Kinin B₁R inhibition or genetic deletion decreased the level of inflammatory cell infiltration and the demyelination area in experimental EAE. by Rafael C. Dutra (205755)

A genome-wide association study implicates that the <i>TTC39C</i> gene is associated with diabetic maculopathy with decreased visual acuity by Weihua Meng (2954112)

Overexpression of miR-520c-3p in DLBCL diminished colony formation in clonogenic assay and decreased tumor growth in xenograft model. by Krystyna Mazan-Mamczarz (37065)

Emerging Disinfection Byproduct 2,6-Dichlorobenzoquinone-Induced Cardiovascular Developmental Toxicity of Embryonic Zebrafish and Larvae: Imaging and Transcriptome Analysis by Xue Yang (144876)

“…Fluorescent images of transgenic zebrafish strains with fluorescently labeled heart and blood vessels show that DCBQ exposure resulted in deformed atrium–ventricle looping, degenerated abdomen and trunk vessels, pericardial edema, and decreased blood flow. Furthermore, the expression of the marker gene <i>myl7</i> (essential for the differentiation and motility of cardiomyocytes) was inhibited in a dose-dependent manner by DCBQ exposure. …”

Beverage Containing Dispersible Yeast β-Glucan Decreases Cold/Flu Symptomatic Days After Intense Exercise: A Randomized Controlled Trial by Eunice Mah (5918042)

“…<p>In this double-blind, randomized, placebo-controlled parallel study, we examined the effect of dairy-based beverages (250 mL/day) containing 250 mg of dispersible baker’s yeast β-glucan (Wellmune) compared to a macronutrient- and calorie-matched control on upper respiratory tract infection (URTI) in marathon runners. …”

The potency of the blockage of FXIa varies over the subsets of fibrin concentration. by Jason Chen (15937)

Effect of inhibitory antibodies and human serum on NA enzymatic function ELLA and NA Star. by Harrison Powell (9040128)

Local sensitivity analysis of total thrombin, free, and bound thrombin in the clot. by Jason Chen (15937)

SPL treatment decreases diabetes-induced decrement in protein expression of cldn-5 in glomeruli (GL) and cldn-2 and occldn in proximal tubules (PT). by Eduardo Molina-Jijón (4020464)

“…<p>SPL prevents diabetes-induced decrease of cldn-5 protein expression (A and B) in GL, and mRNA (F) and protein expression of cldn-2 (A and C), and protein expression of occldn (A and D) in PT (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0177362#pone.0177362.s002" target="_blank">S2 Fig</a>). …”

Total, free, and bound thrombin of 10,000 simulations of blood clotting over collagen/ TF under venous flow rate. by Jason Chen (15937)

Plasma protein levels and thrombin binding sites distribution of the subsets of top and bottom 2% of fibrin concentration of 10,000 simulations. by Jason Chen (15937)

Fibrin concentration of 10,000 simulations compared to experimental data of blood clotting over collagen/ TF under venous flow rate. by Jason Chen (15937)

Simultaneous ablation of Syt1 and Syt7 decreases the RRP size at inhibitory synapses: Rescue by WT but not mutant Syt1 or Syt7. by Taulant Bacaj (803415)

“…Recordings were performed in the presence of 1 μM tetrodotoxin, 20 μM CNQX, and 50 μM AP5 to isolate inhibitory currents. <b>B.</b> Simultaneous ablation of Syt1 and Syt7 decreases the RRP size of inhibitory synapses in a manner that is rescued by WT Syt7 (Syt1^WT) but not Syt7 with mutations in the top C2 domain sequences containing the Syt7 Ca²⁺ binding sites (Syt7^C2A*^B*). …”

Silencing of <i>Bma-aldolase-2</i> decreases <i>Wolbachia</i> load in adult female worms and induces apoptosis in developing embryos. by Denis Voronin (257924)

Decreased total iron binding capacity upon intensive care unit admission predicts red blood cell transfusion in critically ill patients by Taro Imaeda (6256550)

“…<div><p>Introduction</p><p>Red blood cell (RBC) transfusion is associated with poor clinical outcome in critically ill patients. We investigated the predictive value of biomarkers on intensive care units (ICU) admission for RBC transfusion within 28 days.…”

Reduced ezrin or p130Cas expression in ES2 cells resulted in decreased cell branching capacity on Matrigel and reduced invasion ability. by Vered Horwitz (3117960)

“…ES2 cells with reduced ezrin expression (ES2-T2) showed 50% decrease in invasion ability compared the cells transfected with no plasmid (ES2-C1) and non-transfected cells (ES2-C2) (*, p<0.01). …”

Proportions of activated (CD38+HLA-DR+) and cycling (Ki67+) CD4+ and CD8+ T cells decreased following initiation of ART. by Nicholas T. Funderburg (379171)

“…<div><p>Among both A) CD4+ and B) CD8+ T cell populations, initiation of raltegravir plus emtricitabine/tenofovir resulted in a significant decrease from baseline in the proportion of activated cells by 2 days and 7 days (p= 0.05 and 0.015, respectively). …”

Table_5_Effect of high-dose Spirulina supplementation on hospitalized adults with COVID-19: a randomized controlled trial.docx by Mohammad Reza Aghasadeghi (9524778)

“…This study aimed to evaluate the efficacy and safety of high-dose Spirulina platensis for SARS-CoV-2 infection.</p>Study Design<p>We conducted a randomized, controlled, open-label trial involving 189 patients with COVID-19 who were randomly assigned in a 1:1 ratio to an experimental group that received 15.2g of Spirulina supplement plus standard treatment (44 non-intensive care unit (non-ICU) and 47 ICU), or to a control group that received standard treatment alone (46 non-ICU and 52 ICU). …”

Data_Sheet_5.xlsx by Uwe Möginger (4987334)

The dental arch length at three timepoints: (A) at the patient’s birth, (B) at cheiloplasty, and (C) at palatoplasty. by Miki Kashiwagi (21439684)