Switch to aflibercept in the treatment of neovascular age-related macular degeneration: 30-month results by Elif Ertan (10357215)

“…Before the transition, the patients received a mean of 16.8 ± 8.8 ranibizumab injections (range 6-38).After the transition to intravitreal aflibercept treatment, the mean number of aflibercept injections was 9.09 ± 3.94. …”

E protein residues critical for neutralization by bnAbs. by Jay Lubow (772012)

“…<p>(Left panel) Bar graphs show the mean IC50 fold change against DENV2 16681 reporter virus particles encoding E protein variants relative to wild type (WT) DENV2 for antibodies <b>(A)</b> F09.S05, <b>(B)</b> F05.S03, <b>(C)</b> J9, <b>(D)</b> F25.S02, and <b>(E)</b> EDE1-C10. …”

Supplementary Material for: Peripheral Eosinophil Count Associated with Disease Activity and Clinical Outcomes in Hospitalized Patients with Lupus Nephritis by Liu R. (4120498)

“…The primary outcome measure was a composite of doubling of serum creatinine and end-stage kidney disease after a median follow-up of 51 months. …”

Engraftment of hE in NOD<i>^{scid/β2m−/−}</i>. by Iñigo Angulo-Barturen (47469)

“…Data are the mean percentage±SE of hE (TER-119⁻ or human glycophorin-A⁺ mouse) erythrocytes pooled from 142 mice. …”

Table_1_Favorable Effects of Tacrolimus Monotherapy on Myasthenia Gravis Patients.DOCX by Zhirong Fan (9566711)

“…QMG scores significantly decreased at 6 and 12 months, with mean differences and 95% CIs of −4.67(−6.88, −2.45) and −5.77 (−7.55, −4.00), respectively. …”

Fig 2 - by Bettina C. Schwab (9515382)

“…Spike-density functions were z-scored relative to mean rate prior to go-cue presentation and displayed on a color scale. …”

DMN-separation study with agarose gel and schematic illustration of DMN-separation mechanism. by Miroo Kim (787779)

“…<p>(A) DMN-separation efficiency according to side junction depth. …”

Power of locus detection in sibling pairs assuming directionally concordant maternal and offspring genetic effects (red lines: <i>d</i>^<i>2</i> = 0.1%; <i>b</i><sup><i>2... by Liang-Dar Hwang (538238)

“…For all calculations we assume an autosomal locus, shared residual variance <i>φ</i>² = 0.2, a type 1 error rate α = 5x10^-8, and where relevant, a decreasing allele frequency of p = 0.1. …”

Administration of R037 inhibits the secretion of inflammatory cytokines. by Kazushiro Takata (339569)

“…Data are shown as mean + SEM from a representative of three independent experiments for 6 mice in the R037-treated and 8 in the control groups. …”

Monte Carlo simulation study results examining model robustness. by Christopher M. Gast (583187)

“…<p>Median relative bias and estimated coverage of asymptotic 95% confidence intervals for estimated total annual abundance for simulated small game data from simulations designed to address robustness. “Increasing S” (“Decreasing S”) scenario corresponds to a population with natural survival probability gradually increasing (decreasing) over the study period. …”

Data_Sheet_1_Transcriptomic and Proteomic Profiling Reveal the Key Role of AcMYB16 in the Response of Pseudomonas syringae pv. actinidiae in Kiwifruit.doc by Xiaojie Wang (166442)

“…Plant hormones may induce various secondary metabolites to resist pathogens via modulation of hormone-responsive transcription factors (TFs), as reported in past studies. In this study, we showed that JA accumulated in the susceptible cultivar Actinidia chinensis ‘Hongyang’ but decreased in the resistant cultivar of A. chinensis var. deliciosa ‘Jinkui’ in response to Psa. …”

Table_2_Transcriptomic and Proteomic Profiling Reveal the Key Role of AcMYB16 in the Response of Pseudomonas syringae pv. actinidiae in Kiwifruit.XLS by Xiaojie Wang (166442)

