Supplementary Material for: Expression and Clinical Implication of Autophagy-Associated Protein p62 in Osteosarcoma by Ma H. (4137913)

“…The TMA also showed differential expression in osteosarcoma tissues. Seventy-five of 79 (94.9%) patient tissues exhibited p62 immunostaining, ranging from no staining (4 of 97, 5.1%) to 1+ staining (40 of 79, 50.6%), 2+ staining (17 of 79, 21.5%), and 3+ staining (18 of 79, 22.8%). …”

Analysis of the Microbial Community in an Acidic Hollow-Fiber Membrane Biofilm Reactor (Hf-MBfR) Used for the Biological Conversion of Carbon Dioxide to Methane by Hyun Chul Shin (840172)

“…CO₂ and H₂ were diffused into the culture medium through the membrane without bubble formation in the Hf-MBfR, which was operated at pH 4.5–5.5 over 70 days. Focusing on the presence of hydrogenotrophic methanogens, we analyzed the structure of the microbial community in the reactor. …”

Mutation spectrum of eUCR41 in sample CC. by Anna De Grassi (62033)

“…Two ranges of substitution frequency are shown: 40.5%–2.5% and <1.0%, since no substitution was detected in the range 2.5%–1.0%. …”

Gains in Dynamic Range via Increasing Number of Dilutions—Constant Available Partitioning. by Nivedita Majumdar (711576)

“…Benefits to Dynamic Range are slight at high levels of precision (e.g., 5%) and are even seen to occasionally decrease as subsets increase (e.g., 5% precision between 5 and 6 subsets). …”

Figure S1 - Isoflurane Reversibly Destabilizes Hippocampal Dendritic Spines by an Actin-Dependent Mechanism by Jimcy Platholi (605486)

“…Representative images show time-lapse of eGFP fluorescence showing a time-dependent decrease in spine area (top panel- Control; bottom panel- Isoflurane). …”

<i>fat-6</i> mRNA levels are induced through NHR-80 in <i>glp-1(e2141ts)</i> animals. by Jérôme Goudeau (228021)

“…Relative to <i>glp-1(e2141ts)</i> mutants, <i>K04A8.5</i> is decreased 6.4-fold in <i>daf-16(mu86);glp-1(e2141ts)</i> mutants (<i>p</i><0.01) and 1.4-fold in <i>glp-1(e2141ts);nhr-80(tm1011)</i> double mutants (Wilcoxon rank-sum test <i>p</i> value is non-significant). …”

Impaired growth of DC lymphocytes in cell culture. by Larisa Pereboeva (322533)

“…<p>(A) Control (n = 5) and DC (n = 5) lymphocytes were stimulated with CD3/CD28 beads at day 1 and cultured in IL-2 supplemented medium. …”

Fetal survival after LPS administration. by Maide Ozen (6551636)

“…<p>(<b>A</b>) LPS at a dose of 90 ug/kg (LPS90) was administered i.p. to pregnant Wt or Het dams at E15.5 (control or Con, n = 9; LPS90, n = 8, sacrificed at E16.5). …”

Impact of mutations in Toll-like receptor pathway genes on esophageal carcinogenesis by Daffolyn Rachael Fels Elliott (4039580)

“…Through interrogating whole genome sequencing data from 171 EAC patients, we showed that non-synonymous mutations collectively affect the TLR pathway in 25/171 (14.6%, PathScan p = 8.7x10^-5) tumors. …”

Table_1_Higher levels of serum α-Klotho are longitudinally associated with less central obesity in girls experiencing weight gain.pdf by Gemma Carreras-Badosa (5856032)

“…</p>Subjects and methods<p>We studied a cohort of 208 apparently healthy school-age children (107 girls and 101 boys) assessed at baseline (mean age 8.5 ± 1.8 years) and at follow-up 4 years later. …”

Aluminum toxicity reduces the nutritional efficiency of macronutrients and micronutrients in sugarcane seedlings by Carolina Eggers Borges (10398678)

Timed data for onset and survival. by Alexandre Henriques (359791)

