Under microaerobic (1% O₂) conditions in free living cells, the hFixL-FxkR-FixK pathway and not FnrN is a key activator of anaerobox controlled genes. by Paul J. Rutten (10099255)

“…The <i>hfixL</i>₉ homolog had a far more pronounced effect on expression of all three genes than did the <i>hfixL</i>_c homolog. …”

The effects of human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) transplantation on renal function (A and B) and renal histology (C to G) of NOD-SCID mice treated with... by Te-Chao Fang (305300)

“…Three days after folic acid, renal tubular cell damage was severe in folic acid-injured NOD-SCID mice (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046504#pone-0046504-g002" target="_blank">Figure 2E</a>) and administration of hUC-MSCs to folic acid-injured NOD-SCID mice could decrease renal tubular cell damage (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046504#pone-0046504-g002" target="_blank">Figure 2F</a>). …”

Inhibition of cilia disassembly protects RGCs and suppresses cell cycling after ONT. by Brian K. A. Choi (7114916)

“…Scale bar = 100 μm. (B) Quantification of RGCs after intravitreal injection of the TBA (n = 4 retinas) or AurA inhibitor I (n = 5 retinas), demonstrating significantly increased RGC survival at 14 days post-ONT compared to DMSO control treatment (**p<0.01). …”

Image_4_Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR.png by Yamina El Hamdaoui (6759080)

“…Two-electrode voltage clamp analysis on oocyte-expressed nAChR subtypes demonstrated the functionality of these peptides but also revealed a 30 to 100-fold potency decrease of expressed TxIA compared to chemically synthesized TxIA. …”

Image_2_Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR.JPEG by Yamina El Hamdaoui (6759080)

“…Two-electrode voltage clamp analysis on oocyte-expressed nAChR subtypes demonstrated the functionality of these peptides but also revealed a 30 to 100-fold potency decrease of expressed TxIA compared to chemically synthesized TxIA. …”

Image_1_Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR.JPEG by Yamina El Hamdaoui (6759080)

“…Two-electrode voltage clamp analysis on oocyte-expressed nAChR subtypes demonstrated the functionality of these peptides but also revealed a 30 to 100-fold potency decrease of expressed TxIA compared to chemically synthesized TxIA. …”

Image_3_Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR.JPEG by Yamina El Hamdaoui (6759080)

“…Two-electrode voltage clamp analysis on oocyte-expressed nAChR subtypes demonstrated the functionality of these peptides but also revealed a 30 to 100-fold potency decrease of expressed TxIA compared to chemically synthesized TxIA. …”

Table_1_Association between serum iron levels and atherosclerotic cardiovascular diseases among American older adults: a cross-sectional study based on the National Health and Nutr... by Xiaochen Yu (3796927)

“…For serum iron levels below 131 μg/dL, each 10 μg/dL increase was associated with a 4% decrease in the odds of ASCVD (OR = 0.96; 95% CI, 0.93–0.98, p < 0.001). …”

Manipulation of AMPK pathway affects performance in the LGMD/DCMD circuit. by Tomas G. A. Money (522109)

“…<p>(<b>A</b>). Metformin application (arrow) results in a decreased responsiveness to repeated looming stimuli. …”

Export flux succession of dinoflagellate cysts and planktonic foraminifera in an active upwelling cell off Cape Blanc (NW Africa) by Karin A.F. Zonneveld (10777280)

“…<p>To better understand production, succession, excystment and transport of dinoflagellate cysts (dinocysts) and planktonic foraminifera in the upper water column, we investigated their fluxes during a 7-day survey in the active upwelling off Cape Blanc (NW Africa) in November 2018 with drifting traps at 100 m, 200 m and 400 m water depth. …”

Morin, a Bioflavonoid Suppresses Monosodium Urate Crystal-Induced Inflammatory Immune Response in RAW 264.7 Macrophages through the Inhibition of Inflammatory Mediators, Intracellu... by Chitra Dhanasekar (841574)

“…For comparison purpose, colchicine was used as a reference drug. We have observed that morin (100–300 μM) treatment significantly suppressed the levels of inflammatory cytokines (TNF-α, IL-1β, IL-6, MCP-1 and VEGF), inflammatory mediators (NO and PEG₂), and lysosomal enzymes (acid phosphatase, β-galactosidase, N-acetyl glucosamindase and cathepsin D) in MSU-crystals stimulated macrophage cells. …”

Data Sheet 1_Excess mortality in young cancer survivors compared with the general population in Italy: a retrospective study from the Italian population-based cohort of adolescents... by Paolo Giorgi Rossi (9311547)

“…Young adult cancer survivors face a sevenfold increase in all-cause mortality compared to the general population, with a notable rise in both cancer-related and non-cancer deaths. …”

C2GnT1 mediates invasion. by Catherine A. St. Hill (357388)

“…(B) Similarly, decreased invasion was observed for HepG2 cells that were transfected with C2GnT1 shRNA compared to transfection with a control vector, *p = 0.0005. …”

A Synthetic, Structural, Magnetic, and Spectral Study of Several {Fe[tris(pyrazolyl)methane]₂}(BF₄)₂ Complexes:  Observation of an Unusual Spin-Sta... by Daniel L. Reger (1444537)

“…In the solid phase, it undergoes a decrease in magnetic moment at lower temperatures, changing at ca. 206 K to a mixture of high-spin and low-spin forms, a spin-state mixture that does not change upon subsequent cooling to 5 K. …”

Data_Sheet_1_Direct Oral Anticoagulants vs. Vitamin-K Antagonists in the Elderly With Atrial Fibrillation: A Systematic Review Comparing Benefits and Harms Between Observational St... by Nan-Nan Shen (1536292)

“…Compared with VKAs, DOACs significantly reduced risk for stroke/SE (OSs, HR: 0.87, 95% CI: 0.81–0.94; RCT, RR: 0.82, 95% CI: 0.67–0.96), and ICH (OSs: 0.47 [0.37–0.57]; RCTs: 0.47 [0.31–0.63]), without increasing risk for GIB (OSs: 1.21 [0.98–1.43]; RCTs: 1.34 [0.91–1.77]), and all-cause mortality (OSs: 1.01 [0.92–1.11]; RCTs: 0.94 [0.87–1.00]). Among OSs, DOACs significantly decreased risk for major bleeding (0.87 [0.77–0.98]) and MI (0.89 [0.79–0.99]). …”

Biomass and water use efficiency of chrysanthemum under organic, mineral, and organomineral fertilization by Luana A. M. Meneghetti (14820688)

“…The greenhouse experiment was conducted in a 5 × 2 factorial randomized block design with five fertilization managements (incubated wood ash, non-incubated wood ash, organomineral, mineral fertilization, and control) and two liming values (0 and 100% of the recommendation), with five replicates. …”

Use of sugar cane to feed lactating dairy goats by A.M.D. Cabral (10387782)

“…The experimental diets were composed of increasing levels (0, 33, 66 and 100%) of substitution in dry matter (DM). Twelve multiparous Saanen goats, with an average body weight of 45.2kg, average milk yield of 3.0kg day-1, distributed in a triple latin square experimental design (4 × 4) were used. …”

Data Sheet 7_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

“…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”

Data Sheet 3_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

“…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”

Data Sheet 4_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

“…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”