Supplementary Material for: Targeting cartilage miR-195/497 cluster for osteoarthritis treatment regulates the circadian clock by Shi S. (2945916)

“…Conclusion: Our findings identify a regulatory mechanism connecting chondrocyte miR-195/497-5p to cartilage maintenance and repair and imply that circadian rhythm disturbances affected by miR-195/497-5p are risk factors for age-related joint diseases such as OA…”

Supplementary Material for: Targeting cartilage miR-195/497 cluster for osteoarthritis treatment regulates the circadian clock by Shi S. (2945916)

“…Conclusion: Our findings identify a regulatory mechanism connecting chondrocyte miR-195/497-5p to cartilage maintenance and repair and imply that circadian rhythm disturbances affected by miR-195/497-5p are risk factors for age-related joint diseases such as OA…”

Supplementary Material for: Targeting cartilage miR-195/497 cluster for osteoarthritis treatment regulates the circadian clock by Shi S. (2945916)

“…Conclusion: Our findings identify a regulatory mechanism connecting chondrocyte miR-195/497-5p to cartilage maintenance and repair and imply that circadian rhythm disturbances affected by miR-195/497-5p are risk factors for age-related joint diseases such as OA…”

Image1_Pilot study shows skin-to-skin care with parents improves heart rate variability in preterm infants in the neonatal intensive care unit.jpeg by Erin Swieter (16999362)

“…SDNN decreased from a median of 10.44 ms before the session to 6.70 ms after being placed back in bed (p < 0.05), with RMSSD decreasing from a median of 6.80 ms before the session to 4.32 ms while being held at the end of 30 min (p < 0.05).…”

HILIC negative mode raw data by Haley Chatelaine (12134238)

“…<div><br></div><div>Extracts (10 uL) were analyzed with HILIC-LC-MS using an Agilent Poroshell 120 HILIC-Z column (2.1 x 100 mm, 1.9 um particle size) at 35 C. Solvent A: 95/5 water/acetonitrile with 0.2% acetic acid and 5 mM ammonium acetate; Solvent B: 95/5 acetonitrile/water with 5 mM ammonium acetate. …”

Fuzzy-logic simulation of the Adaptive Response model. by Andres Kriete (1765)

“…<p>In this simulation of the complete AR-model (see graph in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000820#pcbi-1000820-g004" target="_blank">Figure 4</a>) concentration of reactive molecules stay constant at low levels and oxidized proteins accumulate slower increasing lifespan, different to the model predictions shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000820#pcbi-1000820-g003" target="_blank">Figures 3</a> and <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000820#pcbi-1000820-g005" target="_blank">5</a>. …”

Analysis of scotopic electroretinograms in the <i>Aplp2</i> knockout mice. by Andrei V. Tkatchenko (789098)

“…Lack of <i>Aplp2</i> causes a dose-dependent decrease in the b-wave amplitude (F(2, 18) = 6.9, p = 6.0 × 10⁻³). …”

Therapeutic Non-Toxic Doses of TNF Induce Significant Regression in TNFR2-p75 Knockdown Lewis Lung Carcinoma Tumor Implants by Sharath P. Sasi (541865)

“…Compared to 3 control groups, p75KD/LLC+TNF showed >2-5-fold decreases in tV (p<0.001) and tW (p<0.0001). …”

Conditional Knockout of Serine Racemase in Microglia Alleviates Alzheimer -like Pathology and Behavior by Reducing Neuroinflammation through Enhancing Histone Lactylation by shengzhou Wu (22341388)

“…A conditional knockout of srr, specifically in the microglia of 5XFAD mice, was generated and designated as 5×FAD;Lyz2cre;srrfl/fl. …”

Bar graphs showing the results of the <i>in vivo</i> endonuclease assay. by Tuhin Kumar Guha (2513704)

“…<p>Bar graph shown in panel (<b>A)</b> represents the Student’s t test performed for assessing the significance of the decrease (p < 0.0001) in the number of viable colonies (cfu/mL) for I-CthI-[IIA1]-pET28b (+) and Cth-<i>rns</i>.pACYC184 co-transformed cell lines when grown with the addition of 5 mM MgCl₂ in the LB media compared to the cells grown in only LB media. …”

DataSheet1_Effects of bench press technique variations on musculoskeletal shoulder loads and potential injury risk.PDF by L. Noteboom (18861490)

“…Moreover, scapula retraction, as well as a grip width of <1.5 BAW (p < 0.05), decreased glenohumeral posterior shear force components and rotator cuff activity and may decrease the risk for glenohumeral instability and rotator cuff injuries. …”

