Data processing and analysis steps. by Alexandra V. Kulinkina (5335058)

“…We derived environmental variables from fine-resolution RS data (Landsat 8) and examined a variable distance radius (1–5 km) for aggregating these variables around point-prevalence locations in a non-parametric random forest modeling approach. …”

Bortezomib initiates endoplasmic reticulum stress, elicits autophagy and death in <i>Echinococcus granulosus</i> larval stage by María Celeste Nicolao (4373458)

“…No changes were detected in the transcriptional expression of chaperones in Bz-treated metacestodes, thus allowing ER stress to be evident and viability to highly decrease in comparison with protoscoleces. We also found that Bz treatment activated the autophagic process in both larval forms. …”

Sample Data from the Local HTS, Z'-factor Summary and Hit Summary. by Umesh K. Bageshwar (2271628)

Immunohistochemical staining showing the expression of phosphorylated p38 in the mouse renal tubulointerstitial area after UUO and administration of p38 MAPK inhibitor. by Jeonghwan Lee (286889)

“…<p>Scale bar = 50 μm (original magnification x300). (A) Sham-operated group. …”

Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity by Baoli Li (4450708)

“…More than 100 new compounds were synthesized, which target the overwhelming the defects of the CrtN inhibitor <b>1</b>. Analogues <b>23a</b> and <b>23b</b> demonstrated a significant activity against pigmented <i>S. aureus</i> Newman and 13 MRSA strains (IC₅₀ = 0.02–10.5 nM), along with lower hERG inhibition (IC₅₀ > 30 μM, ∼10-fold decrease in comparison with <b>1</b>). …”

LPS treatment leads to contractile responses only in the GSTCD deleted PCLS. by Bo Liu (127343)

<i>VT16839-Gal4</i> neurons trigger and are critical in consumption behavior. by Samantha K. Cheung (3897748)

“…<p><b>A)</b><i>VT16839-Gal4</i> drives expression of <i>UAS-mCD8</i>::<i>GFP</i> in the brain and VNC (scale bar = 100 μm) <b>B)</b> RNA interference knockdown of <i>Rdl</i> in <i>VT16839-Gal4</i> neurons increased consumption time of water, 1 mM denatonium, 500 mM sucrose and 20% PEG. …”

Image_5_Bioactive metabolites of Streptomyces misakiensis display broad-spectrum antimicrobial activity against multidrug-resistant bacteria and fungi.jpeg by Rewan Abdelaziz (12961639)

“…Background<p>Antimicrobial resistance is a serious threat to public health globally. It is a slower-moving pandemic than COVID-19, so we are fast running out of treatment options.…”

Phosphoproteome Profiling of SH-SY5y Neuroblastoma Cells Treated with Anesthetics: Sevoflurane and Isoflurane Affect the Phosphorylation of Proteins Involved in Cytoskeletal Regula... by Joomin Lee (3111468)

“…However, the molecular or biochemical processes within cells that regulate anesthetic-induced responses at the cellular level are largely unknown. Here, we report the phosphoproteome profile of SH-SY5y human neuroblastoma cells treated with sevoflurane, a clinically used anesthetic. …”

Oxygen-dependent regulation of tumor growth and metastasis in human breast cancer xenografts by Kristine Yttersian Sletta (4386352)

“…Treatment effects were determined by assessment of tumor growth, proliferation (Ki67-staining), angiogenesis (CD31-staining), metastasis (immunostaining), EMT markers (western blot), stromal components collagen type I, Itgb1 and FSP1 (immunostaining) and chemotherapeutic efficacy (5FU).</p><p>Results</p><p>HBOT significantly suppressed tumor growth in both the triple positive and negative tumors, and both MDA-MB-231 and BT-474 showed a decrease in proliferation after HBOT. …”

Predicted count of Leach’s Storm-Petrels (<i>H</i>. <i>leucorhous</i>) found during daily morning surveys at a seafood processing plant in Bay de Verde, Newfoundland and Labrador,... by Tori V. Burt (17261197)

Image_1_Loss of DEK Expression Induces Alzheimer’s Disease Phenotypes in Differentiated SH-SY5Y Cells.TIF by Allie N. Greene (9644915)

“…However, the functional role of DEK in neurons is unknown. Thus, we knocked down DEK in an in vitro neuronal model, differentiated SH-SY5Y cells, hypothesizing that DEK loss would result in cellular and molecular phenotypes consistent with AD. …”

An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens by Victoria A. Meliopoulos (166262)

“…Once expressed, αVβ6 moderates acute lung injury (ALI) through as yet undefined molecular mechanisms. …”

Data_Sheet_1_Platelet Phenotype Analysis of COVID-19 Patients Reveals Progressive Changes in the Activation of Integrin αIIbβ3, F13A1, the SARS-CoV-2 Target EIF4A1 and Annexin A5.d... by Huriye Ercan (11679229)

“…In total we monitored 98 surviving and 12 non-surviving COVID-19 patients over 5 days of hospital stay and compared them to healthy controls (n = 12).…”

XBP1 signalling is essential for alleviating mutant protein aggregation in ER-stress related skeletal disease by Katarzyna A. Piróg (490536)

“…In order to dissect the role of XBP1 signalling in aggregation-related conditions we crossed a p.V194D <i>Matn3</i> knock-in mouse model of EDM5 with a mouse line carrying a cartilage specific deletion of XBP1 and analysed the resulting phenotype. …”

Data Sheet 1_miR-379-5p retards the proliferation and differentiation of goat skeletal muscle satellite cells by targeting LIN28B.zip by Wenyue Hou (10203722)

“…<p>MicroRNAs (miRNAs) are emerging as crucial regulators of skeletal muscle development and regeneration; however, the biological functions of many miRNAs remain to be elucidated. In this study, we focused on the function of miR-379-5p, a miRNA we previously identified as highly expressed in the longissimus dorsi muscle of goats. …”

Data_Sheet_5_Sestrin2-Mediated Autophagy Contributes to Drug Resistance via Endoplasmic Reticulum Stress in Human Osteosarcoma.ZIP by Zhen Tang (2977569)

Molecular Modeling-_Based Delivery System Enhances Everolimus-Induced Apoptosis in Caco‑2 Cells by Marwan Abdelmahmoud Abdelkarim Maki (6725999)

“…However, the meaningful efficacy of EV as a single agent for the treatment of colorectal cancer (CRC) has failed to be proven in multiple clinical trials. …”

Table_2_Let-7e-5p Regulates IGF2BP2, and Induces Muscle Atrophy.xlsx by Takuro Okamura (7849262)

“…Moreover, we examined serum let-7e-5p levels among male subjects with type 2 diabetes.…”

Table_1_Let-7e-5p Regulates IGF2BP2, and Induces Muscle Atrophy.xlsx by Takuro Okamura (7849262)

“…Moreover, we examined serum let-7e-5p levels among male subjects with type 2 diabetes.…”