Data_Sheet_1_The effect and safety of corticosteroid treatment for severe community-acquired pneumonia: a meta-analysis of randomized controlled trials.docx by Yang Chen (9737)

“…Overall, our meta-analysis exhibited that corticosteroids may considerably lower short-term mortality when compared to control treatment [6 studies (1,582 patients); odds ratio (OR), 0.65; 95% confidence interval (CI) 0.49–0.88; p = 0.005] and C-reactive protein (CRP) levels [5 studies (359 patients); mean difference (MD), −6.97; 95% CI −12.33 to −1.60; p = 0.01], but TSA revealed that the sample size needs to be larger. …”

Resistance to Systemic Inflammation and Multi Organ Damage after Global Ischemia/Reperfusion in the Arctic Ground Squirrel by Lori K. Bogren (551001)

“…For both I/R models, body temperature (Tb) was kept at 36.5–37.5°C. After reperfusion, animals were monitored for seven days (CA) or 3 hrs (HS) then tissues and blood were collected for histopathology, clinical chemistries, and cytokine level analysis (HS only). …”

HO-1 deficiency leads to poor bacterial clearance <i>in vivo</i> and <i>in vitro</i>. by Satindra Gahlot (3615662)

“…Cultures were harvested after 24 hours and plated on Muller Hinton agar plates with 1:10, 1:100 and 1:1000 dilutions and CFU of MRSA was determined by counting next day. Data are means ±SD of 3 independent experiments. Statistical significance *p<0.001 a significant decrease compared to MRSA alone exposed cultures; and #p<0.001 a significant increase compared to MRSA +CoPP treated cultures. …”

Image2_Effectiveness of prophylactic antibacterial drugs for patients with liver cirrhosis and upper gastrointestinal bleeding: a systematic review and meta-analysis.TIFF by Zhuo Wang (18668)

“…Summing up the relevant data, the dichotomous variable was statistically analysed using the relative risk (RR) value and its 95% confidence interval (CI) and the continuous variable using the mean difference (MD) value and its 95% CI. All analyses were performed using Revman 5.4 software. …”

Theoretical model of the transcription cycle and experimental setup. by Jonathan Liu (769699)

“…Because elongation continues after initiation has ceased, the 5’ MS2 signal begins decreasing before the 3’ PP7 signal. …”

DataSheet1_Effectiveness and mechanism of metformin in animal models of pulmonary fibrosis: A preclinical systematic review and meta-analysis.docx by Xuanyu Wu (1799395)

“…</p><p>Results: A total of 19 studies involving 368 animals were included, with a mean risk of bias of 5.9. The meta-analysis showed that MET significantly suppressed the level of inflammation and degree of PF in the lung tissue of the PF animal model. …”

Image_9_Sphingosine-1-Phosphate and Its Signal Modulators Alleviate Psoriasis-Like Dermatitis: Preclinical and Clinical Evidence and Possible Mechanisms.tif by Liu Liu (512237)

“…The pooled results showed that compared with control treatment, S1P receptor agonists [mean difference (MD): −6.80; 95% confidence interval (CI): −8.23 to −5.38; p<0.00001], and sphingosine kinase 2 inhibitors (MD: −0.95; 95% CI: −1.26 to −0.65; p<0.00001) alleviated psoriasis-like dermatitis in mice. …”

Image_13_Sphingosine-1-Phosphate and Its Signal Modulators Alleviate Psoriasis-Like Dermatitis: Preclinical and Clinical Evidence and Possible Mechanisms.tif by Liu Liu (512237)

“…The pooled results showed that compared with control treatment, S1P receptor agonists [mean difference (MD): −6.80; 95% confidence interval (CI): −8.23 to −5.38; p<0.00001], and sphingosine kinase 2 inhibitors (MD: −0.95; 95% CI: −1.26 to −0.65; p<0.00001) alleviated psoriasis-like dermatitis in mice. …”

DataSheet_1_Effects of hypoxia-inducible factor-prolyl hydroxylase inhibitors vs. erythropoiesis-stimulating agents on iron metabolism in non-dialysis-dependent anemic patients wit... by Junlan Yang (494886)

“…Among them, desidustat demonstrated the highest probability of increasing Hb (95.6%). Hepcidin [mean deviation (MD) = -43.42, 95%CI: -47.08 to -39.76], ferritin (MD= -48.56, 95%CI: -55.21 to -41.96), and transferrin saturation (MD = -4.73, 95%CI: -5.52 to -3.94) were decreased, while transferrin (MD = 0.09, 95%CI: 0.01 to 0.18) and total iron-binding capacity (MD = 6.34, 95%CI: 5.71 to 6.96) was increased in HIF-PHIs versus those in ESAs. …”

DataSheet_1_Metataxonomic and Metabolic Impact of Fecal Microbiota Transplantation From Patients With Pancreatic Cancer Into Germ-Free Mice: A Pilot Study.docx by Laurence Genton (9989290)

