Simulations Demonstrating the Effects of Varying the Degree of Resistance on Treatment Success Rates by Marcel E Curlin (32388)

“…<p>As in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0030133#pcbi-0030133-g005" target="_blank">Figures 5</a> and <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0030133#pcbi-0030133-g006" target="_blank">6</a>, (A) and (C) demonstrate success rates as the duration of induction therapy is increased, and (B) and (D) demonstrate success rates over a range of induction therapy/therapy intensification start times. …”

Modeling the RA Morphogen Gradient by Richard J White (82003)

“…Values of parameters that differed between panels were β = 1 ([A–E] and solid curve in [G]) or 0.5 ([F], [H], and dashed curve in [G]); <i>x</i>_f = 400 μm ([A–C] and [F–H]) or 450 μm (D–E); <i>f</i>₀ = 0 (B), 400 ([A], [C], [F–H], and solid curves in [D] and [E]), or 1,100 (dashed curves in [D] and [E]); <i>k</i>_deg = 500 sec⁻¹ ([A] and [C–G]) or 0.03 sec⁻¹ (B); <i>k</i>_max = 0.001 ([A] and [C–G]) or 4 (B); <i>V</i>(<i>x</i>) = 5 for <i>x</i> > <i>x</i>_f – 40, zero otherwise ([A], [D], [E], and solid curves in [B], [C], and [G]), 2.5 for <i>x</i> > <i>x</i>_f – 40, zero otherwise (dashed curves in [B] and [C]), 0.2 for all <i>x</i> ([F], dashed curve in [G], and solid curve in [H]), or 0.1 for all <i>x</i> (dashed curve in [H]).…”

Data_Sheet_1_The Responses of Germ-Free Zebrafish (Danio rerio) to Varying Bacterial Concentrations, Colonization Time Points, and Exposure Duration.docx by Fang Tan (353838)

“…The results indicated that the final bacteria concentrations ranging from 10² to 10⁴ CFU/ml did not cause any mortality when GF mono-associated larvae were exposed to either E. coli DH5α or B. subtilis WB800N at 3 or 5 dpf, while concentrations ranging from 10⁶ to 10⁷ CFU/ml increased the mortality, particularly for 5 dpf owing to the decrease in dissolved oxygen level. …”

HepR21 cells have increased resilience to nutrient deprivation compared to HepG2 cells. by Paramita Saha (473954)

“…A set of cells were kept as control. The survivability of HepR21 cells was found to remain unaffected while HepG2 cells were highly sensitive upon prolonged starvation with an overall 50% decrease in growth after 36 h of starvation. …”

DataSheet_1_Treatment With Lipopolysaccharide Induces Distinct Changes in Metabolite Profile and Body Weight in 129Sv and Bl6 Mouse Strains.docx by Maria Piirsalu (8627697)

“…According to the general linear model analysis (GLM), the 1.5 h LPS challenge in Bl6 caused a decrease of propionylcarnitine (C3), glucogenic amino acids, and acetylornithine (Ac-Orn), whereas the response of 129Sv included decreased concentrations of short-chain acylcarnitines (SCACs), citrulline, and elevation of glycerophospholipid (PCaa C42:0) and sphingolipid [SM(OH)C16:1]. 24 h after LPS administration, robust alterations in lipid profile were observed in both strains. …”

Infiltration of blood clots by cancer cells. by Stephanie Rossnagl (553093)

“…(F) Evaluation of cancer cell numbers when injected 5 minutes after clot induction showed a significant decrease in the number of cancer cells detected in the bone marrow at 1 hour after clot induction (p<0.05) but not at later time points (4, 24 and 48 hours after clot induction) (p = ns). n = 4–8 per time point.…”

Heterotrophic cell growth and dry cell yield of <i>Rhodovulum sulfidophilum</i> in artificial seawater (ASW) based growth medium of different salinities, wherein 100% corresponds t... by Shamitha Rao Morey-Yagi (19779981)

“…<p><b>a,</b> Growth curve and <b>b,</b> dry cell yield (g L^-1) of <i>R. sulfidophilum</i> in ASW supplemented with 0.1% yeast extract and 0.5% peptone, and <b>c,</b> dry cell yield (g L^-1) of <i>R. sulfidophilum</i> in ASW supplemented with 1 mM sodium acetate and 2.5 mM sodium thiosulfate in decreasing concentrations of ASW, i.e., 100%, 90%, 80%, 70%, 60%, and 50% which correspond to 3%, 2.7%, 2.4%, 2.1%, 1.8%, and 1.5% salinities respectively. …”

