Real-world Evidence of Efficacy and Safety of Sodium–Glucose Cotransporter 2 Inhibitors as Adjunctive Therapy in Adults With Type 1 Diabetes: A European Two-Center Experience by Ana Palanca (796358)

“…</p> <p><b>Results:</b> Overall, significant reductions in HbA1c (-0.5%), weight (-2.9 kg), and mean daily insulin (-8.5%) were achieved after 12 months. …”

Pol II occupancy is reduced at genes affected by P-TEFb depletion. by Olle Dahlberg (645665)

“…(<b>B</b>) Western blot with extracts from 0–5h old embryos show a decrease in Ser2-P in embryos depleted of maternal Cdk9 or CycT. …”

Radiation induces early alterations in NMDAR phosphorylation and internalization of NR1 and NR2A subunits. by Peter H. Wu (321655)

“…Surface receptors were separated by pull down with neutravidin beads and resolved by western blot. (NR1, 24.5±4.8% decrease in surface, NR2A, 23.4±5.9%, *p = 0.01 and 0.03 respectively, n = 10; NR2B 7.1±9.6%, GluR1 4.9±8.7%, p>0.25, n = 10; GluR2/3 2.97±8.8%, p = 0.89, n = 5).…”

Photo(chemo)therapy Reduces Circulating Th17 Cells and Restores Circulating Regulatory T Cells in Psoriasis by Takuya Furuhashi (276955)

“…Treg levels prior to treatment with Th17 high decreased group (5.16±2.20%) was significantly higher than that with Th17 high increased group (3.33±1.39%).…”

End-point variability and smallest effective ISS. by James P. Herman (304807)

“…The smallest effective ISS is the minimum ISS size for which a particular subject showed a significant adaptive decrease in gain (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0059731#pone-0059731-g002" target="_blank">Figure 2A</a>). …”

<i>In vivo</i> antileishmanial action of edelfosine in <i>L. panamensis- and L. braziliensis</i>-infected hamsters. by Rubén E. Varela-M (326741)

Changes in digestive enzymes activities during the initial ontogeny of wolf cichlid, Parachromis dovii (Perciformes: Cichlidae) by Carlos Alfonso Frías-Quintana (6675845)

Effect of <i>Nat10</i> on ribosome assembly. by Masato Taoka (189054)

“…Ribosomal and polysomal fractions prepared from strain SP6 (upper panel) or Nat10_G285D mutant (lower panel), grown at 30°C in YE medium were analyzed with 15–50% sucrose density gradient centrifugation. The UV profiles (A₂₅₄) of the separation are depicted. …”

Loss of mesenchymal <i>Srg3</i> disrupted BMP signaling and caused defective chondrogenesis in forelimb buds. by Shin Jeon (2559289)

Renal adaptations in hypertension preserve K+ while minimizing Na+ retention during pregnancy. by Melissa Stadt (17964875)

Mapping of mAb neutralizing activity. by Tysheena P. Charles (3385586)

“…(<b>G)</b> The log10 fold increase or decrease in IC₅₀ titer of each mutant PV relative to the parental BG505 PV is shown. …”

Patient baseline characteristics. by Josep Darbà (6428639)

EFFECTS OF AEROBIC EXERCISE ON BODY MORPHOLOGY IN OBESE UNIVERSITY STUDENTS by Ma Jin (12651607)

Reactive microsphere motion illustrates the discrete nature of bond formation events and force loading. by Brian J. Schmidt (255745)

“…An increase in the magnitude of the fluctuations of V_S,X was observed with the decrease in stiffness relative to (A). (C) Results for a 10 µm-diameter sphere with a freely-jointed chain model of force deformation, (6). …”

Contribution of core Atgs to autophagy of GFP-Snc1-PEM. by Zhanna Lipatova (771232)

“…Bar graph shows % of UPR compared to WT (100%); error bars, STD. Like in <i>atg11Δ</i> mutant cells, UPR is induced in <i>atg5Δ</i> and <i>atg7Δ</i> mutant cells (~6.5-fold). …”

Human complement inhibitors worsen GAS AP1 infection. by David Ermert (154423)

“…BALB/c (n = 7), hu-C4BP tg (n = 9), hu-FH tg (n = 8) and hu-C4BPxFH tg (n = 7) mice were infected i.v. with 5x10⁶ CFU of GAS AP1. (<b>B</b>) At high-dose infection with strain AP1 GAS (5x10⁷ CFU/mouse i.v.), ~83% of wt mice (n = 12) survived for 8 days compared to 20% survival of C4BP (single) tg mice (n = 15). …”

Kupffer cell depletion affects oval cell differentiation on day 9 after PH. by Shuai Xiang (326486)

“…Arrows point to oval cells. (Data represent mean ± SD, n = 4–5. *indicates significant difference when compared to control group, <i>P</i><0.05).…”

Sialylation of Prion Protein Controls the Rate of Prion Amplification, the Cross-Species Barrier, the Ratio of PrP^Sc Glycoform and Prion Infectivity by Elizaveta Katorcha (628696)

Superior Hard but Quickly Reversible Si–O–Si Network Enables Scalable Fabrication of Transparent, Self-Healing, Robust, and Programmable Multifunctional Nanocomposite Coatings by Yi Hou (148620)

“…The highly cross-linked continuous network endows the coating with a hardness (<i>H</i> = 0.83 GPa) higher than those of most polymers (<i>H</i> < 0.3 GPa), while the uniformly dispersed micelles decrease the Young’s modulus (<i>E</i> = 5.89 GPa) to a value as low as that of common plastics, resulting in excellent hardness and flexibility, with an <i>H</i>/<i>E</i> of 14.1% and an elastic recovery rate (<i>W</i>_e) of 86.3%. …”

The effects of β₁-adrenoceptor stimulation on I_Kur and I_Kto,f. by Vladimir E. Bondarenko (411443)

“…Simulated currents are obtained by 4.5-s depolarizing pulses to between −80 and +50 mV (in 10-mV increment) from a holding potential of −90 mV. …”