<i>In vitro</i> and <i>in vivo</i> antitumor activity of PEITC and Trisenox in imatinib resistant cells. by Jérome Kluza (5649763)

“…<p>(A) DA1-3b and DA1-3b/M2 cells were treated with 1, 3, 5, 10, 15 and 20 µM of the pro-oxidant phenethyl isothiocyanate (PEITC) for 18 h (left) or with 1, 5, 10 and 20 µM of arsenic trioxide (Trisenox) for 4 h then mitochondrial ROS production was assessed by flow cytometry using MitoSox. …”

Real-world cost-effectiveness of pan-genotypic Sofosbuvir-Velpatasvir combination versus genotype dependent directly acting anti-viral drugs for treatment of hepatitis C patients i... by Yashika Chugh (7325960)

“…The use of SOF+VEL only for cirrhotic patients (scenario II) increases QALYs by 0.28 (0.03 to 0.71) per person, and decreases the cost by ₹ 5,946 (₹ 1,198 to ₹ 14,174) per patient, when compared to scenario I. …”

Supplementary Material for: Adjudication of Transient Ischemic Attack and Stroke in the Multi-Ethnic Study of Atherosclerosis by Longstreth Jr. W.T. (4753620)

“…<b><i>Methods:</i></b> We detail the process used to adjudicate TIA and stroke in the Multi-Ethnic Study of Atherosclerosis (MESA), a large longitudinal cohort study. …”

Analysis of the relative contribution of each genomic feature to the CNV classifier. by Jayne Y. Hehir-Kwa (249792)

“…Removal of the LINE density from the classifier results in the largest decrease in accuracy (6%) whilst removing MGI knockout phenotypes results in a drop of 5% in accuracy. …”

Arene Binding Affinities in [CpRu(η⁶-arene)]⁺ Complexes: Models for the Adsorption of Arenes on Hydrodesulfurization Catalysts by Moon-Gun Choi (677628)

“…In general, alkyl-substituted arenes have a higher binding affinity than the parent arene, except for <i>tert</i>-butyl groups, which decrease the <i>Y</i> values. …”

RPL37, RPS15, and RPS20 bind to and regulate MdmX levels. by Lilyn Daftuar (433919)

“…<p>(a–c) Association of RPs and MdmX. H1299 cells were transfected with HA-MdmX (0.5 µg), Myc-RP (1.2 µg), or both. …”

Dissociative CO Photosubstitution in M(CO)₄(1,4-diazabutadiene) Complexes (M = W, Mo) by an Olefin Affording Novel <i>f</i><i>ac</i>-M(CO)₃(1,4-diazabutadiene... by Friedrich-Wilhelm Grevels (2671306)

“…Irradiation of <b>2</b> in low-temperature matrices, as monitored by means of IR spectroscopy in the ν(CO) region, was shown to yield <i>fac</i>-Mo(CO)₃(iprop-dab) (<b>5</b>, in Ar or CO-doped Ar), <i>fac</i>-Mo(CO)₃(¹³CO)(iprop-dab) (in ¹³CO-doped Ar), and <i>fac</i>-Mo(CO)₃(N₂)(iprop-dab) (<b>6</b>, in N₂), thereby establishing that a vacant axial coordination site is created by photolytic CO dissociation, with wavelength-dependent efficiency. …”

Open Regionalism: Lessons from Latin America for East Asia by Clark Reynolds (18888523)

Supplementary Material for: Trajectory of urine albumin-creatinine ratio in patients with acute heart failure (TACRAHF study) by Llàcer P. (17858765)

“…Estimates were reported as least squares mean (LSM) with their respective 95% CIs. Results: The median age of the study population was 87 years, 68.5% were women, and 69.8% had a left ventricular ejection fraction >50%. …”

Examining the Lateral Displacement of HL60 Cells Rolling on Asymmetric P-Selectin Patterns by Chia-Hua Lee (2239972)

“…On the basis of these experimental data, we constructed an empirical model that predicted the occurrence of the maximum lateral displacement at an edge angle of 7.5°. …”

Table_1_Sulprostone-Induced Gastric Dysrhythmia in the Ferret: Conventional and Advanced Analytical Approaches.XLSX by Zengbing Lu (5801171)