“…Plant hormones may induce various secondary metabolites to resist pathogens via modulation of hormone-responsive transcription factors (TFs), as reported in past studies. In this study, we showed that JA accumulated in the susceptible cultivar Actinidia chinensis ‘Hongyang’ but decreased in the resistant cultivar of A. chinensis var. deliciosa ‘Jinkui’ in response to Psa. …”

Data Sheet 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.docx by Maria Jordan (10265489)

“…</p>Methods<p>In silico modeling of dysregulated pathways in IPF and screening for putative interfering small molecules identified carvedilol as a promising anti-fibrotic agent. We validated drug-mediated effects on key features of fibroblast activation in functional assays and gene expression analyses in human embryonic lung fibroblasts (MRC-5). …”

Table 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.xlsx by Maria Jordan (10265489)

“…</p>Methods<p>In silico modeling of dysregulated pathways in IPF and screening for putative interfering small molecules identified carvedilol as a promising anti-fibrotic agent. We validated drug-mediated effects on key features of fibroblast activation in functional assays and gene expression analyses in human embryonic lung fibroblasts (MRC-5). …”

Table_1_Temperature-Dependent Lipid Accumulation in the Polar Marine Microalga Chlamydomonas malina RCC2488.docx by Daniela Morales-Sánchez (9911739)

“…Previously, when the polar marine microalga Chlamydomonas malina RCC2488 was cultivated under both nitrogen replete and depleted conditions at 8°C, it accumulated lipids and carbohydrates (up to 32 and 49%, respectively), while protein synthesis decreased (up to 15%). We hypothesized that the cultivation temperature had a more significant impact on lipid accumulation than the nitrogen availability in C. malina. …”

Image_4_Photosynthetic response of Chlamydomonas reinhardtii and Chlamydomonas sp. 1710 to zinc toxicity.TIF by Di Zhan (14842687)

“…The results demonstrated that Chlamydomonas sp. 1710 was much more tolerant to Zn than C. reinhardtii, with the half-maximal inhibitory concentration (IC50) values of 225.4 mg/L and 23.4  mg/L, respectively. The μ and Chl-a content of C. reinhardtii decreased in the presence of 15  mg/L Zn, whereas those of Chlamydomonas sp. 1710 were unaffected by as high as 100  mg/L Zn. …”

Inventory of ferns and lycophytes within forest fragments of Araucaria in southern Brazil by Ivanete Teresinha Mallmann (5694908)

“…For the floristic inventory, a parcel of 1 ha (100x100m) was demarcated inside three fragments, which were classified by size: large (246 ha - H1LF), medium (57 ha - H2MF) and small (5.2 ha - H3SF). …”

Proteomic Analysis of Drug-Resistant Mycobacteria: Co-Evolution of Copper and INH Resistance by Yuling Chen (438010)

“…The mc²155-Cu strain has a 5-fold higher resistance to copper sulfate and a 2-fold higher resistance to isoniazid (INH) than its parental strain mc²155, respectively. …”

Data Sheet 1_The role of microRNAs and long non-coding RNAs in epigenetic regulation of T cells: implications for autoimmunity.pdf by Soumil Prasad (22679354)

“…The majority of studies identified consistent patterns of dysregulation, including increased expression of miR21, miR148a, and miR155, and decreased expression of miR146a, GAS5, and IL21AS1. …”

Table_4_Transcriptomic and Proteomic Profiling Reveal the Key Role of AcMYB16 in the Response of Pseudomonas syringae pv. actinidiae in Kiwifruit.XLS by Xiaojie Wang (166442)

“…Plant hormones may induce various secondary metabolites to resist pathogens via modulation of hormone-responsive transcription factors (TFs), as reported in past studies. In this study, we showed that JA accumulated in the susceptible cultivar Actinidia chinensis ‘Hongyang’ but decreased in the resistant cultivar of A. chinensis var. deliciosa ‘Jinkui’ in response to Psa. …”