TAL1 associates with the <i>FUBP1</i> promoter via the <i>GATA</i> element to activate <i>FUBP1</i> expression. by Marlene Steiner (6240392)

“…<p><b>(A)</b> Schematic presentation of the reporter constructs used for luciferase assays. 0.5 kb genomic sequence upstream of the <i>FUBP1</i> transcription start were cloned upstream of the luciferase cDNA (left panel). …”

Structured illumination microscopy can resolve different synaptic domains. by Patricia T. Yam (478888)

“…Graphs represent the mean ± s.e.m. (<b>F</b>,<b>G</b>) During depolarization of neurons with 50 mM KCl, the synaptic vesicle markers vGlut1 and synaptophysin become smaller and more numerous, and spread over larger area (brackets). …”

Reduced mitochondrial membrane potential (ΔΨ_m) in <i>DJ-1</i>−/− MEFs. by Emilie Giaime (316501)

“…<p>(<b>A, B</b>) Confocal microscopic analysis. (<b>A</b>) Representative confocal microscopic images of <i>DJ-1</i>−/− and +/+ MEFs after staining with TMRM (50 nM, red) and Mitotracker Green (200 nM) in the presence or absence of oligomycin (Olig, 1 µM) or FCCP (10 µM). …”

SrrAB upregulates H₂O₂ resistance during periods of high aeration and imparts protection to AcnA. by Ameya A. Mashruwala (2939871)

“…Kat activity was assessed in cell-free lysates generated from the WT (JMB1100) and Δ<i>srrAB</i> (JMB1467) strains cultured at a culture vessel headspace to liquid volume ratios (HVR) of 2.5 or 10. …”

RnaA and DsbA modulate capsule production and Loki susceptibility through BfmRS and in different clinical isolates. by Jinna Bai (5903300)

“…A representative gel (top) and quantification from n = 3 samples (bottom; means ± s.d. analyzed by one-way ANOVA with Šídák’s multiple comparisons test) are shown as in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1010928#ppat.1010928.g005" target="_blank">Fig 5B</a>. …”

Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism by Tzu-Yin Lee (4518055)

“…<i>atg5</i>^−/− platelets also exhibited a lower aggregation in response to agonists, and platelet-specific <i>atg5</i>^−/− mice exhibited delayed thrombus formation in mesenteric microvessles and decreased mortality rate due to pulmonary thrombosis. …”

Supplementary Material for: Predictors of Supratentorial Deep Intracerebral Hemorrhage Volume and Their Effect on Short-Term Mortality in Asians by Han M.H. (4161883)

Smn deficiency in SMA type I axon terminals <i>in</i><i>vivo.</i> by Benjamin Dombert (648183)

“…Acetylcholine receptors (AChR) and postsynaptic nuclei were visualized by ω-BTX and DAPI, respectively (scale bar: 5 µm). In (A) Smn deficiency is visible by highly reduced immunoreactive signals, as highlighted in the white box, whereas in (B) the number of Smn particles per NMJ is decreased in SMA type I motor endplates, as indicated by white arrowheads. …”

<i>In vitro</i> 6xHis-CBU0823 activity assays for ME (A), LDH (B) and MDH (C) function, including the influence of varied pH (D), and substituted cofactors (E and F). by Janine Hofmann (11273418)

“…<p>(A) ME activity was observed for 20 μg 6xHis-CBU0823 in the ME standard assay containing 3 mM malate, 5 mM NAD⁺, 1 mM MnCl₂. 28.8 μg 6xHis-oMLE and 6xHis-mock purification negative control had no activity. …”

2-AA down-regulates the transcription of many genes involved in the translational capacity of the cell. by Yok-Ai Que (70055)

“…Exogenously added 2-AA decreases polysomes levels. Ribosomal extracts from PA14 cells grown in the absence (left panel) or presence (right panel) of exogenously added 2-AA were separated in a 25% to 5% sucrose density gradient. …”

Lactate levels in conditioned medium from breast cell lines under normoxia and hypoxia. by Nicola J. Brown (380651)

“…In MDA-MB-436 cells the mean lactate levels decreased slightly from 38.5 µM to 34.5 µM per 1×10⁶ cells (-0.9 fold change), but was not statistically significant (p = 0.229). …”

Table_4_Comprehensive Genome-Wide Analysis of Thaumatin-Like Gene Family in Four Cotton Species and Functional Identification of GhTLP19 Involved in Regulating Tolerance to Vertici... by Zhanshuai Li (9539504)

“…GhTLP19 on chromosome At05 was selected as a candidate gene for further study. When GhTLP19 was silenced by virus-induced gene silencing (VIGS) in cotton, with the increase of malondialdehyde (MDA) content and the decrease of catalase (CAT) content, and as the increase of disease index (DI) and hyphae accumulation, the plants were more sensitive to drought and Verticillium dahliae. …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”

Table1_Airport pavement performance evaluation of pavement fog seal based on optimized test technology.DOCX by Ping Li (31981)

“…The skid resistance performance of the three fog seal materials decreased after treatment. The decrease in material C was more significant than in materials A and B. …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates by Jeffrey Y. W. Mak (10132069)

“…Phthalimide capping groups, including a saccharin analogue, decrease rotational freedom and provide hydrogen bond acceptor carbonyl/sulfonamide oxygens that increase inhibitor potency, liver microsome stability, solubility, and cell activity. …”

Image_4_Comprehensive Genome-Wide Analysis of Thaumatin-Like Gene Family in Four Cotton Species and Functional Identification of GhTLP19 Involved in Regulating Tolerance to Vertici... by Zhanshuai Li (9539504)

“…GhTLP19 on chromosome At05 was selected as a candidate gene for further study. When GhTLP19 was silenced by virus-induced gene silencing (VIGS) in cotton, with the increase of malondialdehyde (MDA) content and the decrease of catalase (CAT) content, and as the increase of disease index (DI) and hyphae accumulation, the plants were more sensitive to drought and Verticillium dahliae. …”

The Effect of Ligand Lipophilicity on the Nanoparticle Encapsulation of Pt(IV) Prodrugs by Timothy C. Johnstone (1312911)

“…As the platinum concentration was increased, there was an initial increase in encapsulation followed by a decrease due to macroscopic precipitation. Maximal loading occurred when the platinum complex was present at a 40% w/w ratio with respect to polymer during the nanoprecipitation step. …”

Genetic evaluation of growth in Polled Nellore via multi-trait models by Isabella Coutinho de Barros (5939096)

“…Unlikely, a decrease was observed from W205 to W365 for the maternal permanent environmental effect. …”

Image_2_Comprehensive Genome-Wide Analysis of Thaumatin-Like Gene Family in Four Cotton Species and Functional Identification of GhTLP19 Involved in Regulating Tolerance to Vertici... by Zhanshuai Li (9539504)

“…GhTLP19 on chromosome At05 was selected as a candidate gene for further study. When GhTLP19 was silenced by virus-induced gene silencing (VIGS) in cotton, with the increase of malondialdehyde (MDA) content and the decrease of catalase (CAT) content, and as the increase of disease index (DI) and hyphae accumulation, the plants were more sensitive to drought and Verticillium dahliae. …”