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we decrease » _ decrease (Expand Search), mean decrease (Expand Search), teer decrease (Expand Search)
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65421
Mean vector fecundity (blue) and fertility (orange) per treatment.
Published 2020“…<p><i>Akirin</i> knockdown mosquitoes had a reduced mean fecundity by 17–25% (one-way ANOVA: <i>p</i><0.01, F = 16.5, DF = 4), and a reduced mean fertility by 23–29% (one-way ANOVA: <i>p</i><0.01, F = 63.4, DF = 4), when compared to the control treatments. …”
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65422
Tau exon 10 alternative splicing and tauopathies-1
Published 2011“…The first half of exon 10 has three exonic splicing enhancers (SC35-like, PPE and ACE). A central exon splicing silencer (ESS) separates the 5' ESE elements from a less characterized ESE at the 3'-end of exon 10. …”
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65423
The distribution of migratory microglial cells and the association between mRNA levels and the number of migrated microglial cells during retinal degeneration in RCS rats.
Published 2013“…(B) mRNA levels of MFG-E8 and integrin αυ showed more significant linear regression with the migration of microglial cells than the integrin β5. (C) mRNA level of CD11b was significantly associated with the migration of microglial cells and IL-1β and TNF-α showed a modestly linear regression, but the association between mRNA levels of MCP-1 and microglial cells was slightly negative, which might be owed to a dramatic reduction of apoptotic cells and a possible decrease in the phagocytic activity (or requirement) of microglial cells in the ONL.…”
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65424
Tau exon 10 alternative splicing and tauopathies-0
Published 2011“…The first half of exon 10 has three exonic splicing enhancers (SC35-like, PPE and ACE). A central exon splicing silencer (ESS) separates the 5' ESE elements from a less characterized ESE at the 3'-end of exon 10. …”
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65425
Ultra-high performance pastes under pressure curing
Published 2019“…They showed the influence of pressurizing on the development of a compact and homogeneous matrix, but with an increase in microporosity and a decrease in the amount of hydration products formed. …”
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65426
Prostaglandin E(PGE) does not affect total proteoglycan release
Published 2011“…<p><b>Copyright information:</b></p><p>Taken from "Prostaglandin PGEat very low concentrations suppresses collagen cleavage in cultured human osteoarthritic articular cartilage: this involves a decrease in expression of proinflammatory genes, collagenases and , a gene linked to chondrocyte hypertrophy"</p><p>http://arthritis-research.com/content/9/4/R75</p><p>Arthritis Research & Therapy 2007;9(4):R75-R75.…”
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65427
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65428
Impact of combined oil-in-water emulsions and particulate suspensions on ceramic membrane fouling and permeability recovery
Published 2019“…The addition of 1500 mg·L−1 of bentonite to a 10 vol.% emulsion resulted in a permeability decrease of 3.5–5 times over that recorded for the emulsion, and 8–36 times lower than that of the bentonite suspension. …”
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65429
Effect of the NTSR1 agonist and antagonist in AMY on CFS.
Published 2014“…<b><i>E</i></b>, Bilateral infusions of a NTSR1 agonist (PD149613) dissolved in 0.5 µl of saline into AMY produced a significant decrease in the freezing rate at a concentration of 100 µM at the second exposure (n = 7 – 8 rats per all groups; *<i>p</i><0.05 vs. saline or DMSO control). …”
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65430
Effect of ABCG2 overexpression on the expression of SLC transporter genes and MPP, glucose and glutamine transport.
