Functional E2F sites in the Kpnβ1 (−637 to −271) and Kpnα2 (−180 to −24) promoter regions contribute to high promoter activity in transformed and cancer cells. by Pauline J. van der Watt (339036)

“…<p>A. Mutation of the five putative E2F sites in the Kpnβ1 (−637 to +100) promoter was carried out by site-directed mutagenesis. …”

Glycemic and metabolic correction after implantation of insulin-secreting autologous hepatocytes. by Nelson K. F. Chen (87519)

“…(A) Mean fasting glycemia in early and late treatment phases were significantly lower in treated pigs (<i>p</i><0.0001 for both phases). …”

Supplementary Materials - Antitumor activity of new chemical compounds in triple negative mammary adenocarcinoma models by Maria V Giolito (8499600)

“…</div><div>SM5: Effect of the compounds (50 and 25 µM) on 4T1 cells viability. …”

Data Sheet 1_The inflammatory architecture reflects the effects of pharmacological and genetic interventions on resolution of TLR2-mediated inflammation.pdf by Clara Kramer (22449295)

“…</p>Discussion<p>Combined with previously published results in the same inflammation model, we find that a strong decrease or increase of the PI region negatively affects resolution of inflammation, whereas a moderate decrease of 30-50% is associated with in part strongly enhanced resolution of TLR2-mediated inflammation.…”

Table_3_Endothelial Nitric Oxide Production and Antioxidant Response in Breath-Hold Diving: Genetic Predisposition or Environment Related?.XLSX by Danilo Cialoni (5023028)

“…At T30, we found a significantly lower decrease of NOx in subjects with a higher diving experience, but no difference was detected between the swimming pool and Sea. …”

DataSheet3_Clinacanthus nutans extract lowers periodontal inflammation under high-glucose conditions via inhibiting NF-κB signaling pathway.zip by Saruda Thongyim (19372687)

“…Treatment of C. nutans extract significantly reduced the expression of these pro-inflammatory cytokines and chemokines. At a concentration of 50 μg/mL, it reduced the relative expression of IL6, IL8, and CXCL10 to 0.51 ± 0.09, 0.6 ± 0.19, and 0.09 ± 0.02, respectively, compared to the non-treatment control, accompanied by a decrease in secreted protein as measured by ELISA. …”

DataSheet2_Clinacanthus nutans extract lowers periodontal inflammation under high-glucose conditions via inhibiting NF-κB signaling pathway.zip by Saruda Thongyim (19372687)

“…Treatment of C. nutans extract significantly reduced the expression of these pro-inflammatory cytokines and chemokines. At a concentration of 50 μg/mL, it reduced the relative expression of IL6, IL8, and CXCL10 to 0.51 ± 0.09, 0.6 ± 0.19, and 0.09 ± 0.02, respectively, compared to the non-treatment control, accompanied by a decrease in secreted protein as measured by ELISA. …”

Nuclear import of Avian Sarcoma Virus integrase is facilitated by host cell factors-2 by Mark D Andrake (95479)

“…Digitonin permeabilized HeLa cells were either treated with buffer (PBS – top row), or with a 50 ug/ml antibody 3E9 against Impβ (bottom row)during the import reaction. . …”

DataSheet4_Clinacanthus nutans extract lowers periodontal inflammation under high-glucose conditions via inhibiting NF-κB signaling pathway.zip by Saruda Thongyim (19372687)

“…Treatment of C. nutans extract significantly reduced the expression of these pro-inflammatory cytokines and chemokines. At a concentration of 50 μg/mL, it reduced the relative expression of IL6, IL8, and CXCL10 to 0.51 ± 0.09, 0.6 ± 0.19, and 0.09 ± 0.02, respectively, compared to the non-treatment control, accompanied by a decrease in secreted protein as measured by ELISA. …”

Table_1_Endothelial Nitric Oxide Production and Antioxidant Response in Breath-Hold Diving: Genetic Predisposition or Environment Related?.DOCX by Danilo Cialoni (5023028)

“…At T30, we found a significantly lower decrease of NOx in subjects with a higher diving experience, but no difference was detected between the swimming pool and Sea. …”

DataSheet1_Clinacanthus nutans extract lowers periodontal inflammation under high-glucose conditions via inhibiting NF-κB signaling pathway.pdf by Saruda Thongyim (19372687)

“…Treatment of C. nutans extract significantly reduced the expression of these pro-inflammatory cytokines and chemokines. At a concentration of 50 μg/mL, it reduced the relative expression of IL6, IL8, and CXCL10 to 0.51 ± 0.09, 0.6 ± 0.19, and 0.09 ± 0.02, respectively, compared to the non-treatment control, accompanied by a decrease in secreted protein as measured by ELISA. …”

Table_2_Endothelial Nitric Oxide Production and Antioxidant Response in Breath-Hold Diving: Genetic Predisposition or Environment Related?.DOCX by Danilo Cialoni (5023028)

“…At T30, we found a significantly lower decrease of NOx in subjects with a higher diving experience, but no difference was detected between the swimming pool and Sea. …”

<i>Apoe</i> expression is reduced in the parietal cortex and CA1 of aged mice. by Ileana Soto (531878)

“…(B) Quantification of <i>Apoe</i> hybridized area in the cortex shows a significant decrease of <i>Apoe</i> expression in the aged mice. …”

High Risks of Losing Genetic Diversity in an Endemic Mauritian Gecko: Implications for Conservation by Steeves Buckland (556786)

“…Simulations suggested that the chance of survival and allelic diversity of some subpopulations will decrease dramatically over the next 50 years if no migration occurs. …”

Impact of Protein Stability, Cellular Localization, and Abundance on Proteomic Detection of Tumor-Derived Proteins in Plasma by Qiaojun Fang (211668)

“…Quantitative comparison of large versus small tumors revealed that the abundance of proteins in plasma as measured by spectral count was associated with the tumor size, but the relationship was not one-to-one; a 3-fold decrease in tumor size resulted in a 16-fold decrease in protein abundance in plasma. …”

A53T homozygote mice develop gross motor abnormalities with age. by Katrina L. Paumier (440683)

“…Graphs are representative of data collected from 2–3 independent cohorts of animals with 8–15 mice per group. Data plotted as Mean+/− SEM. Bonferonni post hoc test *p<0.05, **p<0.001; s = seconds, cm = centimeters, M = month, WT = wild type, HO = homozygous.…”

Increasing risk of invasive adenocarcinoma of the uterine cervix in Cali, Colombia by Luis Eduardo Bravo (652275)

“…</p> <p>CONCLUSION: A significant increase in the incidence of cervical adenocarcinomas in women younger than 50 years was observed. …”

Voluntary Exercise Prevents Cisplatin-Induced Muscle Wasting during Chemotherapy in Mice by Pernille Hojman (61813)

“…<div><p>Loss of muscle mass related to anti-cancer therapy is a major concern in cancer patients, being associated with important clinical endpoints including survival, treatment toxicity and patient-related outcomes. …”

Table_1_Relationship between triglyceride-glucose index and cognitive function among community-dwelling older adults: a population-based cohort study.docx by Weimin Bai (7005770)

“…</p>Results<p>The study included 2,959 participants, with a mean age of 71.2 ± 5.4 years, 49.8% of whom were female. …”

Laparoscopic appendicectomy without the use of disposable materials - a low-cost alternative - 1,552 cases operated in 20 years by CARLOS EDUARDO DOMENE (5669693)

“…Methods: we applied three punctures - an umbilical one for the camera (5 or 10mm in diameter), a 10mm puncture in the right iliac fossa, and one 5mm puncture in the left iliac fossa. …”