Glycosylated Platinum(IV) Complexes as Substrates for Glucose Transporters (GLUTs) and Organic Cation Transporters (OCTs) Exhibited Cancer Targeting and Human Serum Albumin Binding... by Jing Ma (24574)

“…Glycosylated platinum­(IV) complexes <b>5</b>, <b>6</b>, <b>7</b>, and <b>8</b> (IC₅₀ 0.24–3.97 μM) had better antitumor activity of nearly 166-fold higher than the positive controls cisplatin (<b>1a</b>), oxaliplatin (<b>3a</b>), and satraplatin (<b>5a</b>). …”

DataSheet_1_The bispecific B7H3xCD3 antibody CC-3 induces T cell immunity against bone and soft tissue sarcomas.docx by Samuel J. Holzmayer (18498150)

“…In turn, B7-H3 is considered a promising target for immunotherapeutic approaches. …”

Direct Membrane Deposition for CO₂ Electrolysis by Tartela Alkayyali (11432005)

“…The DMD approach provides flexibility to tune the properties of the composite and optimize the AEM:CEM ratio for low resistance and low H₂ evolution. Compared to a standard f-BPM, the DMD approach reduced the H₂ Faradaic efficiency by 2-fold (25% vs 12%, respectively), reduced mass transport resistance by over 50%, decreased full-cell potential by 0.84 V, increased the selectivity toward multicarbon products by over 2-fold (29% vs 65%, respectively), and achieved >17% in multicarbon product energy efficiency at 300 mA cm^–2.…”

DataSheet1_Influence of Martian Radiation-like Conditions on the Growth of Secale cereale and Lepidium sativum.pdf by N. Tack (11216079)

“…The dose can increase temporarily by a factor of 50 through the occurrence of highly energetic solar flares. …”

<i>HdhQ111</i>/+ mice exhibit an olfactory discrimination deficit. by Sabine M. Hölter (160170)

“…C-F: olfactory discrimination test. Mice were trained on a scent [S+] (either strawberry or apple) and then tested for their ability to recognize decreasing proportions of this scent in a binary mixture. …”

Table1_Co-Administration of Vonoprazan, Not Tegoprazan, Affects the Pharmacokinetics of Atorvastatin in Healthy Male Subjects.DOCX by Sejung Hwang (748233)

“…Safety was evaluated, including adverse events and clinical laboratory tests. A total of 28 subjects completed the study. When atorvastatin was co-administered with vonoprazan, the systemic exposures of atorvastatin and atorvastatin lactone significantly increased, and the metabolic ratio of 2-hydroxyatorvastatin significantly decreased. …”

Survival plot and comparison of neoplasm distribution between DR4 and F1 mice. by Silke H. Raffegerst (255365)

“…Results were subjected to statistical analysis using GraphPad Prism v5.0 software (GraphPad Software, San Diego California USA, <a href="http://www.graphpad.com" target="_blank">www.graphpad.com</a>). …”

Exemplar grasp-related channel. by David T. Bundy (7586414)

“…Spectral power changes were log transformed and z-scored relative to randomly selected time windows between trials, therefore, positive values indicated increases in spectral power, and negative values indicate decreases in spectral power. A broadband increase in spectral power in frequencies above 60Hz was observed for the pellet grasp. …”

Protease-sensitive PrP^Sc conformers in GSS P102L brain tissues. by Salvatore Monaco (47157)

“…(D) In case # 8, immunoblot with ICSM 35 did not reveal PrP^Sc after cPK treatment (lanes 7 and 8), wheras NaPTA precipitation showed a smear migrating in the upper part of the gel in a 50–70 kDa zone (lane 9, arrow), partially decreased by PNFase treatment (lane 10).…”

Data Sheet 1_Essential oil supplementation improves insulin sensitivity and modulates the plasma metabolome of hyperinsulinemic horses.zip by Caroline M. M. Loos (13181814)

“…Horses were blocked by degree of IS and assigned randomly to treatment: oral daily bolus (50 mL) of either a plant derived EO supplement or carrier (CON). …”

