Showing 18,181 - 18,200 results of 46,434 for search '(( 5 ((wt decrease) OR (mean decrease)) ) OR ( 50 ((nn decrease) OR (a decrease)) ))', query time: 0.71s Refine Results
  1. 18181

    Identification of a Plasma Four-microRNA Panel as Potential Noninvasive Biomarker for Osteosarcoma by Feng Lian (703027)

    Published 2015
    “…These 4 miRNAs were markedly decreased in the plasma after operation. In addition, circulating miR-195-5p and miR-199a-3p were correlated with metastasis status, while miR-199a-3p and miR-320a were correlated with histological subtype.…”
  2. 18182

    The effect of planting density on ‘BRS Rubimel’ peach trained as a “Y-shaped” system by André Luiz Kulkamp de Souza (5912453)

    Published 2019
    “…It was concluded that the densification of orchards is feasible for peach trees of the ‘BRS Rubimel’ cultivar due to the increase in productivity, without decreasing the quality of the fruits, indicating a spacing of 0.75 cm between plants and two scaffolds in the “Y-shape” as ideal. …”
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    Data_Sheet_1_Variations in the SDN Loop of Class A Beta-Lactamases: A Study of the Molecular Mechanism of BlaC (Mycobacterium tuberculosis) to Alter the Stability and Catalytic Act... by Sourya Bhattacharya (8441028)

    Published 2021
    “…To understand the molecular reasoning behind the unavailability of such mutation in real life, we have used circular dichroism (CD) spectroscopy, differential scanning calorimetry (DSC), molecular dynamics (MD) simulation, and stability-based enzyme activity to compare the stability and dynamic behaviors of native and S130G/A mutant form of BlaC. A significant decrease in melting temperature (BlaC T<sub>M</sub> 60°C, S130A T<sub>M</sub> 50°C, and S130G T<sub>M</sub> 45°C), kinetic instability at higher temperature, and comparative dynamic instability correlate the fact that resistance to beta-lactam/beta-lactamase inhibitor combinations will likely not arise from the structural alteration of BlaC, therefore establishing confidence that this therapeutic modality can be potentially applied as a part of a successful treatment regimen against M. tuberculosis.…”
  9. 18189

    Data_Sheet_2_Variations in the SDN Loop of Class A Beta-Lactamases: A Study of the Molecular Mechanism of BlaC (Mycobacterium tuberculosis) to Alter the Stability and Catalytic Act... by Sourya Bhattacharya (8441028)

    Published 2021
    “…To understand the molecular reasoning behind the unavailability of such mutation in real life, we have used circular dichroism (CD) spectroscopy, differential scanning calorimetry (DSC), molecular dynamics (MD) simulation, and stability-based enzyme activity to compare the stability and dynamic behaviors of native and S130G/A mutant form of BlaC. A significant decrease in melting temperature (BlaC T<sub>M</sub> 60°C, S130A T<sub>M</sub> 50°C, and S130G T<sub>M</sub> 45°C), kinetic instability at higher temperature, and comparative dynamic instability correlate the fact that resistance to beta-lactam/beta-lactamase inhibitor combinations will likely not arise from the structural alteration of BlaC, therefore establishing confidence that this therapeutic modality can be potentially applied as a part of a successful treatment regimen against M. tuberculosis.…”
  10. 18190

    Reduced nanodomain segregation, signaling, and internalization of the palmitoylation-deficient GLP-1R C438A mutant. by Teresa Buenaventura (4768041)

    Published 2019
    “…(D) Dose responses for exendin-4-induced clustering, measured by HTRF in INS-1 832/3 GLP-1R<sup>−/−</sup> stably expressing wt or C438A SNAP-GLP-1R, expressed as AUC for each concentration tested after segmentation into indicated time windows, 4-parameter logistic fits of pooled data shown with E<sub>max</sub> and log EC<sub>50</sub> (vertical dotted lines), paired <i>t</i> tests comparing parameter estimates for <i>n</i> = 5 repeats. …”
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    Evaluation of whole wheat flour sourdough as a promising ingredient in short dough biscuits by Tuba ALIOĞLU (10464668)

    Published 2021
    “…The incorporation of WWF on dough formulation increased both G' and G” moduli, while the inclusion of WWF by sourdough fermentation caused a significant reduction. Spread ratio of the biscuits decreased as the WWF ratio in the formulation increased (p < 0.05). …”
  15. 18195

    Vps34 supports Treg maintenance in lymphoid and non-lymphoid tissues. by Erienne G. Norton (9612079)

    Published 2025
    “…GSEA enrichment plots showing increased cTreg signature (left; i.e., top 200 upregulated genes [log<sub>2</sub>FC > 0.5, FDR < 0.05] in cTregs versus eTregs) and decreased eTreg signature (right; i.e., top 200 upregulated genes [log<sub>2</sub>FC > 0.5, FDR < 0.05] in eTregs versus cTregs) in CD45.2<sup>+</sup> Tregs from <i>Foxp3</i><sup>Cre</sup><i>Pik3c3</i><sup>fl/fl</sup> mixed BM chimera mice compared to control mixed BM chimera mice. …”
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