Crystal structure and cytotoxic activities of a bis(pyrrolyl-imine) gold(III) complex by Daniel De Moraes Profirio (2885411)

“…Cytotoxic activity of [Au(pyren)]⁺ was active against three tumorigenic cell lines with IC₅₀ values of 35 μM. Interaction studies with CT-DNA by fluorescence and competition with ethidium bromide (EB) showed a quenching of the emission band of DNA with a Stern–Volmer quenching constant value of (3.0 ± 0.1) × 10⁴ M⁻¹ and a decrease in fluorescence quenching of EB-DNA system, respectively, confirming that DNA is a possible target for the complex via an intercalative binding, which was confirmed by DNA conformational changes observed with circular dichroism spectroscopy.…”

Higher expression and nonsense mutations of Fhod3 in the DBA/2J mice and generation of Fhod3 transgenic mouse. by Ely Cheikh Boussaty (17471493)

Adherence to medication before and after the use of a Drug-Dispensing System with usage control by Liliana Batista Vieira (5960912)

“…After the use of the system, 100% were considered as "more adherent" (p < 0.01), the means of the systolic blood pressure decreased 23.7 mmHg (p=0.000), the diastolic blood pressure decreased 12.1 mmHg (p=0.004) and glycemia diminished 79.3 mg/dl (p=0.000). …”

<i>S. aureus</i> RnpA catalyzes rRNA and mRNA digestion. by Patrick D. Olson (230450)

“…The band at ∼17.2 kDa (solid arrow; Band 2) was confirmed to be <i>S. aureus</i> RnpA by tandem mass spectrometry (Wistar Institute; Philadelphia, PA), whereas top-hits for minor contaminants (dashed arrows) were determined to be <i>E. coli</i> 50S ribosomal protein L3 (Band 1) or <i>S. aureus</i> RnpA polypeptide fragments, corresponding to amino acids 11–107 (Bands 3 and 4) or 12–107 (Band 5). …”

A small proportion of Talin molecules at muscle attachment sites in vivo are mechanically engaged. by Sandra B. Lemke (6519788)

“…(D) Talin forces measured by FLIM-FRET using the HP-sensor module (6–8 pN). A decrease in FRET efficiency of Talin-TS compared to the C-terminal zero-force control (C-TS) indicates force. …”

Data_Sheet_1_The Effect of 42-Day Exposure to a Low Deoxynivalenol Dose on the Immunohistochemical Expression of Intestinal ERs and the Activation of CYP1A1 and GSTP1 Genes in the... by Magdalena Gajęcka (11151711)

Potency of CCh (pD₂) and Atropine (pA₂) on the ileum (a, b, c) and on the colon (d, e, f) from mice with chronic colitis. by Rita Aldini (92787)

“…After induction of chronic colitis, Charbacol pEC₅₀ decreased by 8.71 times in the ileum and 2.34 times in the colon and Atropine p<i>A</i>₂ was increased by 1.35 and 3.09 times in the ileum and the colon respectively, compared with the corresponding intestinal segments of control mice. …”

Effect of regulation and NGAM on lifespan. by Barbara Schnitzer (6246920)

The association between previous and future severe exacerbations of chronic obstructive pulmonary disease: Updating the literature using robust statistical methodology by Mohsen Sadatsafavi (63962)

“…Even after adjusting for observable characteristics, individuals in the 97.5th percentile of exacerbation rate had 5.6 times higher rate of severe exacerbations than those in the 2.5th percentile.…”

Table 1_Obinutuzumab in systemic lupus erythematosus: a real-world experience.docx by Chunmei Wu (3202050)

“…Mean SLEDAI-2K decreased from 11.75 ± 9.31 (range: 0 to 46) to 1.45± 1.93 (range: 0 to 8). …”

Enhancement of biological effectiveness of carbon-ion beams by applying a longitudinal magnetic field by Taku Inaniwa (6239012)

“…</p> <p><b>Methods and materials:</b> Human cancer and normal cell lines were exposed to low (12 keV/<i>μ</i>m) and high (50 keV/<i>μ</i>m) linear energy transfer (LET) carbon-ion beams under the longitudinal magnetic fields of <i>B</i>_// = 0, 0.1, 0.2, 0.3, or 0.6 T generated by a solenoid magnet. …”

Gingival recession treatment with concentrated growth factor membrane: a comparative clinical trial by Serap Karakış AKCAN (8650455)

“…A statistically significant decrease was observed in CAL, RD, and RW, and KTT increased in all groups at three and six months compared with the baseline. …”

(A) Evidence and types of selection: (Top) Schematic of the lowest mean value fractional rank value (λ) distributions for local heterozygosity in a sample of 45 European Americans... by Taras K. Oleksyk (53041)

Fig 7 - by Michael T. Williams (357796)

Immunofluorescent staining of TMEM43 and IC disc proteins in HL-1 cells stably expressing wild-type and mutant TMEM43. by Vinayakumar Siragam (455948)

Targeted quantitation in aging worms and in an azyx-1a deletion mutant reveals age-dependent zyx-1 fold change and <i>cis</i> regulation by azyx-1. by Bhavesh S. Parmar (11603824)

Influence of Solubilizing Group Removal Rate on the Morphology and Crystallinity of a Diketopyrrolopyrrole-Based Compound by Shabi Thankaraj Salammal (1864396)

“…This means that, when the heating rate is decreased from 50 to 0.1 °C/min, the crystallinity of DPP-4T powder decreases from 49% to 34%, and the grain size of DPP-4T film reduces from 976 to 344 nm. …”

Influence of Solubilizing Group Removal Rate on the Morphology and Crystallinity of a Diketopyrrolopyrrole-Based Compound by Shabi Thankaraj Salammal (1864396)

“…This means that, when the heating rate is decreased from 50 to 0.1 °C/min, the crystallinity of DPP-4T powder decreases from 49% to 34%, and the grain size of DPP-4T film reduces from 976 to 344 nm. …”

Plots of gene expression values for <i>SOX5</i>, <i>COL2A1</i>, <i>ELN</i>, <i>B2M</i>, <i>CASP8</i>, <i>CASP9</i>, and <i>IL1A</i> normalized to large ribosomal fraction, <i>P0</i... by Narihiko Hirano (11104945)

“…Error bars represent standard error of the mean for normalized gene expression values. <i>SOX6</i> or <i>SOX9</i> = SRY (sex determining region Y)-box 6 or 9.…”

Data Sheet 1_Chinese patent medicine tongxinluo capsule as a supplement to treat chronic coronary syndromes: a GRADE-assessed systematic review and meta-analysis of randomized cont... by Shi-Bing Liang (10200806)

“…Evidence supports the use of TXL plus WM for reducing angina frequency [SMD −2.50, 95% CI (−3.53, −1.48)], improving seattle angina questionnaire scores (P < 0.05), decreasing nitroglycerin dose [SMD −1.63, 95% CI (−2.26, −1.00)], and shortening angina duration [MD −1.50 min/once, 95% CI (−1.98, −1.02)]. …”