Image_1_Assessment of Epigenetic and Phenotypic Variation in Populus nigra Regenerated via Sequential Regeneration.tif by Weixi Zhang (1626823)

“…We detected a significant difference in methylation levels between first regeneration regenerated plants (G1) and those of the other four generations (G2–G5); there were no significant differences among the four later generations. …”

Data Sheet 1_Mechanical property changes of glial LC and RGC axons in response to high intraocular pressure.docx by Bochao Ma (14572143)

“…</p>Results<p>Compared to the control group, the Young's modulus of the glial LC decreased by 35.5%, 74.2%, and 80.6% at 4, 8, and 12 weeks of elevated IOP, respectively. …”

microRNA-14 as an efficient suppressor to switch off ecdysone production after ecdysis in insects by Kang He (189002)

“…<p>The precise increase and decrease of hormone ecdysone are critical for accurate development in insects. …”

Conditional ablation of <i>Tra2b</i> causes perinatal lethality and disturbed cortical patterning in mice. by Markus Storbeck (191895)

“…Cells of the ventricular and subventricular zones of the cortex show strongest decrease in staining intensity (black arrowhead). Scale bar equals 400 µm; ctx, cortex; th, thalamus; cpt, caudoputamen; cp, cortical plate; iz, intermediate zone; svz, subventricular zone; vz, ventricular zone; sn, septal nuclei; 3v, third ventricle; lv, lateral ventricle; pc, choroid plexus.…”

Effects of COAM co-treatment on LPS-induced systemic inflammation in the liver. by Sandra Li (197874)

“…Neutrophil, elastase and histones were measured in five FOV/mouse, n = 5–7 animals per group; *<i>P</i><0.05.…”

Effect of CYP27B1 silencing on 1,25OH₂D₃ generation. by Kaining Liu (294608)

“…<p>hGF and hPDLC from donors 2, 3 and 5 were treated with 25OHD₃ at various concentrations indicated in the figure for 48 h after transfection with the siRNA oligonucleotide for CYP27B1 or a non-silencing control and 1,25OH₂D₃ production was measured in (A) supernatants and (B) cell lysates. …”

MDSC depletion augmented the tumor cell apoptosis and increased anti-angiogenic but reduced pro-angiogenic marker expression in tumors. by Minu K. Srivastava (315754)

“…<b><i>4E–H</i></b><i>,</i> Relative pro-angiogenic and anti-angiogenic marker expression in tumors by QRTPCR normalized by β-actin. MDSC depletion decreased pro-angiogenic (VEGF-a, CXCL2, CXCL5, Ang1 and Ang2) (<b>4E–F</b>) but increased anti-angiogenic (CXCL9 and CXCL10) (<b>4G</b>) and CXCR3 (<b>4H</b>) expression in the tumors. …”

Supplementary Material for: Local recurrence in choroidal melanomas following Robotic assisted Radiosurgery (CyberKnife) by Schmelter V. (14069160)

“…Local recurrence occurred after 42.1 months post CyberKnife treatment (mean; range: 5 – 100 months). 14 out of 74 patients (18.9%) died during follow-up. …”

Figure S1 - Targeting Lysophosphatidic Acid Signaling Retards Culture-Associated Senescence of Human Marrow Stromal Cells by Masahiko Kanehira (183764)

“…<p><b>Prevention of decreased self-renewal capacity associated with senescence was also observed in Ki16425-treated human MSCs from different donors.…”

Effects of β₃-AR Abs on intracellular calcium transient ([Ca²⁺]_iT) and I_Ca-L in isolated adult rat cardiomyocytes. by Jin Wang (29560)

“…<p>A. Representative [Ca²⁺]_iT profile in isolated rat cardiomyocytes demonstrating decreased [Ca²⁺]_iT induced by β₃-AR Abs (0.1 μmol/L). …”

Differential Development of Human Brain White Matter Tracts by Davide Imperati (207531)

“…Specifically, using a cross-sectional sample comprising 144 healthy individuals (7 to 48 years old), we applied k-means cluster analysis to separate white matter voxels based on their age-related trajectories of fractional anisotropy. …”

Topographic outcomes after corneal collagen crosslinking in progressive keratoconus: 1-year follow-up by Mauro C. Tiveron Jr (5760554)

“…The mean age of our study population was 19.9 ± 5.61 years. …”

siRNA knockdown of HOTAIR and effect on PCa cell viability. by Takeshi Chiyomaru (140914)

“…<p>(A) HOTAIR expression levels in PCa cell lines (PC3 and DU145) were determined by real-time PCR at 96 hours after transient transfection of siRNA. …”