Table_3_Chaperones, Membrane Trafficking and Signal Transduction Proteins Regulate Zaire Ebola Virus trVLPs and Interact With trVLP Elements.DOCX by Dong-Shan Yu (5952500)

“…The results demonstrate that RNAi silencing with 11 siRNAs (ANXA5, ARFGAP1, FLT4, GRP78, HSPA1A, HSP90AB1, HSPA8, MAPK11, MEK2, NTRK1, and YWHAZ) decreased the replication efficiency of trVLPs. …”

Table_2_Chaperones, Membrane Trafficking and Signal Transduction Proteins Regulate Zaire Ebola Virus trVLPs and Interact With trVLP Elements.DOCX by Dong-Shan Yu (5952500)

“…The results demonstrate that RNAi silencing with 11 siRNAs (ANXA5, ARFGAP1, FLT4, GRP78, HSPA1A, HSP90AB1, HSPA8, MAPK11, MEK2, NTRK1, and YWHAZ) decreased the replication efficiency of trVLPs. …”

Image_1_Chaperones, Membrane Trafficking and Signal Transduction Proteins Regulate Zaire Ebola Virus trVLPs and Interact With trVLP Elements.TIF by Dong-Shan Yu (5952500)

“…The results demonstrate that RNAi silencing with 11 siRNAs (ANXA5, ARFGAP1, FLT4, GRP78, HSPA1A, HSP90AB1, HSPA8, MAPK11, MEK2, NTRK1, and YWHAZ) decreased the replication efficiency of trVLPs. …”

Table_2_Chaperones, Membrane Trafficking and Signal Transduction Proteins Regulate Zaire Ebola Virus trVLPs and Interact With trVLP Elements.DOCX by Dong-Shan Yu (5952500)

“…The results demonstrate that RNAi silencing with 11 siRNAs (ANXA5, ARFGAP1, FLT4, GRP78, HSPA1A, HSP90AB1, HSPA8, MAPK11, MEK2, NTRK1, and YWHAZ) decreased the replication efficiency of trVLPs. …”

Table_1_Chaperones, Membrane Trafficking and Signal Transduction Proteins Regulate Zaire Ebola Virus trVLPs and Interact With trVLP Elements.DOCX by Dong-Shan Yu (5952500)

“…The results demonstrate that RNAi silencing with 11 siRNAs (ANXA5, ARFGAP1, FLT4, GRP78, HSPA1A, HSP90AB1, HSPA8, MAPK11, MEK2, NTRK1, and YWHAZ) decreased the replication efficiency of trVLPs. …”

Table_3_Chaperones, Membrane Trafficking and Signal Transduction Proteins Regulate Zaire Ebola Virus trVLPs and Interact With trVLP Elements.DOCX by Dong-Shan Yu (5952500)

“…The results demonstrate that RNAi silencing with 11 siRNAs (ANXA5, ARFGAP1, FLT4, GRP78, HSPA1A, HSP90AB1, HSPA8, MAPK11, MEK2, NTRK1, and YWHAZ) decreased the replication efficiency of trVLPs. …”

Image_1_Chaperones, Membrane Trafficking and Signal Transduction Proteins Regulate Zaire Ebola Virus trVLPs and Interact With trVLP Elements.TIF by Dong-Shan Yu (5952500)

“…The results demonstrate that RNAi silencing with 11 siRNAs (ANXA5, ARFGAP1, FLT4, GRP78, HSPA1A, HSP90AB1, HSPA8, MAPK11, MEK2, NTRK1, and YWHAZ) decreased the replication efficiency of trVLPs. …”

Table_1_Chaperones, Membrane Trafficking and Signal Transduction Proteins Regulate Zaire Ebola Virus trVLPs and Interact With trVLP Elements.DOCX by Dong-Shan Yu (5952500)

“…The results demonstrate that RNAi silencing with 11 siRNAs (ANXA5, ARFGAP1, FLT4, GRP78, HSPA1A, HSP90AB1, HSPA8, MAPK11, MEK2, NTRK1, and YWHAZ) decreased the replication efficiency of trVLPs. …”

Table_1_Qingrequzhuo capsule alleviated methionine and choline deficient diet-induced nonalcoholic steatohepatitis in mice through regulating gut microbiota, enhancing gut tight ju... by Shuquan Lv (11897978)

“…In addition, QRQZ treatment decreased the levels of inflammatory cytokines in liver. 16S rRNA sequencing showed that QRQZ affected the diversity of gut microbiota and a f f e c t e d t h e r e l a t i v e a b u n d a n c e s o f D u b o s i e l l a , Lachnospiraceae_NK4A136_group, and Blautiain NASH mice. …”