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Topiramate monotherapy for weight reduction in patients with type 2 diabetes mellitus: A systematic review and meta-analysis
منشور في 2016"…Results: Of the 284 studies identified, 5 studies fulfilled the inclusion criteria. Topiramate decreased weight by a mean difference of 3.4 kg (95% CI, -3.79 to -3.04) compared to placebo. …"
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223
Urology Residents' Perspectives on the In-House On-Call Systems: A Study in an Accredited Academic Center
منشور في 2022"…Quality of life and education: We adopted a validated survey based on a 5-point Likert scale to assess the residents' perception of the transition to a 12-hour on-call system on their quality of life and education. …"
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224
Changes in air quality during the first-level response to the COVID-19 pandemic in Shanghai Municipality, China
منشور في 2020"…The results showed that air quality improved significantly During-FLR compared with Pre-FLR, with the concentrations of PM2.5, PM10, SO2, NO2, and CO all decreasing significantly. …"
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225
A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase
منشور في 2019"…Considering true positives, true negatives, false positives, and false negatives, three mutations (Y114E, R128G, and C145A) showed "loss of DNA repair activity," and were analyzed further using molecular dynamics simulations (MDS) using GROMACS for 50ns. MDS run showed that the C145A mutant demonstrated higher structural deviation, decreased compactness, and the binding patterns. …"
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226
Regional Difference in the Association between the Trajectory of Selenium Intake and Hypertension: A 20-Year Cohort Study.
منشور في 2021"…The effect of selenium on hypertension is inconclusive. We aimed to study the relationship between selenium intake and incident hypertension. …"
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227
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Clinical characteristics and outcome of children with acute cryptorchid testicular torsion: A single-center, retrospective case series study
منشور في 2024"…Results We found eight patients with unilateral acute cryptorchid TT with a prevalence of 8.9% (8/90) among all TT cases. …"
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229
Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes), Supplementation Alters Gut Microbiome and Corrects Dyslipidemia in Rats.
منشور في 2019"…Wistar rats were offered a chow maintenance diet (CMD; CON group) or the same CMD ration with cholesterol (1.5% w/w) and cholic acid (0.5% w/w) added to induce hypercholesterolemia (day 1 to day 24). …"
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230
Evaluation of the inhibition performance of piperazine-based polyurea towards mild steel corrosion: The role of keto-enol tautomerization
منشور في 2022"…The presence of PUCorr at 100 ppm decreases the corrosion current density from 30.3 to 3.05 μA/cm2 in 0.5 M NaCl at room temperature, exhibiting a remarkable inhibition efficiency of 94.5%. …"
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231
Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria
منشور في 2024"…We observed that the disease-associated K72I genetic variant had no apparent effects on the spectroscopic and catalytic properties of the full-length enzyme. …"
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232
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Privacy-preserving federated learning cyber-threat detection for intelligent transport systems with blockchain-based security
منشور في 2022"…Furthermore, we conducted an experimental study to measure the effectiveness of the proposed prototype. …"
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234
Salvia fruticosa Induces Vasorelaxation in Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway
منشور في 2017"…Prior exposure to PI3K inhibitors, wortmannin (0.1 µM) or LY294002 (10 µM), decreased cGMP accumulation and attenuated the SF-induced vasorelaxation by approximately 50% (Rmax). …"
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High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i...
منشور في 2023"…These key performance indicators were slightly decreased when fingerstick whole-blood samples were used: sensitivity [85.7 %(63.7–97)], specificity [90.0 %,(81.5–96)], good agreement (Cohen's Kappa = 0.7) and very strong correlation (r = 0.9, p < 0.0001) with cobas® e 601. …"
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238
High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i...
منشور في 2023"…These key performance indicators were slightly decreased when fingerstick whole-blood samples were used: sensitivity [85.7 %(63.7–97)], specificity [90.0 %,(81.5–96)], good agreement (Cohen's Kappa = 0.7) and very strong correlation (r = 0.9, p < 0.0001) with cobas® e 601. …"
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239
Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal...
منشور في 2020"…Global life expectancy at birth increased from 67·2 years (95% UI 66·8–67·6) in 2000 to 73·5 years (72·8–74·3) in 2019. The total number of deaths increased from 50·7 million (49·5–51·9) in 2000 to 56·5 million (53·7–59·2) in 2019. …"
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240
Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal...
منشور في 2020"…Global life expectancy at birth increased from 67·2 years (95% UI 66·8–67·6) in 2000 to 73·5 years (72·8–74·3) in 2019. The total number of deaths increased from 50·7 million (49·5–51·9) in 2000 to 56·5 million (53·7–59·2) in 2019. …"
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