“…</p>Methods<p>We transplanted the feces from five PC patients and five age- and gender-matched healthy volunteers into two GF mice each. …”

Network evolution in the presence of oscillating hub. by Samuel Goldman (1699888)

“…</b> 10 different simulations with <i>N</i> = 500, <i>γ</i> = 1.9, show that the network can learn a maximum of 7 different target functions associated with 7 input frequencies before a loss in performance. To decrease variance emerging from trial-to-trial variability, behavior is averaged over 30 trials for 1–3 targets, 20 trials for 4–5 targets, and 10 trials for 6–7 targets. …”

Table_2_Intranasal Ketamine for Depression in Adults: A Systematic Review and Meta-Analysis of Randomized, Double-Blind, Placebo-Controlled Trials.DOCX by Dongjiao An (10904472)

“…The weighted mean difference of MADRS score was observed to decrease by 6.16 (95% CI 4.44–7.88) in 2–4 h, 9.96 (95% CI 8.97–10.95) in 24 h, and 4.09 (95% CI 2.18–6.00) in 28 day. …”

Trends in Respiratory Syncytial Virus and Bronchiolitis Hospitalization Rates in High-Risk Infants in a United States Nationally Representative Database, 1997–2012 by Abigail Doucette (2601559)

“…UB rates increased in all high-risk groups except for a 22.5% decrease among higher-risk CHD. Among high-risk infants, mechanical ventilation increased through 2012 to 20.4% and 13.5% of RSV and UB hospitalizations; geometric mean cost increased to $31,742 and $25,962, respectively, and RSV mortality declined to 0.9%.…”

Image_8_Sphingosine-1-Phosphate and Its Signal Modulators Alleviate Psoriasis-Like Dermatitis: Preclinical and Clinical Evidence and Possible Mechanisms.tif by Liu Liu (512237)

“…The pooled results showed that compared with control treatment, S1P receptor agonists [mean difference (MD): −6.80; 95% confidence interval (CI): −8.23 to −5.38; p<0.00001], and sphingosine kinase 2 inhibitors (MD: −0.95; 95% CI: −1.26 to −0.65; p<0.00001) alleviated psoriasis-like dermatitis in mice. …”

Table_1_Sphingosine-1-Phosphate and Its Signal Modulators Alleviate Psoriasis-Like Dermatitis: Preclinical and Clinical Evidence and Possible Mechanisms.docx by Liu Liu (512237)

“…The pooled results showed that compared with control treatment, S1P receptor agonists [mean difference (MD): −6.80; 95% confidence interval (CI): −8.23 to −5.38; p<0.00001], and sphingosine kinase 2 inhibitors (MD: −0.95; 95% CI: −1.26 to −0.65; p<0.00001) alleviated psoriasis-like dermatitis in mice. …”

An open-label, multiple ascending dose study of the anti-CTLA-4 antibody ipilimumab in viremic HIV patients by Elizabeth Colston (3998495)

“…Fourteen participants (58.3%) had an increase from baseline HIV-1 RNA (mean, 0.87 log₁₀ copies/mL; range, 0.59–1.29). …”

Histological and immunomorphological analysis of post-natal eye growth. by Olivier Cases (760028)

“…<p>Significantly increased axial length is first observed at P5 (<b>A</b>). The retinal lamination in P90 <i>Lrp2</i><sup><i>FoxG1</i>.…”

Data_Sheet_1_Surgery for Primary Cardiac Tumors in Children: Successful Management of Large Fibromas.docx by Tao Qian (1480588)

“…The fibroma volume index was negatively correlated with age (P = 0.039), with a mean value of 105 ± 70 ml/m². Of the 15 patients with fibromas, 5 were asymptomatic, 4 received partial resection, 4 required transmural resection, and 4 presented postoperative left ventricular (LV) dysfunction (ejection fraction <50%). …”

Image_2_Surgery for Primary Cardiac Tumors in Children: Successful Management of Large Fibromas.TIF by Tao Qian (1480588)

“…The fibroma volume index was negatively correlated with age (P = 0.039), with a mean value of 105 ± 70 ml/m². Of the 15 patients with fibromas, 5 were asymptomatic, 4 received partial resection, 4 required transmural resection, and 4 presented postoperative left ventricular (LV) dysfunction (ejection fraction <50%). …”

Image_3_Surgery for Primary Cardiac Tumors in Children: Successful Management of Large Fibromas.TIF by Tao Qian (1480588)

“…The fibroma volume index was negatively correlated with age (P = 0.039), with a mean value of 105 ± 70 ml/m². Of the 15 patients with fibromas, 5 were asymptomatic, 4 received partial resection, 4 required transmural resection, and 4 presented postoperative left ventricular (LV) dysfunction (ejection fraction <50%). …”