“…DFA revealed that sulprostone decreased the fluctuation function, indicative of a loss of the variability of GMA fluctuations around local trends. …”

Image_1_Sulprostone-Induced Gastric Dysrhythmia in the Ferret: Conventional and Advanced Analytical Approaches.pdf by Zengbing Lu (5801171)

“…DFA revealed that sulprostone decreased the fluctuation function, indicative of a loss of the variability of GMA fluctuations around local trends. …”

Data_Sheet_1_Concerted suppressive effects of carisbamate, an anti-epileptic alkyl-carbamate drug, on voltage-gated Na+ and hyperpolarization-activated cation currents.docx by Te-Yu Hung (15861305)

“…However, CRS strongly decreased the strength (i.e., Δarea) of the nonlinear window component of I_Na (I_Na(W)), which was activated by a short ascending ramp voltage (V_ramp); the subsequent addition of deltamethrin (DLT, 10 μM) counteracted the ability of CRS (100 μM, continuous exposure) to suppress I_Na(W). …”

Table1_Running vs. resistance exercise to counteract deconditioning induced by 90-day head-down bedrest.pdf by Adrien Robin (1640281)

“…Day–night variations in systolic BP were preserved during HDBR. Decrease in V˙O₂max positively correlated with decrease in thigh (r = 0.54 and p = 0.009) and calf (r = 0.52 and p = 0.012) circumferences. …”

Image_2_Schistosoma mansoni Infection Is Impacted by Malnutrition.TIF by Poliane Silva Maciel (10327754)

“…Mice fed with this diet showed: (i) significant reduction in body weight and serum albumin levels before infection, (ii) decreased levels of all biochemical parameters evaluated before perfusion, (iii) decreased numbers of schistosome eggs trapped in intestines and impaired parasite fecundity, (iv) a delay in the granuloma development with a smaller granuloma area, and (v) reduced levels of IL-4 and IFN-γ in the liver. …”

Image_1_Schistosoma mansoni Infection Is Impacted by Malnutrition.TIF by Poliane Silva Maciel (10327754)

“…Mice fed with this diet showed: (i) significant reduction in body weight and serum albumin levels before infection, (ii) decreased levels of all biochemical parameters evaluated before perfusion, (iii) decreased numbers of schistosome eggs trapped in intestines and impaired parasite fecundity, (iv) a delay in the granuloma development with a smaller granuloma area, and (v) reduced levels of IL-4 and IFN-γ in the liver. …”

Genome-Wide Screen of Three Herpesviruses for Protein Subcellular Localization and Alteration of PML Nuclear Bodies by Jayme Salsman (43452)

“…<div><p>Herpesviruses are large, ubiquitous DNA viruses with complex host interactions, yet many of the proteins encoded by these viruses have not been functionally characterized. As a first step in functional characterization, we determined the subcellular localization of 234 epitope-tagged proteins from herpes simplex virus, cytomegalovirus, and Epstein–Barr virus. …”

Properties of evolved FUS PLD. by Simon M. Lichtinger (11326846)

“…The data were computed at the same bead number density <i>N</i>/<i>V</i> = 7.0 nm⁻³ and temperature . In both cases, this temperature is below the critical point and the density corresponds to the protein-rich (liquid-like) phase, i.e. a point that lies above the binodal line on the phase diagram. …”

Additional file 1 of Characterisation of unessential genes required for survival under conditions of DNA stress by Hassan Ahmed Ezzat (8806121)

“…Additional file 1: Supplemental Figure S1 showing the comparison the adjusted relative quantity of RNA of strains carrying the V5 alleles. The figure shows the gradual decrease through graphical representation of the adjusted relative quantity between all the (A) Hip1-V5, (B) Swi1-V5, (C) Swi3-V5 and (D) Mrc1-V5 strains across the 24 hour timecourse after the addition of thiamine to the media.…”

DataSheet_1_PPARγ S273 Phosphorylation Modifies the Dynamics of Coregulator Proteins Recruitment.pdf by Marieli Mariano Gonçalves Dias (9698648)

“…Also, we observed that the CDK5 presence disturb the PPARγ-coregulator’s synergy, decreasing interaction with PGC1-α, TIF2, and NCoR, but increasing coupling of SMRT. …”