Tocopherol-human serum albumin nanoparticles enhance lapatinib delivery and overcome doxorubicin resistance in breast cancer by Milan Paul (12993859)

“…<p><b>Introduction:</b> HER2, a tyrosine kinase receptor, is amplified in HER2-positive breast cancer, driving cell signaling and growth. …”

Experimental and numerical study on year-round heat and mass transfer performance of an open counterflow heat-source tower heat pump system in high-humidity climates by Xinhao Liu (22512476)

“…Operational tests demonstrated that the system achieved COP ranging from 2.43 to 3.23 under typical January conditions and 3.8 to 5.0 under typical June conditions. The performance evaluation yielded a Heating Seasonal Performance Factor (HSPF) of 3.06, a Seasonal Energy Efficiency Ratio (SEER) of 4.3, and an Annual Performance Factor (APF) of 3.62. …”

Image1_Butyrate suppresses experimental necrotizing enterocolitis–induced brain injury in mice.tif by Maribel Martinez (485567)

“…Background<p>Necrotizing enterocolitis (NEC) is a devastating disease in premature infants, and 50% of infants with surgical NEC develop neurodevelopmental defects. …”

Paleocene to Miocene migmatization and kinematics of the deformation at the northern boundary of the Xolapa Complex: implications for the Chortís Block-southern Mexico connection by Alicia Sarmiento-Villagrana (3136950)

“…Our geochronological and structural data delineated an eastward decreasing age trend of migmatization, whereas the mylonitic deformation reported through the Xolapa Complex is consistent with a diachronous migration and detachment of the Chortís Block relative to the Acatlán Complex from Paleocene to early Miocene times.…”

Image2_Nitazoxanide, an Antiprotozoal Drug, Reduces Bone Loss in Ovariectomized Mice by Inhibition of RANKL-Induced Osteoclastogenesis.tif by Chang-hong Li (11816780)

“…The present study found that NTZ potently inhibited osteoclast formation at the early stage of receptor activator of NF-κB ligand-induced osteoclastogenesis in a concentration-dependent manner at a non-growth inhibitory concentration. …”

Supplemental data from: Extracellular Na+ and Orai1 contribute to endothelial wound healing by Ningyong Xu (6330494)

“…We found that PAEC monolayers migrated into wound areas and achieved confluence within 24 hours post-scratch. There was a fast healing phase within 5 hours, followed by a slow-healing phase between 5 and 24 hours. …”

Biodiversity of the Deep-Sea Continental Margin Bordering the Gulf of Maine (NW Atlantic): Relationships among Sub-Regions and to Shelf Systems by Noreen E. Kelly (236920)

“…Non-parametric estimators of species richness suggest a minimum of 50% of the deep-sea species inventory remains to be discovered.…”

Exercise-linked skeletal irisin ameliorates diabetes-associated osteoporosis by inhibiting the oxidative damage-dependent miR-150-FNDC5/pyroptosis axis by Jyotirmaya Behera (11496551)

“…In the present study, we investigated the effect of EX on bone mass and mechanical quality using a diabetic mouse model. The T2DM mouse model was established by a high-fat diet (HFD) with two streptozotocin (STZ) injections (50 mg/kg/body weight) in C57BL/6 female mice. …”

Table1_Nitazoxanide, an Antiprotozoal Drug, Reduces Bone Loss in Ovariectomized Mice by Inhibition of RANKL-Induced Osteoclastogenesis.docx by Chang-hong Li (11816780)

“…The present study found that NTZ potently inhibited osteoclast formation at the early stage of receptor activator of NF-κB ligand-induced osteoclastogenesis in a concentration-dependent manner at a non-growth inhibitory concentration. …”

Table_1_Autoimmune Encephalitis in Late-Onset Seizures: When to Suspect and How to Treat.DOCX by Marie Süße (8919182)

“…A total of 225 patients aged ≥50 years with epileptic seizures were enrolled and underwent an MRI/CT scan, profiling of neural antibodies (AB) in serum and cerebrospinal fluid (CSF), and neuropsychological testing. …”

Decoding biomass recalcitrance: Dispersion of ionic liquid in aqueous solution and efficient extraction of lignans with microwave magnetic field by Yu Xia (8822)

