Atg14 does not contribute to terminal eTreg generation during perinatal life. by Erienne G. Norton (9612079)

DataSheet_1_A phase I trial of SON-1010, a tumor-targeted, interleukin-12-linked, albumin-binding cytokine, shows favorable pharmacokinetics, pharmacodynamics, and safety in health... by Richard T. Kenney (15289313)

“…Despite some signs of efficacy since then, most rIL-12 clinical trials have encountered hurdles such as short terminal elimination half-life (T_½), limited tumor microenvironment targeting, and substantial systemic toxicity. We developed a strategy to extend the rIL-12 T_½ that depends on binding albumin in vivo to target tumor tissue, using single-chain rIL-12 linked to a fully human albumin binding (F_HAB) domain (SON-1010). …”

Uvrag in Tregs is dispensable for establishment of immune tolerance and eTreg accumulation. by Erienne G. Norton (9612079)

Overidentification test results. by Pu Miao (12886949)

Table 1_Proton therapy achieves high-dose tumor control with organ preservation in complex metastatic adenoid cystic carcinoma: a case report of a refractory patient with 16 pulmon... by Zejun Lu (2279458)

“…This approach represents a viable strategy for complex cases where conventional radiotherapy is contraindicated. …”

Related to Fig 3. by Mohammad Nafees Ansari (22232505)

“…(<b>O</b>, <b>P</b>) Cell proliferation assay confirms an increase in cell proliferation of BT-474_ZFX^OE cells (mean ± SEM, <i>n</i> = 5) (O), whereas BT-474_ZFX^SL cells (mean ± SEM, <i>n</i> = 3) show decreased cell proliferation (P). …”

Related to Fig 1. by Mohammad Nafees Ansari (22232505)

“…(<b>J</b>–<b>M</b>) Immunoblot confirms silencing of UGCG in MCF-7 and BT-474 cells (J, L) and cell proliferation assay demonstrates a decrease in proliferation in MCF-7_UGCG^SL and BT-474_UGCG^SL cells over MCF-7_SCRAM^SL (mean ± SEM, <i>n</i> = 5) and BT-474_SCRAM^SL cells (mean ± SEM, <i>n</i> = 3) (K, M). …”

Prenatal medication use in a prospective pregnancy cohort by pre-pregnancy obesity status by Yassaman Vafai (10294851)

“…Since the study exclusion criteria limited the non-obese group to women without thyroid disease, in a sensitivity analysis we excluded all women who reported thyroid medication intake and still a higher proportion of women with obesity took the hormones and synthetic substitutes class compared to women without obesity.…”

Bone Morphogenetic Protein for the Healing of Tibial Fracture: A Meta-Analysis of Randomized Controlled Trials by Jiezhi Dai (500546)

“…The quality of the trial was assessed, and meta-analyses were performed with the Cochrane Collaboration’s REVMAN 5.0 software.</p><p>Results</p><p>Eight RCTs involving 1113 patients were included. …”

Effects of Coenzyme Q10 on Markers of Inflammation: A Systematic Review and Meta-Analysis by Junya Zhai (3710125)

Identification of a Plasma Four-microRNA Panel as Potential Noninvasive Biomarker for Osteosarcoma by Feng Lian (703027)

“…These 4 miRNAs were markedly decreased in the plasma after operation. In addition, circulating miR-195-5p and miR-199a-3p were correlated with metastasis status, while miR-199a-3p and miR-320a were correlated with histological subtype.…”

The effect of planting density on ‘BRS Rubimel’ peach trained as a “Y-shaped” system by André Luiz Kulkamp de Souza (5912453)

“…It was concluded that the densification of orchards is feasible for peach trees of the ‘BRS Rubimel’ cultivar due to the increase in productivity, without decreasing the quality of the fruits, indicating a spacing of 0.75 cm between plants and two scaffolds in the “Y-shape” as ideal. …”

MPA induced IRS2 and increased glucose metabolism in CAFs of obese women. by Intan Sofia Omar (10451088)

Fig 2 - by Tachpon Techarang (12295244)

Fig 2 - by Atikarn Janthongkaw (17020498)

P8, but not the p8m mutant peptide, represses KSHV lytic reactivation. by Shaowei Wang (490684)

Targeting of Vps34 or Atg14, but not Uvrag, in Tregs reduces tumor growth in mouse models. by Erienne G. Norton (9612079)

Reduced nanodomain segregation, signaling, and internalization of the palmitoylation-deficient GLP-1R C438A mutant. by Teresa Buenaventura (4768041)

“…(D) Dose responses for exendin-4-induced clustering, measured by HTRF in INS-1 832/3 GLP-1R^−/− stably expressing wt or C438A SNAP-GLP-1R, expressed as AUC for each concentration tested after segmentation into indicated time windows, 4-parameter logistic fits of pooled data shown with E_max and log EC₅₀ (vertical dotted lines), paired <i>t</i> tests comparing parameter estimates for <i>n</i> = 5 repeats. …”

Test apparatus. by Sara Hintze (3216885)

Evaluation of whole wheat flour sourdough as a promising ingredient in short dough biscuits by Tuba ALIOĞLU (10464668)

“…The incorporation of WWF on dough formulation increased both G' and G” moduli, while the inclusion of WWF by sourdough fermentation caused a significant reduction. Spread ratio of the biscuits decreased as the WWF ratio in the formulation increased (p < 0.05). …”