The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3’-Phosphatase in Spinocerebellar Ataxia Type 3 Pathogenesis by Arpita Chatterjee (529752)

“…Two common dirty ends, 3’-P and 5’-OH, are processed by mammalian polynucleotide kinase 3’-phosphatase (PNKP), a bifunctional enzyme with 3’-phosphatase and 5’-kinase activities. …”

Data_Sheet_1_Phosphorus Leaching From Naturally Structured Forest Soils Is More Affected by Soil Properties Than by Drying and Rewetting.xlsx by Lukas Gerhard (1763269)

“…However, we observed increased inorganic P concentrations and decreased organic P concentrations in leachates after drying to matric potentials above pF 4. …”

Image_1_Transcriptome Analysis Reveals the Mechanism of Natural Ovarian Ageing.jpeg by Lili Chen (66681)

“…Finally, the results of msviper found that transcription factors such as KDM1A, PRDM5, ZNF726, PPARG, FOXJ2, and GLI2 were mainly activated in the 20-29 years group, while VAV1, RUNX3, ZC3H12D, MYCL, and IRF5 were mainly activated in the 30-39 years group and that these transcription factor activities were diagnostic of natural ovarian ageing (AUC: 0.65-0.71).…”

Poor In Utero Growth and Reduced β-Cell Compensation and High Fasting Glucose from Childhood Are Harbingers of Glucose Intolerance in Young Indians by Chittaranjan S Yajnik (11420147)

“…Participants in the highest quintile of fasting glucose at 6 and 12 years had a 2.5- and 4.0-fold higher risk respectively of 18-year glucose intolerance; this finding was replicated in two other cohorts. …”

Table_1_Transcriptome Analysis Reveals the Mechanism of Natural Ovarian Ageing.xlsx by Lili Chen (66681)

“…Finally, the results of msviper found that transcription factors such as KDM1A, PRDM5, ZNF726, PPARG, FOXJ2, and GLI2 were mainly activated in the 20-29 years group, while VAV1, RUNX3, ZC3H12D, MYCL, and IRF5 were mainly activated in the 30-39 years group and that these transcription factor activities were diagnostic of natural ovarian ageing (AUC: 0.65-0.71).…”

Table_1_Mitigating Nitrogen Emissions From Dairy Farming Systems in China.DOCX by Qunchao Fang (8858579)

“…Second, the effects of ammonia (NH₃) abatement technologies on N recycling efficiency (NRE) and N losses are evaluated for the two systems through a scenario analysis. Furthermore, we explore the mitigation potential of integrated crop and dairy production systems using a scenario analysis of a concatenation of mitigation techniques. …”

Metabolic risk factors in young adults infected with HIV since childhood compared with the general population by Elise Arrive (5946236)

“…</p><p>Methods</p><p>We conducted a cross-sectional analysis of data from two populations: (1) COVERTE (ANRS-CO19), a French national cohort of 18 to 30-year-old patients HIV-infected since childhood, and (2) ENNS, a national cross-sectional population-based household survey on nutrition. …”

Table_1_Repurposing of Bromocriptine for Cancer Therapy.docx by Ean-Jeong Seo (3695242)

“…Furthermore, bromocriptine decreased NF-κB activity by a SEAP-driven NF-κB reporter cell assay. …”

DataSheet_2_Transcriptomic and metabolic analyses reveal the potential mechanism of increasing steroidal alkaloids in Fritillaria hupehensis through intercropping with Magnolia off... by Yuanyuan Duan (768972)

“…We proposed a possible steroidal alkaloid biosynthesis pathway, in which 12 differentially expressed genes were identified. …”

DataSheet_1_Transcriptomic and metabolic analyses reveal the potential mechanism of increasing steroidal alkaloids in Fritillaria hupehensis through intercropping with Magnolia off... by Yuanyuan Duan (768972)

“…We proposed a possible steroidal alkaloid biosynthesis pathway, in which 12 differentially expressed genes were identified. …”

Trends in the Incidence of <i>In Situ</i> and Invasive Cervical Cancer by Age Group and Histological Type in Korea from 1993 to 2009 by Chang-Mo Oh (292091)

