Image 5_Cellular interactions and Ion channel signatures in atrial fibrillation remodeling: insights from single-cell analysis and machine learning.tif by Bin He (75597)

“…In the AF group, the proportions of EF, APF, and LBCs were increased, whereas the proportion of EC was decreased; by contrast, the SR group displayed a higher proportion of EC. …”

Effects of drug treatments on culture cells and embryos. by Xiaowen Jiang (8291814)

Prenatal Air Pollution Exposure and Early Cardiovascular Phenotypes in Young Adults by Carrie V. Breton (74382)

“…For example, a 2 SD increase in prenatal PM_2.5 was associated with CAS indices, including a 5% increase (β = 1.05, 95% CI 1.00–1.10) in carotid stiffness index beta, a 5% increase (β = 1.05, 95% CI 1.01–1.10) in Young’s elastic modulus and a 5% decrease (β = 0.95, 95% CI 0.91–0.99) in distensibility. …”

Image_5_Transcatheter Aortic Valve Implantation for Severe Bicuspid Aortic Stenosis – 2 Years Follow up Experience From India.jpg by Vijay Kumar (377076)

“…The Sievers type 1 included 78.5%, type 0 were 21.4% of the cases and there was no case of type 2 in the study. …”

Image_5_CRISPR/Cas9-Mediated Knockout of Galactinol Synthase-Encoding Genes Reduces Raffinose Family Oligosaccharide Levels in Soybean Seeds.JPEG by Huy Le (9856877)

Table_5_New evidence for the effect of type 2 diabetes and glycemic traits on testosterone levels: a two-sample Mendelian randomization study.xlsx by Chengyang Jiang (1540369)

CD8 and CD4 Epitope Predictions in RV144: No Strong Evidence of a T-Cell Driven Sieve Effect in HIV-1 Breakthrough Sequences from Trial Participants by Kalpana Dommaraju (650755)

“…Comparisons between the vaccine and placebo arm did not reveal robust evidence for a T cell driven sieve effect, although some differences were noted in Env-V2 (0.022≤p-value≤0.231). The paucity of CD8 T cell responses identified following RV144 vaccination, with no evidence for V2 specificity, considered together both with the association of decreased infection risk in RV 144 participants with V-specific antibody responses and a V2 sieve effect, lead us to hypothesize that this sieve effect was not T cell specific. …”

CRISPR <i>kcnk5b</i> KO strategy, targeting efficiency of endogenous locus and Kcnk5b mutants. by Xiaowen Jiang (8291814)

Early and late pulmonary effects of nebulized LPS in mice: An acute lung injury model by Natália de Souza Xavier Costa (4474648)

“…</p><p>Results</p><p>The LPS 24h group showed increased pro-inflammatory cytokine levels, intense cell influx, increased total septal volume, septal thickening and decreased surface density of the alveolar septa. The LPS 5w group showed persistent lung inflammation, septal thickening, increased total lung volume, accentuated collagen deposition, especially of collagen type I, and decreased MMP-2 protein expression.…”

Data_Sheet_2_Efficacy and safety of endothelin receptor antagonists, phosphodiesterase type 5 Inhibitors, and prostaglandins in pediatric pulmonary arterial hypertension: A network... by Fen Cao (4496014)

“…To compare the effectiveness and safety of endothelin receptor antagonists (ERAs), phosphodiesterase type 5 Inhibitors (PDE-5i), and prostaglandins (ProA) in the treatment of pediatric PAH, we investigated six hemodynamic parameters, four respiratory parameters, intensive care unit (ICU) stay duration, length of hospital stay, and two safety outcomes.…”

Data_Sheet_1_Efficacy and safety of endothelin receptor antagonists, phosphodiesterase type 5 Inhibitors, and prostaglandins in pediatric pulmonary arterial hypertension: A network... by Fen Cao (4496014)

“…To compare the effectiveness and safety of endothelin receptor antagonists (ERAs), phosphodiesterase type 5 Inhibitors (PDE-5i), and prostaglandins (ProA) in the treatment of pediatric PAH, we investigated six hemodynamic parameters, four respiratory parameters, intensive care unit (ICU) stay duration, length of hospital stay, and two safety outcomes.…”

Data_Sheet_3_Efficacy and safety of endothelin receptor antagonists, phosphodiesterase type 5 Inhibitors, and prostaglandins in pediatric pulmonary arterial hypertension: A network... by Fen Cao (4496014)

“…To compare the effectiveness and safety of endothelin receptor antagonists (ERAs), phosphodiesterase type 5 Inhibitors (PDE-5i), and prostaglandins (ProA) in the treatment of pediatric PAH, we investigated six hemodynamic parameters, four respiratory parameters, intensive care unit (ICU) stay duration, length of hospital stay, and two safety outcomes.…”

Data_Sheet_4_Efficacy and safety of endothelin receptor antagonists, phosphodiesterase type 5 Inhibitors, and prostaglandins in pediatric pulmonary arterial hypertension: A network... by Fen Cao (4496014)

“…To compare the effectiveness and safety of endothelin receptor antagonists (ERAs), phosphodiesterase type 5 Inhibitors (PDE-5i), and prostaglandins (ProA) in the treatment of pediatric PAH, we investigated six hemodynamic parameters, four respiratory parameters, intensive care unit (ICU) stay duration, length of hospital stay, and two safety outcomes.…”

Fig 3 - by Anna Rivera Roy (19193874)

Schematic overview of molecular processes altered during disease progression in the SN of PD, identified using transcriptome analysis. by Anke A. Dijkstra (756877)

“…In addition, we observed down regulation of mRNA levels of the upstream regulators in mTOR pathway. …”

Estimated demographic history in four simple demographic scenarios with seed banking where <i>μ</i> = 2.5 × 10⁻⁹. by Thibaut Paul Patrick Sellinger (8677419)

“…We have <i>β</i> = 1 (red), 0.5 (blue), 0.2 (green) and 0.1 (purple). …”

Example of camera trap setup. by Anna Rivera Roy (19193874)

Data_Sheet_1_Epidemiological Consequences of Viral Interference: A Mathematical Modeling Study of Two Interacting Viruses.PDF by Lubna Pinky (2794879)

“…We find that population-level effect of viral block is a decrease in the number of people infected with the suppressed virus. …”

Image_1_RETRACTED: The Effect of MCM3AP-AS1/miR-211/KLF5/AGGF1 Axis Regulating Glioblastoma Angiogenesis.PDF by Chunqing Yang (6271727)

“…Besides, in this study we found that MCM3AP-AS1 knockdown decreased KLF5 and AGGF1 expression by upregulating miR-211. …”

Image_2_The Effect of MCM3AP-AS1/miR-211/KLF5/AGGF1 Axis Regulating Glioblastoma Angiogenesis.PDF by Chunqing Yang (6271727)

“…Besides, in this study we found that MCM3AP-AS1 knockdown decreased KLF5 and AGGF1 expression by upregulating miR-211. …”