“…(A) Onset of weight decrease was defined as a drop of 5% of the mouse maximal weight. …”

Short-term tissue decomposition alters stable isotope values and C:N ratio, but does not change relationships between lipid content, C:N ratio, and Δδ¹³C in marine anima... by Matthew J. Perkins (544054)

“…We, therefore, recommend that specimens of marine animals should be kept in ice during sample preparation for a short-term, as it is an effective means for minimizing changes of the stable isotope measures in their tissue.…”

Variance-sensitivity poster 061119.pdf by Thomas Ray Haaland (7258370)

ACTIIR Inhibition in Murine Ischemic Heart Failure - Supplementary Figures by Estibaliz Castillero (6715277)

Pollen-based Holocene vegetation reconstruction.xlsx by Yuanhao Sun (12697028)

“…In the Daihai basin, the vegetation cover changed relatively little, maintaining values of 45–50%, and only increased during the interval of 8–5.1 ka, when it attained a maximum of 67%. In the Gonghai area, the vegetation cover remained at a higher level at 70–80% for an extended interval, before decreasing substantially to 58% after 1.4 ka. …”

Table_1_Sex-Differences and Associations Between Complement Activation and Synovial Vascularization in Patients with Late-Stage Knee Osteoarthritis.docx by Emily U. Sodhi (12610462)

“…Males had higher sC5b-C9 compared to females. Additionally, males with high C5 had a higher synovial fluid concentration of sC5b-C9 compared to males with low C5. …”

Diploid sexual populations evolve mutational robustness at lower mutation rate. by Kerry J. Kim (266640)

“…<p>Plots show results of 38 simulations to 5,000 generations with μ = 0.005, smoothed with a sliding window of 100 generations. …”

Table_1_Effect and Safety of Adding Metformin to Insulin Therapy in Treating Adolescents With Type 1 Diabetes Mellitus: An Updated Meta-Analysis of 10 Randomized Controlled Trials.... by Ying Liu (18461)

“…Results suggested that metformin significantly decreased the HbA1c level at 12 months (mean difference [MD])=-0.50, 95% confidence interval [CI]=-0.61 to -0.39, P < 0.01); BMI (kg/m²) at 3 months (MD=-1.05, 95%CI=-2.05 to -0.05, P=0.04); BMI z-score at 6 months (MD=-0.10, 95%CI=-0.14 to -0.06, P<0.01); and TIDD at 3 (MD=-0.13, 95%CI=-0.20 to -0.06, P<0.01), 6 (MD=-0.18, 95%CI=-0.25 to -0.11, P<0.01), and 12 (MD=-0.42, 95%CI=-0.49 to -0.35, P<0.01) months but significantly increased the risk of hypoglycemia events (risk ratio [RR]=3.13, 95%CI=1.05 to 9.32, P=0.04) and GIAEs (RR=1.64, 95%CI=1.28 to 2.10, P<0.01). …”

Table_2_Effect and Safety of Adding Metformin to Insulin Therapy in Treating Adolescents With Type 1 Diabetes Mellitus: An Updated Meta-Analysis of 10 Randomized Controlled Trials.... by Ying Liu (18461)

“…Results suggested that metformin significantly decreased the HbA1c level at 12 months (mean difference [MD])=-0.50, 95% confidence interval [CI]=-0.61 to -0.39, P < 0.01); BMI (kg/m²) at 3 months (MD=-1.05, 95%CI=-2.05 to -0.05, P=0.04); BMI z-score at 6 months (MD=-0.10, 95%CI=-0.14 to -0.06, P<0.01); and TIDD at 3 (MD=-0.13, 95%CI=-0.20 to -0.06, P<0.01), 6 (MD=-0.18, 95%CI=-0.25 to -0.11, P<0.01), and 12 (MD=-0.42, 95%CI=-0.49 to -0.35, P<0.01) months but significantly increased the risk of hypoglycemia events (risk ratio [RR]=3.13, 95%CI=1.05 to 9.32, P=0.04) and GIAEs (RR=1.64, 95%CI=1.28 to 2.10, P<0.01). …”