Constitutively active AMPK rescues Rheb-mediated axon guidance and phototaxis deficits, but not NMJ overgrowth or amplified EJP responses. by Brian Dimitroff (185260)

“…<p>(A–C) Expression of a constitutively activated <i>AMPK</i> transgene together with <i>Rheb⁺</i> greatly decreased the severity of the axon misrouting defects (arrows) normally seen in <i>Rheb</i>–overexpressing animals. …”

Quantifying crustal thickness and magmatic temperatures of the Jurassic to Early Cretaceous North-Andean arc by L. Chavarría (11713939)

“…Moderate rare earth elements (REE) slopes and depleted heavy REE patterns show that the primary residual magma source was amphibole, but plagioclase and pyroxene were also significant residual phases indicating that the magma source was formed in a crust that varied in thickness from 35 to 50 km. …”

Factors associated with treatment extended beyond 3-months. by James C. Coons (7943132)

“…Among the 66,573 OAC-treated patients who qualified based on having adequate enrollment after the index date, 33,439 (50.2%) had extended treatment for >6 months. Multivariable regression analysis revealed qualitatively similar results as observed among patients with treatment beyond 3 months, with the exception that the strength of association for decreased odds of extended treatment for Hispanic race patients (OR: 0.77 [0.71, 0.84]) compared with non-Hispanic white race, and patients with a Medicare Part D low-income subsidy (OR: 1.23 [1.12, 1.35]) was stronger compared with results from extended treatment beyond 3 months.…”

Data_Sheet_1_Altitudinal Distribution Patterns of Phyllosphere Microbial Communities and Their Contribution to Silage Fermentation of Kobresia pygmaea Along the Elevation Gradient... by Xin Yang (104842)

“…All K. pygmaea underwent a weak fermentation indicated by pH above 5.0 and low ratio of lactic/acetic acid (LA/AA). …”

Actual evapotranspiration and response factors of the cowpea in Amazonian edaphoclimatic conditions by Vandeilson B. Moura (12819832)

“…The experiment was carried out in randomized blocks, with six replicates and four treatments: T1 (100% ETc), T2 (50% ETc), T3 (25% ETc), and T4 (0% ETc), commencing in the reproductive phase with a drip irrigation system. …”

Dnmt1 exhibits similar binding affinities towards hemi- and non-methylated DNA. by Anna Schrader (817524)

“…<p><b>(A)</b> Scheme showing the setup of a microscale thermophoresis (MST) assay. …”

Positive Edge Effects on Forest-Interior Cryptogams in Clear-Cuts by Alexandro Caruso (195639)

“…We surveyed epixylic (dead wood inhabiting) forest-interior cryptogams (lichens, bryophytes, and fungi) associated with mature old-growth forests in 30 young managed Swedish boreal forest stands bordering a mature forest of high conservation value. In each young stand we registered species occurrences on coarse dead wood in transects 0–50 m from the border between stand types. …”

Hydrogel as mitigator of salt stress during the establishment of Tagetes patula L. seedlings by Naara I. G. Sousa (13219931)

“…The design used was randomized blocks in a split plot. The plots corresponded to seven levels of electrical conductivity of the irrigation water - ECw (0.5, 1.0, 2.0, 3.0, 4.0, 5.0, and 6.0 dS m-1) and the subplots corresponded to four hydrogel concentrations (0, 1.0, 2.0, and 3.0 g L-1), with five replicates and each subplot consisted of 27 seeds. …”

Narrative, Literature and the Experience of Illness, University of Pittsburgh by Post Discipline Admin (12858854)

Reversal of Obesity and Insulin Resistance by a Non-Peptidic Glucagon-Like Peptide-1 Receptor Agonist in Diet-Induced Obese Mice by Min He (44052)

“…Furthermore, circulating leptin, adiponectin, triglyceride, total cholesterol, nonesterified fatty acid and high-density lipoprotein/low-density lipoprotein ratio were normalized to various extents by Boc5 treatment.</p><h3>Conclusions/Significance</h3><p>Boc5 may produce metabolic benefits via multiple synergistic mechanisms and may represent an attractive tool for therapeutic intervention of obesity and diabetes, by means of non-peptidic GLP-1R agonism.…”