SCI alters the mRNA expression of canonical Wnt signalling components. by Carmen María Fernández-Martos (5649061)

“…<p>Expression of the canonical co-receptor <i>LRP5/6</i>, the downstream intracellular inhibitory transducer <i>GSK3-ß</i> and the <i>ß-catenin</i> transcription factor were quantified by qRT-PCR as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0027000#pone-0027000-g001" target="_blank">Figure1</a>. …”

Vsp1 associates with brain endothelium. by Gaurav Gandhi (239145)

“…Notice that Eu-LVsp1 associated with HBMEC in a time-dependent manner (panels A–C); also notice that the association of LVsp1 with HBMEC was saturable (panel A), did not occur with non-lipidated rVsp1 or albumin (panel B), and decreased by incubation at lower temperature (panel C).…”

Induction of experimental dry eye. by Susan R. Heimer (418710)

“…(A) EDE resulted in significant decreases in tear volume after 2 days. …”

There was no difference in AAR between the different groups by Matthias Götberg (43623)

“…(b) Infarct size (IS) measured by ex-vivo MRI as a percentage of area at risk (AAR) by SPECT in the two groups. …”

Accuracy of consumer-level and research-grade activity trackers in ambulatory settings in older adults by Salvatore Tedesco (6029417)

“…Gold-standards included treadmill, ECG-based chest strap, direct observation or video recording according to the activity and parameter. Every tracker showed a decreasing accuracy with slower walking speed, which resulted in a significant step under-counting. …”

Sizes and lifetimes of clathrin-coated structures forming at the cell surfaces. by Saveez Saffarian (249084)

“…The data derive from time series (100-ms exposures) of at least 15-min duration recorded every 5 s (full circles) or 60-min duration recorded every 10 s (empty circles) using a spinning disk confocal fluorescence microscope. …”

CUSPER-based demonstration of detachment and re-attachment of bacterial cells at the agarose-water interface. by Annemieke van der Wal (195948)

Wnt signalling in normal breast cell lines (N), ER-ve (T−) and ER+ve (T+) breast cancer cell lines. by Rebecca Lamb (105412)

Influence of <i>k</i>₁ on the homeostatic behavior of the m7 ping-pong controller when <i>E</i>₁ binds first to free enzyme <i>Ez</i>. by Qaiser Waheed (5095328)

“…(c) A decrease of <i>k</i>₆ from 5.0 to 1.0 while <i>k</i>₁ is kept at 100.0 gives a general improvement of the homeostatic performance of the ping-pong controller, except for the higher end <i>k</i>₅ range between 900–1000, where <i>A</i>_<i>ss</i> becomes constant (indicated by the red circle). …”

Psychophysical performance of Exposed (square data points) and Unexposed (round data points) groups. by Thomas J. Brozoski (421479)

“…After 72 hrs of D-AP5 infusion the treated Exposed group significantly diverged from the untreated Exposed group (statistics summarized in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0077674#pone-0077674-t001" target="_blank">Table 1</a>, section 2), indicating decreased tinnitus. …”

Effects of the <i>rabx-5</i> mutation are specific to early endosomal and synaptic compartments. by Sharon B. Sann (320476)

Oxidative stress in INS1E and alphaTC1 cells in 3D aggregates. by Mireille M. J. P. E. Sthijns (12245491)

“…N = 3, n≥2 and data are presented as mean ± SEM; * <i>p</i>≤0.05, all p-values are shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0257578#pone.0257578.s008" target="_blank">S8</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0257578#pone.0257578.s009" target="_blank">S9</a> Tables.…”

Effect of testosterone treatment on ligand-dependent activation of the EGFR and downstream signaling pathways in smooth muscle vascular cells. by Marta del Campo (596854)

“…<p>Serum starved SMVC were incubated with 10% (w/v) trichloroacetic acid. The samples were processed by Western blots using the indicated antibodies to determine the phosphorylation levels of the EGFR, p115, Akt, and ERK1/2, and the total levels of EGFR Akt, ERK1/2 and GAPDH as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0102523#s2" target="_blank">Materials and Methods</a>. …”

Up-regulation of pro-survival proteins and heat shock proteins in the hearts of ErbB2 transgenic mice. by Polina Sysa-Shah (144392)

“…<p>(A) Bcl-2 and Bcl-xL levels are increased, Bcl-xS levels are decreased and bcl-xS/XL ratio is reduced in left ventricles of ErbB2 transgenic mice. …”

Tanshinone IIA arrested PASMCs in G1/G0-phase under hypoxic condition. by Ying Luo (381053)

“…Hypoxia for 24 h decreased PASMCs in G0/G1-phase and increased PASMCs in G2/S-phase. …”

Effects of tiger17 on the MAPKs signal pathway. by Jing Tang (33607)

“…<p>(A) Raw 264.7 cells were treated with the indicated concentrations of tiger17 (2.5, 5, 10, 20 μg/ml) or vehicle; Western blotted for total or phospho-JNK, Erk or P38 was performed. β-Actin was used as the internal control. …”

Skeletal and dental effects on rats following <i>in utero</i>/lactational exposure to the non-dioxin-like polychlorinated biphenyl PCB 180 by Ashly N. Romero (3393503)

“…In a sample of 35- and 84-day-old male and female offspring from pregnant rats exposed to different doses of PCB 180 (0, 10, 30, 100, 300, and 1000 mg/kg bw), we measured the three-dimensional (3D) coordinates of 27 landmarks on the craniofacial skeleton with a Microscribe G2X system, the buccolingual width of all molars with digital sliding calipers, and a variety of tibial parameters with peripheral quantitative computed tomography (pQCT) and a biomechanical testing apparatus. …”

Baseline Omega-3 Index Correlates with Aggressive and Attention Deficit Disorder Behaviours in Adult Prisoners by Barbara J. Meyer (707249)

“…<div><p>Background</p><p>There is emerging evidence that the supplementation of omega-3 contributes to a decrease in aggressive behaviour in prison populations. …”

Key pathways with metabolic alterations in <i>pex</i> mutant flies. by Michael F. Wangler (544124)

“…Four analytes representing fatty dicarboxylates are shown with significant increases in the pex mutants over the corresponding rescue line for each mutation (see also <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006825#pgen.1006825.s014" target="_blank">S1 Table</a>). …”

Summary of alterations in fundamental parameters of the mitochondrial respiratory chain in nematodes deficient in mitochondrial dynamics and homeostasis processes. by Anthony L. Luz (759927)

“…</p><p>**<i>isp-1</i> mitochondria could not be quantified, likely due to poor MitoTracker Red CMXROS uptake due to decreased mitochondrial membrane potential [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0130940#pone.0130940.ref059" target="_blank">59</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0130940#pone.0130940.ref060" target="_blank">60</a>].…”