αIIbβ3-deficient platelets fail to spread, form thrombi, or efficiently secrete granule contents over immobilized IgG. by Huiying Zhi (706852)

“…Representative images of three independent experiments are shown. Scale bar, 5 μm. Note that αIIbβ3-deficient platelets failed to spread on fibrinogen, as expected, but also failed to spread on immobilized IgG. …”

Effects of Meloxicam on the Welfare of Holstein Calves from 6 Weeks to 6 Months Old Undergoing Amputation Dehorning by Jiancheng Qi (17878619)

“…The first group (Placebo) received <a href="" target="_blank">a subcutaneous injection of 5 ml of lidocaine in the horn area and a subcutaneous injection of 0.9% </a>saline at a dose of 0.025 mL/kg in the neck, administered 10 minutes before the AD procedure. …”

Treatment with a fecal microbiota transplant following spinal cord injury reduced anxiety-like behaviour. by Emma K. A. Schmidt (8307642)

“…Sham = 19.42% ± 9.91, SCI = 9.5% ± 9.58, SCI-FMT = 19.71% ± 11.79, Healthy = 22.94% ± 8.67). …”

Differential regulation of transcriptional and metabolic profiles in DN-POLG cells in the course of inducible mtDNA depletion. by Oswaldo A. Lozoya (766244)

“…Transcriptional profiling was based on DEGs identified using log2-transformed fold-changes in RPKM versus the mean at day 0 (Log2FC) in two-way ANOVA tests (gene × time) at an adjusted Benjamini-Hochberg <i>p</i> ≤ 0.05. …”

Efficacy of astragalus combined with renin-angiotensin-aldosterone system blockers in the treatment of stage III diabetic nephropathy: a systematic review and meta-analysis by Yu-qiong Lin (18768653)

“…Astragalus combined with RAAS blockers yielded a significantly higher total effective rate (TER) (mean difference [MD] 3.63, 95% confidence interval [CI] 2.59–5.09) and significantly reduced urinary protein excretion rate (UPER), serum creatinine (Scr), blood urine nitrogen (BUN) and glycosylated hemoglobin (HbAlc) levels. …”

FIGURE 4 from D-2-HG Inhibits <i>IDH1^mut</i> Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation by Sean T. Pianka (18237413)

“…Growth inhibition following FTO inhibitor treatment (FB23-2 = 3 µmol/L; MA = 100 µmol/L) in <i>IDH1^wt</i> HK217 (<b>E</b>) and HK250 (<b>F</b>) gliomaspheres. …”

Parameters used for the simulation of the model^a. by Balázs Könnyű (349622)

“…The pH within virions is unclear; however, it may be assumed to be close to the optimum for PR activity (pH∼5.5), we have therefore selected parameter estimates obtained at this pH wherever available.…”

Effect of temporal control of the Raf/MEK/ERK pathway on PC12 neurite outgrowth. by Kai Zhang (102844)

“…Data are presented by mean ± standard error (s.e.m.).</p>…”

Predicted fitness and predicted prevalence. by Taj Azarian (659326)

“…Two outliers are annotated for which the difference between their predicted and observed prevalence was >1.5 times the interquartile range of the distribution of predicted and observed prevalence differences. …”

The susceptibility of <i>Y. enterocolitica</i> O:9 strains with and without protein OmpX to normal human serum. by Karolina Skorek (487088)

“…<p>Strains Ye9 (wt) and Ye13 (Ye9 OmpX⁻) were grown to exponential phase at 37°C and incubated with 50% NHS at 37°C. Aliquots removed at 0, 15, 30 and 60 min were plated for viability counts (CFU). …”

Effects of sitagliptin on proliferation and migration of rat aortic smooth muscle cells (RAoSMC). by Soo Lim (172772)

“…<p>A. In MTT viability assays, cell proliferation was significantly decreased by sitagliptin treatment (*p < 0.05 compared with PDGF-BB only). …”

YK-4-279 inhibits ERG and ETV1 transcriptional activity. by Said Rahim (222786)

“…Id-2 promoter activity was decreased upon YK-4-279 treatment without affecting ERG protein levels. * ; p<0.001. c) VCaP cells were treated with 50 nM siERG or 10 µM YK-4-279 for 48 hours and mRNA and protein expression levels of ERG targets were evaluated. …”

MMV291 analogues interfere with actin polymerisation in the presence of profilin in vitro. by Madeline G. Dans (14193815)

“…<b>(B)</b> Upon addition of PfPFN, actin sedimentation decreased to 21 ± 1% with DMSO treatment. All MMV291 analogues, <i>S</i>-MMV291, <i>R</i>-MMV291, <i>S</i>-W936, <i>R</i>-W936, <i>S</i>-W414, and <i>S</i>-W827, decreased the amount of actin in the pellet further to 11 ± 1%, 15 ± 2%, 8 ± 2%, 10 ± 4%, 9 ± 4%, and 5 ± 2%, respectively. …”

Neutrophil motility in healthy donors. by Kathryn L. Butler (244702)

“…<p><b>a</b>. Average neutrophil motility in 18 healthy donors. …”

Large inputs exhibiting PPD produce synchronized, low-pass responses. by Cal F. Rabang (191595)

“…<p><i>A,</i> Spike rate curves from simulations using 2 Large inputs with 1 ms jitter. …”

S-nitrosylation pattern during <i>Trypanosoma cruzi</i> trypomastigotes adhesion to extracellular matrix. by Milton Pereira (719447)

“…The Ponceau’s staining was used as a load control. Arrows indicate protein bands in which the signal intensity is decreased on the group incubated with the extracellular matrix in relation to the equivalent group incubated with growth media alone. …”

The selection of optimal inductive strategy for FLSPCs. by Wei-hui Liu (211269)

“…<p>(A) Following induction for 14 days, the expression of AFP sequentially decreases in the four groups. …”

Bioassay-Guided Isolation of Fungistatic by MARCELO SILVA (21417932)

“…<p dir="ltr">The study of a leaf extract from Mimosa caesalpiniifolia that fights fungi discovered 28 compounds, including new ones like 6-(β-boivinopyranosyl)apigenin (1), 8-(β-oliopyranosyl)apigenin (2), and (E)-6-(2-carboxyethenyl)apigenin (3). …”

Effects of DIDS on forskolin-induced I_SC in the absence and presence of Uzara or ouabain. by Jörg D. Schulzke (354049)

“…Application of 10 µM forskolin induced an I_SC that was reduced in the presence of Uzara (50 µg/ml) and ouabain (100 µM). Under all three conditions, application of DIDS (100 µ µM) caused a pronounced transient increase in I_SC, presumably due to an increase in intracellular Ca²⁺. …”

Immunocytochemical analyses of cultured Müller cells in medium with G5 by Theodorus L. Ponsioen (89473)