Quercetin Loaded Silica and Gold - Coated Silica Nanoparticles: Characterization, Evaluation and Comparison of Their in vitro Characteristics by Areen M., Khattabi

“…The drug was encapsulated in silica NPs in a high percentage (71%) and reduced by about 16% after gold coating. The mean particle size increased after coating and QC loading with a polydispersity index (PDI) between (∼ 0.2 - 0.6) and negative zeta potential (-13 to - 15 mV). …”
Get full text
Get full text
Get full text

Igf signaling is required for proper cardiomyocyte number in zebrafish embryonic hearts. by Ying Huang (53474)

“…<i>myl7:nDsRed</i> embryos were treated with Igf1r inhibitor (D) (n = 20) and DMSO as a control (B) (n = 20) from 48 to 72 hpf and observed at 76 hpf. a: atrium, v: ventricle. Scale bar = 20 µm. (E, F) Quantification of mean ventricular cardiomyocyte number ± S.E. …”

Ranolazine (RAN) inhibited the increase in <i>I</i>_Na.L caused by 300 µM H₂O₂. by Chunping Qian (294424)

“…<p><i>A</i>. 3, 6 and 9 µM ranolazine decreased the amplitudes of the increased <i>I</i>_Na.L induced by 300 µM H₂O₂ in a concentration dependent manner. …”

Scribble is required for normal myelin initiation in vitro. by Andrew A. Jarjour (343100)

“…Numerical results are presented as mean ± SEM. ANOVA with Tukey's multiple comparison test was used; <i>n</i> = 6 coverslips per condition, five fields were analysed per coverslip. * <i>p</i> < 0.05 versus Mock. ** <i>p</i> < 0.01 versus Mock, *** <i>p</i> < 0.005 versus Mock. …”

Data Sheet 1_OvaRePred (HerTempo): an enhanced ovarian aging clock for personalized reserve assessment, endocrine age modeling, and predicting reproductive milestones across the fe... by Huiyu Xu (12255545)

“…A two-parameter logistic curve allowed translation of ovarian reserve scores into an “endocrine age” and enabled individualized prediction of future milestones, such as diminished reserve with ovarian score of 50 and perimenopause, the lowest ovarian reserve score in our ART population. …”

Gene activation and global RNA synthesis by NGF. by Yu-Wei Lee (432337)

“…<p>(<b>A</b>)PC12 cells were incubated with NGF (50 ng/ml) or without NGF for 4 hours. mRNA levels were measured using RT-qPCR relative to the house keeping gene <i>cyclophilin A</i> mRNA. …”

<i>ab</i> cooperates with impaired Hippo pathway signalling to drive tumour overgrowth. by Nezaket Turkel (434914)

“…F-actin for cell morphology is in red. GFP (panels A–H), Elav (panels A′–D′), Dac (panels E′F′), Eya (panels G′H′), and merges (panels A″–H″). …”

Image 4_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.tif by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

HAS inhibition in HepR21 leads to ROS surge, decline in HA level and upregulated MAP-LC3 levels. by Paramita Saha (473954)

“…<p>[A] <b><i>Inhibition of HA synthesis led to increased generation of ROS</i></b><b>—</b> HepR21 cells subjected to treatment with different concentrations of HA synthetase inhibitor, 4-MU and untreated cells were assayed for ROS. 4-MU treatment resulted in excess generation of ROS as a function of time and concentration. …”

Supplementary file 1_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.docx by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

DataSheet1_Reduce the application of phosphorus fertilizer in peanut fields and improve its efficiency by using iron modified biochar to adsorb phosphorus recovery products.docx by Junxiao Zhang (421908)

“…After the fifth desorption and recycling process, the adsorption capacity of the biochar decreased to 24%. The peanut yield in the FeB-P1 treatment was 50.8% higher than that in the FeBP-P2 treatment. …”

Table_1_Higher adherence to the Dietary Approaches to Stop Hypertension (DASH Diet) is associated with lower greenhouse gases and land use from protein foods.DOCX by Nicole R. Kling (16327404)

“…Diets with the greatest adherence had around 25–50% lower GHG and land use from total protein foods than diets with the lowest adherence. …”

Image 1_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.tif by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

Image_1_Gonadotropin-Releasing Hormone Receptor-Targeted Near-Infrared Fluorescence Probe for Specific Recognition and Localization of Peritoneal Metastases of Ovarian Cancer.JPEG by Qiyu Liu (3961796)

“…The fluorescence signal of peritoneal metastases peaked in intensity at 2 h and maintained for up to 48 h. ICG also showed a weak signal in the tumor lesions due to the enhanced permeability and retention effect, but the intensity decreased quickly within 48 h.…”

Image 2_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.tif by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

Galactose-1-phosphate uridyltransferase (GalT), an <i>in vivo</i>-induced antigen of <i>Actinobacillus pleuropneumoniae</i> serovar 5b strain L20, provided immunoprotection against... by Fei Zhang (85787)

“…Indirect enzyme-linked immunosorbent assay (ELISA) confirmed that GALT specific antibodies could not be induced by inactivated APP L20 or MS71 whole cell bacterin preparations. A recombinant fusion GALT protein derived from APP L20, however has proven to be an effective cross-protective antigen against APP sevorar 1 MS71 (50%, 4/8) and APP sevorar 5b L20 (75%, 6/8). …”

Image 3_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.tif by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

Image_5_Gonadotropin-Releasing Hormone Receptor-Targeted Near-Infrared Fluorescence Probe for Specific Recognition and Localization of Peritoneal Metastases of Ovarian Cancer.JPEG by Qiyu Liu (3961796)

“…The fluorescence signal of peritoneal metastases peaked in intensity at 2 h and maintained for up to 48 h. ICG also showed a weak signal in the tumor lesions due to the enhanced permeability and retention effect, but the intensity decreased quickly within 48 h.…”

Table_1_Soil CO2 and N2O emissions and microbial abundances altered by temperature rise and nitrogen addition in active-layer soils of permafrost peatland.DOCX by Yanyu Song (14249957)

“…An NH₄NO₃ solution was added to soil at a concentration of 50 mg N kg⁻¹ to investigate the effect of nitrogen addition. …”

Table_1_Protective Effect of Bruguiera gymnorrhiza (L.) Lam. Fruit on Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice: Role of Keap1/Nrf2 Pathway and Gut Microbiota.docx by Yinsi Lin (8392215)

“…Colitis was induced by oral intake of dextran sulfate sodium (DSS) and treated with aqueous extract of BGF (25, 50 and 100 mg/kg) for a week. The Disease Activity Index (DAI), colon length, and histological changes of colon were analyzed. …”