The expression of proteins involved in iron transport in SK-Mel-5 cells indicates a decrease in iron stores. by Sarah Straud (245572)

“…Relative to HeLa cells, SK-Mel-5 have decreased expression of transferrin receptor and ferritin and a large increase in expression of the iron efflux protein ferroportin. …”

Reproductive transition paralleled a significant decrease in LDH5 and LDH1 expressions in nonTg hippocampus. by Fan Ding (302565)

“…<p>A. NonTg hippocampus demonstrated a an age-related decrease in LDH5 expression from 6 to 15 months of age, which was significant between 6 and 9, 9 and 12 months of age. …”

IL-4 Causes Hyperpermeability of Vascular Endothelial Cells through Wnt5A Signaling by Tom Skaria (2733439)

“…Our study identifies Wnt5A as a novel marker of IL-4 activated vascular endothelium and demonstrates a critical role for Wnt5A in mediating IL-4 induced endothelial barrier dysfunction. …”

Image5_Analysis of Geometric and Hemodynamic Profiles in Rat Arteriovenous Fistula Following PDE5A Inhibition.tif by Hannah Northrup (5938436)

“…To test our hypothesis, we used the PDE5A inhibitor sildenafil to treat AVFs in a rat model and performed magnetic resonance imaging (MRI) based computational fluid dynamics (CFD) to generate a detailed spatial profile of hemodynamics in AVFs. 90 mg/kg of sildenafil was administered to rats in their drinking water for 14 days. …”

Table_5_Arabidopsis Histone Methyltransferase SUVH5 Is a Positive Regulator of Light-Mediated Seed Germination.DOCX by Dachuan Gu (6790856)

“…Here, we identified SUVH5, a histone H3 lysine 9 methyltransferase, as a positive regulator in light-mediated seed germination in Arabidopsis. …”

Chemokines, with the exception of CXCL1 and MCP-1, decrease acutely following 5 Gy IR. by Jordan A. Gunning (18143970)

Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…We describe the discovery of a thioester-containing glucocorticoid receptor modulator (GRM) payload and the corresponding antibody–drug conjugate (ADC). …”

Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…We describe the discovery of a thioester-containing glucocorticoid receptor modulator (GRM) payload and the corresponding antibody–drug conjugate (ADC). …”

PI3K activity is required for induction of cerebellar LTP. by Claire Jackson (362873)

A Single Amino Acid Deletion (ΔF1502) in the S6 Segment of Ca_V2.1 Domain III Associated with Congenital Ataxia Increases Channel Activity and Promotes Ca²⁺ In... by Maria Isabel Bahamonde (840859)

“…Here, we report a second case of congenital ataxia linked to the ΔF1502 α_1A mutation, detected by whole-exome sequencing, and analyze its functional consequences on Ca_V2.1 human channels heterologously expressed in mammalian tsA-201 HEK cells, using the physiological permeant ion Ca²⁺. …”

Knockdown of AR expression decreases the efficiency of KSHV infection in endothelial cells. by Xing Wang (154377)

“…(g, h) Knockdown of AR and EphA2 expression decreases nuclear LANA expression in SLK cells, as determined by an immunofluorescence assay and quantitative analysis by Image J software. …”

The <i>AtTIFY10a/b</i> knockout mutant <i>Arabidopsis</i> showed decreased alkaline tolerance at the seed germination stage. by Dan Zhu (139675)

Identification of a Hydroxypyrimidinone Compound (<b>21</b>) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure by Wei Meng (505670)

“…Due to the increased polarity at C2, the permeability for these compounds decreased. Further adjustment of the polarity by replacing the N1 2,6-dimethoxyphenyl group with a 2,6-diethylphenyl group and reoptimization for the potency of the C5 pyrroloamides resulted in potent compounds with improved permeability. …”

Identification of a Hydroxypyrimidinone Compound (<b>21</b>) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure by Wei Meng (505670)

“…Due to the increased polarity at C2, the permeability for these compounds decreased. Further adjustment of the polarity by replacing the N1 2,6-dimethoxyphenyl group with a 2,6-diethylphenyl group and reoptimization for the potency of the C5 pyrroloamides resulted in potent compounds with improved permeability. …”

Identification of a Hydroxypyrimidinone Compound (<b>21</b>) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure by Wei Meng (505670)

“…Due to the increased polarity at C2, the permeability for these compounds decreased. Further adjustment of the polarity by replacing the N1 2,6-dimethoxyphenyl group with a 2,6-diethylphenyl group and reoptimization for the potency of the C5 pyrroloamides resulted in potent compounds with improved permeability. …”

Classification and regression tree: CYP3A5 phenotype discriminates between cases and tolerants (EM = normal metabolizers, IM and PM = decrease function, UM and UMH = increase function). by Luciana Kase Tanno (785410)

“…<p>Classification and regression tree: CYP3A5 phenotype discriminates between cases and tolerants (EM = normal metabolizers, IM and PM = decrease function, UM and UMH = increase function).…”

Exploring reopening strategies for a high range in disease transmission <i>v</i>_<i>r</i> with high testing capacity. by Mackenzie Dalton (14093874)

<i>Fkbp5</i> DNA methylation decreases with age in mice. by Jonathan J. Sabbagh (626366)

S5 Fig - by Pablo Capilla-Lasheras (5209658)

Table_1_When and Why Did Human Brains Decrease in Size? A New Change-Point Analysis and Insights From Brain Evolution in Ants.XLSX by Jeremy M. DeSilva (7247009)

“…<p>Human brain size nearly quadrupled in the six million years since Homo last shared a common ancestor with chimpanzees, but human brains are thought to have decreased in volume since the end of the last Ice Age. …”