“…The optimum hydrolysis conditions were 0.2 g of ionic liquid catalyst per 5.0 g of <i>S</i>. <i>chinensis</i> fruits, a microwave irradiation power of 600 W, and heating time of 12 min, which gave a yield of free-state biphenyl cyclooctene lignans of 4.12±0.37 mg g⁻¹. …”

Data Sheet 1_Epidemiological analysis of maternal hypertensive disorders of pregnancy.docx by Aijuan Yuan (21898538)

“…Analysis by age showed that maternal hypertensive disorders caused the highest DALYs among women aged 25–39 years and the lowest DALYs among those aged 50–54 years. There was a positive relationship between ASIR and SDI. …”

DataSheet_1_Fighting eimeriosis by using the anti-eimerial and anti-apoptotic properties of rhatany root extract.docx by Saleh Al-Quraishy (729945)

“…The production of apoptotic markers including Caspase-3 (68.89 ± 2.67 U/g) and Bax (159.05 ± 6.50 pg/ml) was significantly elevated while decreasing the anti-apoptotic marker of BCL2 (0.42 ± 0.07 pg/ml). …”

Table_1_SEPT6_TRIM33 Gene Fusion and Mutated TP53 Pathway Associate With Unfavorable Prognosis in Patients With B-Cell Lymphomas.docx by Haiying Fu (1285074)

“…These frequently mutated genes were significantly associated with negative “regulation of gene expression, epigenetic” and virus infections such as cytomegalovirus, Epstein-Barr virus, human immunodeficiency virus 1 infections. We detected five fusion genes in at least two patients with B-cell lymphoma, and among them, TCF7L2_WT1 gene fusion was most frequently detected in 30.4% of patients (24 of 79 cases). …”

Image_3_SEPT6_TRIM33 Gene Fusion and Mutated TP53 Pathway Associate With Unfavorable Prognosis in Patients With B-Cell Lymphomas.tif by Haiying Fu (1285074)

“…These frequently mutated genes were significantly associated with negative “regulation of gene expression, epigenetic” and virus infections such as cytomegalovirus, Epstein-Barr virus, human immunodeficiency virus 1 infections. We detected five fusion genes in at least two patients with B-cell lymphoma, and among them, TCF7L2_WT1 gene fusion was most frequently detected in 30.4% of patients (24 of 79 cases). …”

miR-22 directly targets <i>MECOM</i> mRNA to regulate monocyte/macrophage differentiation. by Chao Shen (520343)

“…Ectopic expression of miR-22 decreased while inhibition of miR-22 increased endogenous MECOM levels in HL-60 and THP1 cells. …”

Image_2_SEPT6_TRIM33 Gene Fusion and Mutated TP53 Pathway Associate With Unfavorable Prognosis in Patients With B-Cell Lymphomas.tif by Haiying Fu (1285074)

“…These frequently mutated genes were significantly associated with negative “regulation of gene expression, epigenetic” and virus infections such as cytomegalovirus, Epstein-Barr virus, human immunodeficiency virus 1 infections. We detected five fusion genes in at least two patients with B-cell lymphoma, and among them, TCF7L2_WT1 gene fusion was most frequently detected in 30.4% of patients (24 of 79 cases). …”

Image_1_SEPT6_TRIM33 Gene Fusion and Mutated TP53 Pathway Associate With Unfavorable Prognosis in Patients With B-Cell Lymphomas.tif by Haiying Fu (1285074)

“…These frequently mutated genes were significantly associated with negative “regulation of gene expression, epigenetic” and virus infections such as cytomegalovirus, Epstein-Barr virus, human immunodeficiency virus 1 infections. We detected five fusion genes in at least two patients with B-cell lymphoma, and among them, TCF7L2_WT1 gene fusion was most frequently detected in 30.4% of patients (24 of 79 cases). …”

Mathematical model describing nucleosomal occupancy. by Barbara Celona (216140)

“…<p>(A) Affinity model based on saturation of nucleosomal sites. …”

Data_Sheet_1_Photoreceptor Degeneration in Pro23His Transgenic Rats (Line 3) Involves Autophagic and Necroptotic Mechanisms.docx by Kiana Kakavand (9593654)

“…Electroretinogram analyses revealed significantly decreased rod photoreceptor (a-wave), bipolar cell (b-wave) and amacrine cell responses (oscillatory potentials) from P30 onward. …”