Published 2015“…<p>Down-regulation of SLC transporter expression (SLC22A1, SLC22A3, SLC2A1, SLC38A2, SLC3A2, SLC7A5, and SLC7A6) in HEK293/R2 cells versus HEK293 was evaluated by PCR drug transporter array (A). …”
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65431
Image_2_Global Characterization of Peripheral B Cells in Parkinson’s Disease by Single-Cell RNA and BCR Sequencing.jpeg
Published 2022“…Finally, we found a marked clonal expanded memory B cell population in PD patients, up-regulating both MHC II genes (HLA-DRB5, HLA-DQA2 and HLA-DPB1) and transcription factor activator protein 1 (AP-1), suggesting that the antigen presentation capacity of B cells was enhanced and B cells were activated in PD patients. …”
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65432
Table_2_Global Characterization of Peripheral B Cells in Parkinson’s Disease by Single-Cell RNA and BCR Sequencing.xlsx
Published 2022“…Finally, we found a marked clonal expanded memory B cell population in PD patients, up-regulating both MHC II genes (HLA-DRB5, HLA-DQA2 and HLA-DPB1) and transcription factor activator protein 1 (AP-1), suggesting that the antigen presentation capacity of B cells was enhanced and B cells were activated in PD patients. …”
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65433
Image_1_Global Characterization of Peripheral B Cells in Parkinson’s Disease by Single-Cell RNA and BCR Sequencing.jpeg
Published 2022“…Finally, we found a marked clonal expanded memory B cell population in PD patients, up-regulating both MHC II genes (HLA-DRB5, HLA-DQA2 and HLA-DPB1) and transcription factor activator protein 1 (AP-1), suggesting that the antigen presentation capacity of B cells was enhanced and B cells were activated in PD patients. …”
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65434
Silencing BRE Expression in Human Umbilical Cord Perivascular (HUCPV) Progenitor Cells Accelerates Osteogenic and Chondrogenic Differentiation
Published 2013“…<i>BRE</i>-silencing negatively regulated <i>OCT4</i>, <i>FGF5</i> and <i>FOXO1A</i>. <i>BRE</i>-silencing also altered the expression of epigenetic genes and components of the TGF-β/BMP and FGF signaling pathways which are crucially involved in maintaining stem cell self-renewal. …”
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65435
Table_1_Global Characterization of Peripheral B Cells in Parkinson’s Disease by Single-Cell RNA and BCR Sequencing.xlsx
Published 2022“…Finally, we found a marked clonal expanded memory B cell population in PD patients, up-regulating both MHC II genes (HLA-DRB5, HLA-DQA2 and HLA-DPB1) and transcription factor activator protein 1 (AP-1), suggesting that the antigen presentation capacity of B cells was enhanced and B cells were activated in PD patients. …”
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65436
IPA analysis reveals oxidative phosphorylation pathway.
Published 2012“…HF <i>Acads+/+</i> mice, we found significantly decreased expression of ATP synthase genes in mitochondrial complex 5 (top panel), consistent with a state of decreased energy availability.…”
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65437
Image1_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.TIF
Published 2024“…Introduction<p>Monoiodoacetate (MIA)-induced osteoarthritis (OA) is the most commonly used rodent model for testing anti-OA drug candidates. Herein, we investigated the effects of our patented multitarget drug candidate SZV-1287 (3-(4,5-diphenyl-1,3-oxazol-2-yl) propanal oxime) that is currently under clinical development for neuropathic pain and characterized the mouse model through complex functional, in vivo imaging, and morphological techniques.…”
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65438
Table1_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.docx
Published 2024“…Introduction<p>Monoiodoacetate (MIA)-induced osteoarthritis (OA) is the most commonly used rodent model for testing anti-OA drug candidates. Herein, we investigated the effects of our patented multitarget drug candidate SZV-1287 (3-(4,5-diphenyl-1,3-oxazol-2-yl) propanal oxime) that is currently under clinical development for neuropathic pain and characterized the mouse model through complex functional, in vivo imaging, and morphological techniques.…”
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65439
Image3_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.TIF
Published 2024“…Introduction<p>Monoiodoacetate (MIA)-induced osteoarthritis (OA) is the most commonly used rodent model for testing anti-OA drug candidates. Herein, we investigated the effects of our patented multitarget drug candidate SZV-1287 (3-(4,5-diphenyl-1,3-oxazol-2-yl) propanal oxime) that is currently under clinical development for neuropathic pain and characterized the mouse model through complex functional, in vivo imaging, and morphological techniques.…”
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65440
Image2_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.TIF
Published 2024“…Introduction<p>Monoiodoacetate (MIA)-induced osteoarthritis (OA) is the most commonly used rodent model for testing anti-OA drug candidates. Herein, we investigated the effects of our patented multitarget drug candidate SZV-1287 (3-(4,5-diphenyl-1,3-oxazol-2-yl) propanal oxime) that is currently under clinical development for neuropathic pain and characterized the mouse model through complex functional, in vivo imaging, and morphological techniques.…”