral RNA and decreased the ligand binding and oligomerization of MDA5. …”

Effect of 4‑HNE Modification on ZU5-ANK Domain and the Formation of Their Complex with β‑Spectrin: A Molecular Dynamics Simulation Study by Antistio Alviz-Amador (8174016)

“…However, effects at the atomic level of this carbonylation on structure and function of modified protein are not yet fully understood. We present a study based on molecular dynamics simulations of nine 4-HNE modified residues of the ZU5-ANK ankyrin domain with β-spectrin and their binding energy profiles. …”

Effect of 4‑HNE Modification on ZU5-ANK Domain and the Formation of Their Complex with β‑Spectrin: A Molecular Dynamics Simulation Study by Antistio Alviz-Amador (8174016)

“…However, effects at the atomic level of this carbonylation on structure and function of modified protein are not yet fully understood. We present a study based on molecular dynamics simulations of nine 4-HNE modified residues of the ZU5-ANK ankyrin domain with β-spectrin and their binding energy profiles. …”

Effect of DE of <i>S. malaccense</i> and <i>S. samarangense</i> leaves on A) ATP, B) p-mTOR, C) beclin-1, and D) p-AMPK levels. by Fatma A. Moharram (9276104)

Effect of different nitrate levels on chlorophyll fluorescence parameters of spinach. by Kangning Han (12001445)

Effect of DE of <i>S. malaccense</i> and <i>S. samarangense</i> on A) GSH, B) SOD, C) TNF-α, D) IL-1β, E) p-NF-κB, and F) Caspase-3 levels. by Fatma A. Moharram (9276104)

Mitogen-Activated Protein Kinase Kinase 5 Regulates Proliferation and Biosynthetic Processes in Procyclic Forms of <i>Trypanosoma brucei</i> by Fernanda G. Kugeratski (4575853)

“…The silencing of MKK5 significantly decreased the proliferation of procyclic forms of <i>T. brucei</i>. …”

Mitogen-Activated Protein Kinase Kinase 5 Regulates Proliferation and Biosynthetic Processes in Procyclic Forms of <i>Trypanosoma brucei</i> by Fernanda G. Kugeratski (4575853)

“…The silencing of MKK5 significantly decreased the proliferation of procyclic forms of <i>T. brucei</i>. …”

image_5_Impact of Aging on the Frequency, Phenotype, and Function of CD161-Expressing T Cells.PDF by Kornelis S. M. van der Geest (478975)

“…In addition, aging was associated with a decrease of nonclassic T helper 1 cells, as indicated by decreased percentages of CD161-expressing cells within the IFN-γ⁺ CD4⁺ T cell compartment of old subjects. …”

Synthesis and Mechanisms of Black Polyimide Films with High Mechanical and Dielectric Strength: Effects of Multicomponent Polymerization and Doping by Changqing He (19516063)

“…With this method, the addition of black additive decreases from over 5 to 0.5 wt %. PMDA and BPDA regulate the rigidity of the polymer chains and the intermolecular interactions, thereby improving the mechanical and dielectric strength. …”

Preventive effect on tracheal stenosis by the single and daily injection of MEK inhibitor. by Akari Kimura (11502013)

Influence of Precursor Solution Composition on the Electrical Properties of Solution-Processed Indium Tin Oxide Thin Films by Jingwei Zhang (288128)

“…The results reveal that incorporating nitrate anion-based precursors and Sn (II)-based precursors in the solutions leads to the ITO film with a low resistivity of 3.5 × 10^–3 Ω cm. This performance is attributed to the abundant formation of M-O-M bonds and the appropriate concentration of oxygen vacancies in the polycrystalline ITO films. …”

Design, Synthesis, and Cellular Characterization of a New Class of IPMK Kinase Inhibitors by Yubai Zhou (3931427)

“…The kinase activity of human inositol phosphate multikinase (IPMK) is required for the synthesis of higher-order inositol phosphate signaling molecules, regulation of gene expression, and control of the cell cycle. Here, we report a novel series of highly potent IPMK inhibitors. …”

Influence of Precursor Solution Composition on the Electrical Properties of Solution-Processed Indium Tin Oxide Thin Films by Jingwei Zhang (288128)

“…The results reveal that incorporating nitrate anion-based precursors and Sn (II)-based precursors in the solutions leads to the ITO film with a low resistivity of 3.5 × 10^–3 Ω cm. This performance is attributed to the abundant formation of M-O-M bonds and the appropriate concentration of oxygen vacancies in the polycrystalline ITO films. …”

Synthesis and Mechanisms of Black Polyimide Films with High Mechanical and Dielectric Strength: Effects of Multicomponent Polymerization and Doping by Changqing He (19516063)

“…With this method, the addition of black additive decreases from over 5 to 0.5 wt %. PMDA and BPDA regulate the rigidity of the polymer chains and the intermolecular interactions, thereby improving the mechanical and dielectric strength. …”

Visible-Light Paternò–Büchi Reaction for Lipidomic Profiling at Detailed Structure Levels by Hengxue Shi (14775004)

“…Around 90% conversion can be achieved at high concentrations (>0.5 mM) for different classes of lipids but drops as the lipid concentration decreases. …”

Synthesis and Mechanisms of Black Polyimide Films with High Mechanical and Dielectric Strength: Effects of Multicomponent Polymerization and Doping by Changqing He (19516063)

“…With this method, the addition of black additive decreases from over 5 to 0.5 wt %. PMDA and BPDA regulate the rigidity of the polymer chains and the intermolecular interactions, thereby improving the mechanical and dielectric strength. …”

Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms by Farman M. Abbasi (22318766)

“…Current treatments, such as teriparatide, boost bone formation but also elevate resorption, limiting their long-term effectiveness. We discovered 3-butyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-<i>d</i>]pyrimidin-4(3<i>H</i>)-one <b>(5cc)</b>, an orally active phosphodiesterase-1 (PDE1) inhibitor aimed at restoring this balance. …”

Low-Temperature Methane Combustion Using Ozone over Coβ Catalyst by Shunsaku Yasumura (8519667)

“…During a long-term catalytic test for 160 h without external heating, the CH₄ conversion gradually decreases from 80 to 40%, but the conversion fully recovers after dehydration at 500 °C (0.5 h). …”