ROC plots for comparison of 3D classifiers to sequence-based prediction shows significant decrease of false-positive rates. by Jasmin F. Sydow (588118)

Reproductive Toxicity and Teratogenicity of Fluorene-9-bisphenol on Chinese Medaka (Oryzias sinensis): A Study from Laboratory to Field by Xiaolin Fan (1605136)

“…Toxico-transcriptome analyses showed that estrogen-responsive genes were significantly suppressed by BHPF, indicating that antagonist properties of BHPF on estrogen receptors might be causes for the decreased fecundity. Field investigations (Beijing) demonstrated that BHPF was detectable in 60% surface waters, with a mean concentration of 10.49 ± 6.33 ng/L, by gas chromatography–mass spectrometry, and similar effects in wild Chinese medaka were also observed, some of which the parameters were found to be obviously correlated with the BHPF levels in corresponding waters.…”

Reproductive Toxicity and Teratogenicity of Fluorene-9-bisphenol on Chinese Medaka (Oryzias sinensis): A Study from Laboratory to Field by Xiaolin Fan (1605136)

“…Toxico-transcriptome analyses showed that estrogen-responsive genes were significantly suppressed by BHPF, indicating that antagonist properties of BHPF on estrogen receptors might be causes for the decreased fecundity. Field investigations (Beijing) demonstrated that BHPF was detectable in 60% surface waters, with a mean concentration of 10.49 ± 6.33 ng/L, by gas chromatography–mass spectrometry, and similar effects in wild Chinese medaka were also observed, some of which the parameters were found to be obviously correlated with the BHPF levels in corresponding waters.…”

Reproductive Toxicity and Teratogenicity of Fluorene-9-bisphenol on Chinese Medaka (Oryzias sinensis): A Study from Laboratory to Field by Xiaolin Fan (1605136)

“…Toxico-transcriptome analyses showed that estrogen-responsive genes were significantly suppressed by BHPF, indicating that antagonist properties of BHPF on estrogen receptors might be causes for the decreased fecundity. Field investigations (Beijing) demonstrated that BHPF was detectable in 60% surface waters, with a mean concentration of 10.49 ± 6.33 ng/L, by gas chromatography–mass spectrometry, and similar effects in wild Chinese medaka were also observed, some of which the parameters were found to be obviously correlated with the BHPF levels in corresponding waters.…”

NBCe1 protein expression regulation by D₁-like (D₁R and D₅R) dopamine receptor agonist in hRPTCs carrying wild-type (WT) <i>SLC4A5</i>. by John J. Gildea (845025)

“…<p>NBCe1 protein expression is decreased following an increase in intracellular sodium (↑Na⁺) (10 μmol monensin/L, 24 h) (N = 4, *P<0.001 vs VEH, one-way ANOVA, Tukey’s test) in WT <i>SLC4A5</i> hRPTC. …”

Chronic administration of SAHA decreases HDAC4 levels and reduces aggregate load – 1^st trial. by Michal Mielcarek (195209)

Truncation or mutation of MinE’s membrane targeting sequence decreases the lower limit of the length scale of Min protein patterns. by Simon Kretschmer (1871506)

DataSheet_1_Hepatic-Specific Decrease in the Expression of Selenoenzymes and Factors Essential for Selenium Processing After Endotoxemia.docx by Laura G. Sherlock (9602411)

“…</p>Methods<p>Wild type (WT) adult male C57/B6 mice were exposed to LPS (5 mg/kg, intraperitoneal). …”

Dorsal dermis is decreased in dermis thickness and number of hair follicles in the <i>Wnt11</i> knock-out mice. by Gabriela Morosan-Puopolo (211008)

“…The white square shows a decrease number of hair placodes in comparison to the WT embryo of similar developmental stage (B). …”

<i>Ngl3</i> deletion in mice decreases birth rate and suppresses postnatal growth, survival, and brain development. by Hyejin Lee (636530)

“…<i>n</i> = 61 mice for WT, 118 for HT, and 30 for KO. (C) Altered gross morphology of the <i>Ngl3</i>^{<i>−/−</i>(B6)} brain (10 weeks), revealed by HE staining. …”

CX3CR1-/- primary microglia show decreased internalization of α-syn and phagocytosis <i>in vitro</i>. by Aaron D. Thome (813759)

iNOS deficiency ameliorated increased expression of atrogenes and decreased cross-sectional area in skeletal muscle of burned mice. by Harumasa Nakazawa (684211)

“…<p>A, B, At 3 days after burn or sham-burn, mRNA levels of atrogenes, Murf1 and atrogin-1, were significantly increased by burn injury in wild-type (WT) mice. Burn-induced increase in mRNA levels of these genes was attenuated in iNOS knockout (iNOS KO) mice. n = 3 mice per group for Sham; n = 5 mice per group for Burn. …”

Decreased erythropoiesis related gene expression in the bone marrow of <i>Thra1</i>^PV/+ mice. by Sunmi Park (2051092)

Absence of RstA leads to a decrease in the number of origins per cell. by Yuan Yao (31223)

Decreasing the number of miR-142-3p binding sites leads to increased virus replication in myeloid cells. by Derek W. Trobaugh (6321476)

Inhibition of HDAC6 activity decreased the phosphorylation of ERK1/2 and normalized the localization of EGFR from apical to basolateral. by Wei Liu (20030)

“…<p>(A) Knockdown HDAC6 with shRNA increases the degradation of EGFR and decreases the phosphorylation of ERK1/2. …”

NO donor dose dependently decreases cell number induced by PDGF-BB and blocks survivin expression and <i>in vitro</i>. by Jun Yu (5904)

“…<p>(A), Rat SMC were treated or not with PDGF (10 ng/ml), in the absence or presence of the NO donor, DETA/NO (10, 30, and 100 µM) and cell number quantified after 48 h. …”

Expression of p120-catenin phosphorylation dead mutant leads to decreased tumor cell metastasis <i>in-vivo</i>. by Alisha M. Mendonsa (9033917)

“…(C) Weight in grams of primary tumor at 4 weeks post injection showed no significant difference between WT and S/T6A p120-catenin expressing tumors. Number of (D) surface lung metastases or (E) total number of tumors determined through H&E staining showing a decrease in metastatic ability of 4T1 cells expressing the S/T6A versus WT p120-catenin. …”

nsP4-C483Y or Q192L mutations decrease sensitivity to 4′-FlU. by Peiqi Yin (6533747)

Inhibition of Wnt signaling pathway or absence of TSP1 decreases cellular <i>T</i>. <i>cruzi</i> infection. by Ashutosh Arun (2574559)