“…ASRs of ICC declined 3.8% per year, from 19.3 per 100,000 in 1993 to 10.5 per 100,000 in 2009. Although the overall incidence rate of adenocarcinoma remained stable, invasive squamous cell carcinoma showed a decreasing trend (APC −4.2%). …”

Bacterial Colonization of Host Cells in the Absence of Cholesterol by Stacey D. Gilk (208034)

“…In contrast, <em>C. burnetii</em> entry was significantly decreased in −cholesterol MEFs, and also in +cholesterol MEFs when lipid raft-associated α_Vβ₃ integrin was blocked, suggesting a role for lipid rafts in <em>C. burnetii</em> uptake. …”

Small microplastic particles dominate Yangtze River particulate pollution by Yalan Chen (14301098)

“…We observed a ubiquitous presence but spatially and temporally heterogeneous distribution of microplastics at different sampling sites. …”

Identification and Functional Characterization of Novel Phosphorylation Sites in TAK1-Binding Protein (TAB) 1 by Alexander Wolf (191641)

“…It also enhances TAB1-dependent CCL5 secretion in response to IL-1 and increases activity of a post-transcriptional reporter gene, which contains the <em>CCL5</em> 3′ untranslated region. …”

Video_2_Plasma-Treated Water Affects Listeria monocytogenes Vitality and Biofilm Structure.WMV by Oliver Handorf (10713426)

“…Colony-forming units (CFU) were significantly reduced by 4.7 log₁₀ ± 0.29 log₁₀, as well as the metabolic activity decreased by 47.9 ± 9.47% and the cell vitality by 69.5 ± 2.1%, compared to the control biofilms. …”

Data_Sheet_1_EPS Glycoconjugate Profiles Shift as Adaptive Response in Anaerobic Microbial Granulation at High Salinity.PDF by Maria C. Gagliano (5472413)

“…To evaluate this discrepancy, we focused on the microbial and structural dynamics of granules formed in two upflow anaerobic sludge blanket (UASB) reactors treating synthetic wastewater at low (5 g/L Na⁺) and high (20 g/L Na⁺) salinity conditions. …”

Video_1_Plasma-Treated Water Affects Listeria monocytogenes Vitality and Biofilm Structure.WMV by Oliver Handorf (10713426)

“…Colony-forming units (CFU) were significantly reduced by 4.7 log₁₀ ± 0.29 log₁₀, as well as the metabolic activity decreased by 47.9 ± 9.47% and the cell vitality by 69.5 ± 2.1%, compared to the control biofilms. …”

Presentation1_Effects of Chang-Kang-Fang Formula on the Microbiota-Gut-Brain Axis in Rats With Irritable Bowel Syndrome.zip by Xiwen Ling (12518065)

“…After pyrosequencing-based analysis of bacterial 16S rRNA (V3 + V4 region) using rat feces, the Lefse analysis of gut microbiota suggested that CKF treatment could induce structural changes in the gut microbiota, thereby regulating it by decreasing Clostridiales, and the F-B ratio while increasing the levels of Lactobacillus. …”

DCA effects on Pluripotency. by Ana Sofia Rodrigues (491559)

“…A total of 10 independent experiments were analyzed for all experimental conditions resulting in a significant negative impact for CTR w/o LIF and DCA 5 mM. …”

Homogeneity and size of alignment domains depend on podium length. by Martin Hoffmann (52389)

“…Down-regulation of cell migration, i.e. simultaneous decrease in the number of podia from 3 to 2 (offset value from 3.5 to 2.5) and the independent probabilistic podium inactivation rate from 2 to 0/d, occurs linearly in the range between and nearest neighbors. is set to 1∶3 for all simulations except for the one shown in panel B (short podia) in which it is set to 0∶2, i.e. down-regulation of migration already occurs at lower cell densities and results in better short range alignment (compare <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0021960#pone-0021960-g009" target="_blank">Figure 9</a>). is the maximum length of a podium (Modeling methods section E).…”