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5681
Sema3a inhibits the differentiation of Raw264.7 cells to osteoclasts under 2Gy radiation by reducing inflammation
Published 2018“…Raw264.7 cells were divided into four groups: A, receiving no radiation; B, receiving no radiation + 50ngng/ml Sema3a; C, receiving 2Gy radiation; and D, receiving 2Gy radiation +50ngng/ml Sema3a. …”
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5682
The changes of EFR3A expression in the organ of Corti in the animals treated with kanamycin and furosemide by western blotting.
Published 2015“…<p>TUJ1 protein, with a molecular weight of 50 KD, was identified as an internal reference. …”
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5683
Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments
Published 2018“…The crystal structures of TyBm with inhibitor <b>3</b> (IC<sub>50</sub> value of 25.11 μM) and <b>16</b> (IC<sub>50</sub> value of 5.25 μM) were solved, confirming the binding poses hypothesized by in silico studies and revealing the main molecular determinants for the binding recognition of the inhibitors.…”
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5684
Table_5_The non-canonical inflammasome activators Caspase-4 and Caspase-5 are differentially regulated during immunosuppression-associated organ damage.docx
Published 2023“…We report that CASP4 and CASP5 are differentially regulated during acute-on-chronic liver failure and sepsis-associated immunosuppression, suggesting non-redundant functions in the inflammasome response to infection. …”
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5685
Investigate Pathogenic Mechanism of TXNDC5 in Rheumatoid Arthritis
Published 2013“…We previously detected increased TXNDC5 expression in synovial tissues and blood from RA patients and demonstrated that the gene encoding TXNDC5 increased RA risk. …”
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5686
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5687
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5688
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5689
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5690
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5691
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5692
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5693
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5694
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5695
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5696
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5697
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5698
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5699
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5700
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”